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MSR1 encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of MSR1. 再加上，我们可以发Macrophage Scavenger Receptor 1 抗体 (254) 和 Macrophage Scavenger Receptor 1 蛋白 (16)和数多这个蛋白质的别的产品。
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Human Macrophage Scavenger Receptor 1 ELISA Kit for Sandwich ELISA - ABIN417678
Zuo, Yu, Guo, Wang, Qian, Yi, Lu, Lv, Subjeck, Zhou, Sanyal, Chen, Wang: Scavenger receptor A restrains T-cell activation and protects against concanavalin A-induced hepatic injury. in Hepatology (Baltimore, Md.) 2013
SR-A1 suppresses lung cancer metastasis by downregulating SAA1 (显示 SAA1 ELISA试剂盒) production in tumor-associated macrophages (TAM (显示 CCNA1 ELISA试剂盒)).
PTX2 (显示 APCS ELISA试剂盒) was identified PTX2 (显示 APCS ELISA试剂盒) as a novel partner for FX, and both proteins cooperated to prevent their SR-AI-mediated uptake by macrophages.
we found that higher percentages of circulating CD14 (显示 NDUFA2 ELISA试剂盒)+CD204+, CD14 (显示 NDUFA2 ELISA试剂盒)+CD163 (显示 CD163 ELISA试剂盒)+CD204+ M2-like monocytes were significantly associated with TNM (显示 ODZ1 ELISA试剂盒) stage, lymph node metastasis, and histological differentiation.
Identifying N-linked glycan moiety and motifs in the cysteine-rich domain critical for N-glycosylation and intracellular trafficking of SR-AI and MARCO (显示 MARCO ELISA试剂盒).
The P275A Polymorphism in the Macrophage Scavenger Receptor 1 Gene is not associated with Prostate Cancer Risk.
Cyr61 (显示 CYR61 ELISA试剂盒) promotes CD204 expression and the migration of macrophages via MEK (显示 MAP2K1 ELISA试剂盒)/ERK (显示 EPHB2 ELISA试剂盒) pathway in esophageal squamous cell carcinoma
miR (显示 MLXIP ELISA试剂盒)-29a promotes scavenger receptor A expression by targeting QKI (显示 QKI ELISA试剂盒) during monocyte-macrophage differentiation.
Heptapeptide XD4 activates the class A scavenger receptor (SR-A) on the glia by increasing the binding of Abeta (显示 APP ELISA试剂盒) to SR-A, thereby promoting glial phagocytosis of Abeta (显示 APP ELISA试剂盒) oligomer in microglia.
The truncating variant Arg293X in the gene encoding SRA (显示 SRA1 ELISA试剂盒)-I/II was associated with reduced lung function and with increased risk of COPD (显示 ARCN1 ELISA试剂盒) among men, as well as among alpha1-antitrypsin MZ and superoxide dismutase (显示 SOD1 ELISA试剂盒)-3 E1I1 heterozygotes.
monomeric collagen type I via CD204 induces phospho-Akt (显示 AKT1 ELISA试剂盒) expression shifting alveolar macrophages to the profibrotic M2 type. Innate immune responses induced by collagen monomers might perpetuate pulmonary fibrosis.
Data (including data from studies conducted in cells from knockout mice) suggest that signaling via Lpar1 (显示 LPAR1 ELISA试剂盒), Cd14 (显示 CD14 ELISA试剂盒), and Scara1 mediates uptake of oxidized LDL by macrophages leading to foam cell formation; lysophosphatidic acid (LPA) induces expression of Cd14 (显示 CD14 ELISA试剂盒) and Scara1 in macrophages. (Lpar1 (显示 LPAR1 ELISA试剂盒) = LPA receptor 1 (显示 LPAR1 ELISA试剂盒); Cd14 (显示 CD14 ELISA试剂盒) = monocyte differentiation antigen CD14 (显示 CD14 ELISA试剂盒); Scara1 = scavenger receptor class A type I)
Common damage-associated molecular patterns (DAMPs) were internalized through the class A scavenger receptors MSR1 and MARCO (显示 MARCO ELISA试剂盒) in vitro. In ischemic murine brain, DAMP (显示 AMPH ELISA试剂盒) internalization was largely mediated by MSR1. Combined deficiency for Msr1 and Marco (显示 MARCO ELISA试剂盒) in infiltrating myeloid cells caused impaired clearance of DAMPs, more severe inflammation, and exacerbated neuronal injury in a murine model of ischemic stroke.
PTX2 (显示 PITX2 ELISA试剂盒) was identified PTX2 (显示 PITX2 ELISA试剂盒) as a novel partner for FX, and both proteins cooperated to prevent their SR-AI-mediated uptake by macrophages.
this study shows that Msr1 functions as co-receptor along with TLRs for HMGB1 (显示 HMGB1 ELISA试剂盒) in M1-type inflammatory macrophages
Our findings demonstrated that ClC-3 (显示 CLCN3 ELISA试剂盒) deficiency inhibits atherosclerotic lesion development, possibly via suppression of JNK (显示 MAPK8 ELISA试剂盒)/p38 MAPK (显示 MAPK14 ELISA试剂盒) dependent SR-A expression and foam cell formation
FAP (显示 FAP ELISA试剂盒)-cleaved collagen is a substrate for SR-A-dependent macrophage adhesion.
Macrophages regulate FX plasma levels in an SR-AI-dependent manner.
The results of this results reveal that SRA has important clinical implications for TLR-targeted immunotherapeutical strategy in intracerebral hemorrhage.
these findings suggest that SR-A-mediated dsRNA internalization is independent of innate antiviral signaling.
Our findings imply that SR-A may be an important target for improving therapeutic strategies for type 1 diabetes.
This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages.
macrophage acetylated LDL receptor I and II
, macrophage scavenger receptor type III
, macrophage scavenger receptor types I and II
, scavenger receptor class A member 1
, scavenger receptor class A, member 1
, scavenger receptor type A
, macrophage scavenger receptor 1
, macrophage scavenger receptor type I
, macrophage scavenger receptor types I and II-like