Maelstrom Spermatogenic Transposon Silencer (MAEL) ELISA试剂盒

Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. 再加上,我们可以发MAEL 蛋白 (6)MAEL 抗体 (5)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
MAEL 98558 Q8BVN9
MAEL 84944 Q96JY0
大鼠 MAEL MAEL 364039  

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适于 MAEL 相互作用对的更多 ELISA 试剂盒

Mouse (Murine) Maelstrom Spermatogenic Transposon Silencer (MAEL) interaction partners

  1. MAEL HMG (显示 SSRP1 ELISA试剂盒)-box domain may contribute to MAEL function in selective processing of retrotransposon RNA into piRNAs.

  2. an important role for Mael in early oogenesis and during germ-cell differentiation from embryonic stem cells

  3. This study demonstrates that MAEL, a nuage component, is indispensable for the silencing of transposable elements (TEs (显示 TES ELISA试剂盒)) and identifies the initiation of meiosis as an important step in (TE) control in the male germline.

Human Maelstrom Spermatogenic Transposon Silencer (MAEL) interaction partners

  1. Data suggest that overexpression of MAEL, caused by gene amplification and/or decreased miR-186, has a critical oncogenic role in UCB pathogenesis by downregulation of MTSS1.

  2. Study demonstrated that MAEL interacts with Snail (显示 SNAI1 ELISA试剂盒) and inhibit E-cadherin (显示 CDH1 ELISA试剂盒) promoter activity. MAEL is an oncogene (显示 RAB1A ELISA试剂盒) that plays an important role in the development and progression of colon cancer.

  3. Immunofluorescence analysis showed that MAEL co-localizes with the stress granule marker PABPC1 (显示 PABPC1 ELISA试剂盒) in stress granules during oxidative stress. MAEL may be involved in miRNA-mediated gene silencing in SGs (显示 FBN1 ELISA试剂盒).

  4. Maelstrom promotes hepatocellular carcinoma metastasis by inducing epithelial-mesenchymal transition by way of Akt (显示 AKT1 ELISA试剂盒)/GSK-3beta (显示 GSK3b ELISA试剂盒)/Snail (显示 SNAI1 ELISA试剂盒) signaling.

  5. These results suggest that MAEL is a novel cancer/testis-associated gene and is regulated by DNA methylation (显示 HELLS ELISA试剂盒).

MAEL 抗原简介

Antigen Summary

Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for localization of germ-cell factors to the meiotic nuage (By similarity).

Gene names and symbols associated with MAEL

  • maelstrom homolog (Drosophila) (Mael) 抗体
  • maelstrom homolog (Drosophila) (MAEL) 抗体
  • maelstrom spermatogenic transposon silencer (MAEL) 抗体
  • maelstrom spermatogenic transposon silencer (Mael) 抗体
  • protein maelstrom homolog (LOC100737640) 抗体
  • 4933405K18Rik 抗体
  • AU019877 抗体
  • CT128 抗体
  • RGD1309333 抗体
  • RP11-102C16.1 抗体
  • SPATA35 抗体

Protein level used designations for MAEL

protein maelstrom homolog , cancer/testis antigen 128 , maelstrom homolog , spermatogenesis associated 35

GENE ID SPECIES
98558 Mus musculus
541073 Bos taurus
100048945 Sus scrofa
84944 Homo sapiens
364039 Rattus norvegicus
100737640 Sus scrofa
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