Major Facilitator Superfamily Domain Containing 2A (MFSD2A) ELISA试剂盒

Plays a role in thermogenesis via beta-adrenergic signaling pathway. 再加上,我们可以发MFSD2A 抗体 (32)MFSD2A 蛋白 (3)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
MFSD2A 84879 Q8NA29
MFSD2A 76574 Q9DA75
大鼠 MFSD2A MFSD2A 298504  

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0.23 ng/mL 0.312-20 ng/mL   96 Tests Log in to see 24至29个工作日
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0.237 ng/mL 0.62-40 ng/mL 96 Tests Log in to see 7至10个工作日
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Human Major Facilitator Superfamily Domain Containing 2A (MFSD2A) interaction partners

  1. The regulatory role of Mfsd2a deepens our knowledge of the function of the BBB (显示 ALMS1 ELISA试剂盒), potentially contributing to the effective drug delivery in the treatments for neurodegenerative diseases, brain tumors, and life-threatening infections in the CNS

  2. MFSD2A transported structurally related acylcarnitines but not a lysolipid without a negative charge, demonstrating the necessity of a negatively charged headgroup interaction with Lys (显示 LYZ ELISA试剂盒)-436 for transport.

  3. A homozygous mutation affecting a highly conserved MFSD2A residue (p.Ser339Leu) is associated with a progressive microcephaly syndrome characterized by intellectual disability, spasticity and absent speech.

  4. MFSD2A mutations impair brain lipid transport activity.

  5. Several tagging SNPs and haplotypes in TRIT1, MYCL1 and MFSD2A region are significantly associated with risk and clinicopathological features of gastric cancer in a Chinese population.

  6. Importance of MFSD2a in trophoblast fusion and placenta development.

  7. SNP rs12072037 modulates MFSD2A promoter activity and thus might affect MFSD2A levels in normal lung and in lung tumors.

  8. MFSD2A is a putative Tunicamycin transporter at the plasma membrane.

  9. MFSD2A is a novel lung cancer tumor suppressor gene that regulates cell cycle progression and matrix attachment.

  10. three additional SNPs in the MFSD2 genes showed ethnic differences in allelic frequencies

Mouse (Murine) Major Facilitator Superfamily Domain Containing 2A (MFSD2A) interaction partners

  1. Maternal DHA supplementation had a strong impact on offspring hepatic gene expression, especially of the fatty acid transporter, Mfsd2a, suggesting a dynamic interplay between DHA synthesis and DHA uptake in the control of systemic levels in the offspring

  2. Mfsd2a lipid transport function is required for suppression of transcytosis and blood brain barrier integrity.

  3. These findings identify LPC (显示 PCSK7 ELISA试剂盒) transport via Mfsd2a as an important pathway for DHA uptake in eye and for development of photoreceptor membrane discs.

  4. findings identify Mfsd2a as a key regulator of blood brain barrier function that may act by suppressing transcytosis in CNS endothelial cells.

  5. identification of a member of the major facilitator superfamily--Mfsd2a (previously an orphan transporter)--as the major transporter for docosahexaenoic acid uptake into brain

  6. Data suggest that the ligand(s) that are transported by MFSD2A play important roles in these physiological processes and await future identification.

  7. Results identify Mfsd2a (major facilitator superfamily domain-containing protein 2a) and an additional closely related protein Mfsd2b, and suggest that Mfsd2a plays a role in adaptive thermogenesis.

MFSD2A 抗原简介

Antigen Summary

Plays a role in thermogenesis via beta-adrenergic signaling pathway. May be the main plasma membrane tunicamycin transporter.

Gene names and symbols associated with MFSD2A

  • major facilitator superfamily domain containing 2A (MFSD2A) 抗体
  • major facilitator superfamily domain containing 2A (mfsd2a) 抗体
  • major facilitator superfamily domain containing 2A (Mfsd2a) 抗体
  • 1700018O18Rik 抗体
  • Mfsd2 抗体
  • RGD1310174 抗体

Protein level used designations for MFSD2A

major facilitator superfamily domain containing 2 , major facilitator superfamily domain containing 2A , major facilitator superfamily domain-containing protein 2A

GENE ID SPECIES
100068365 Equus caballus
718876 Macaca mulatta
100025155 Monodelphis domestica
100441975 Pongo abelii
100476592 Ailuropoda melanoleuca
100565013 Anolis carolinensis
419679 Gallus gallus
84879 Homo sapiens
475318 Canis lupus familiaris
100518612 Sus scrofa
512633 Bos taurus
76574 Mus musculus
298504 Rattus norvegicus
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