anti-M-Phase phosphoprotein 8 (MPHOSPH8) 抗体

Involved in transcriptional regulation. 再加上,我们可以发M-Phase phosphoprotein 8 蛋白 (4)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
MPHOSPH8 54737 Q99549
MPHOSPH8 75339 Q3TYA6
MPHOSPH8 290270 G3V8T1

antibodies-online.cn销售最多的anti-M-Phase phosphoprotein 8 抗体

Showing 10 out of 18 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
小鼠 非结合性 WB MPP8 antibody (mAb) tested by Western blot. Nuclear extract of HEK293 cells (20 µg per lane) probed with MPP8 antibody (mAb) (2 µg/ml dilution). 100 μg Log in to see 23至29个工作日
¥4,264.21
详细
非结合性 IP, WB Western Blot: mpp8 Antibody [NBP1-71808] - Whole cell lysate (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-MPP8 antibody used for WB at 0.1 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 6 mcg/mg lysate. MPP8 was also immunoprecipitated by rabbit anti-MPP8 antibody NBP1-71807, which recognizes a downstream epitope. 100 μL Log in to see 25至31个工作日
¥3,977.17
详细
非结合性 IP, WB Western Blot: mpp8 Antibody [NBP1-71809] - Whole cell lysate (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) from HeLa cells. Affinity purified rabbit anti-MPP8 antibody used for WB at 0.1 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 6 mcg/mg lysate. MPP8 was also immunoprecipitated by rabbit anti-MPP8 antibody NBP1-71808, which recognizes an upstream epitope. 100 μL Log in to see 25至31个工作日
¥3,977.17
详细
非结合性 ICC, IF, IHC, IHC (p), WB Western Blot: mpp8 Antibody [NBP1-92136] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp Immunocytochemistry/Immunofluorescence: mpp8 Antibody [NBP1-92136] - Staining of human cell line U-251 MG shows positivity in nucleus but not nucleoli & cytoplasm. 0.1 mL Log in to see 28至35个工作日
¥3,591.24
详细
小鼠 非结合性 IF, WB Western Blot analysis of MPHOSPH8 expression in transfected 293T cell line by MPHOSPH8 MaxPab polyclonal antibody.Lane 1: MPHOSPH8 transfected lysate(28.40 KDa).Lane 2: Non-transfected lysate. Immunofluorescence of purified MaxPab antibody to MPHOSPH8 on HeLa cell. [antibody concentration 10 ug/ml] 50 μL Log in to see 29至34个工作日
¥3,169.73
详细
非结合性 ELISA, WB   50 μL Log in to see 7至10个工作日
¥2,864.83
详细
非结合性 WB   100 μL Log in to see 33至42个工作日
¥6,877.38
详细
小鼠 非结合性 WB   10 μg Log in to see 23至29个工作日
¥1,167.30
详细
非结合性 WB   200 μL Log in to see 29至38个工作日
¥5,224.89
详细
非结合性 ELISA, WB   50 μL Log in to see 24至29个工作日
¥12,826.01
详细

通过反应活性、应用领域、克隆类型和共轭标记 MPHOSPH8 抗体

特性 应用范围 宿主 克隆类型
Human
,
,
Mouse (Murine)


Rat (Rattus)


更多抗M-Phase phosphoprotein 8的相互作用对抗体

Human M-Phase phosphoprotein 8 (MPHOSPH8) interaction partners

  1. The haploid screen identified HUSH, an epigenetic heterochromatin repressor complex composed of three subunits, TASOR, MPP8 and Periphilin (显示 PPHLN1 抗体). (Review)

  2. findings demonstrate MPP8 and SIRT1 (显示 SIRT1 抗体) reciprocally regulate each other's function at multiple molecular layers through physical interaction; disruption of MPP8-SIRT1 (显示 SIRT1 抗体) interaction de-represses E cadherin (显示 CDH1 抗体) expression and reduces cell motility and invasiveness suggesting this interplay plays critical role in MPP8- and SIRT1 (显示 SIRT1 抗体)-mediated epithelial-mesenchymal transition

  3. this study identified the HUSH (human silencing hub) complex, comprising three poorly characterized proteins, TASOR, MPP8, and periphilin (显示 PPHLN1 抗体); this complex is absent from Drosophila but is conserved from fish to humans.

  4. Knockdown analysis of MPP8 in HeLa cells resulted in derepression of a set of genes that are normally expressed in spermatogonia, spermatids and mature sperm, thereby indicating a role for this molecule in silencing testis-related genes in somatic cells.

  5. interaction of HN with MPP8 may play a role in oncogenesis because MPP8 increases tumor cell motility and invasion

  6. these results indicate that the chromatin association of MPP8 is regulated by Cdk (显示 CDK4 抗体)-dependent phosphorylation.

  7. These findings reveal the molecular mechanism of selective binding of human MPP8 chromodomain to methylated histone H3K9.

  8. We determined the crystal structure of MPP8 chromodomain in complex with H3K9me3 peptide. MPP8 interacts with at least six histone H3 (显示 HIST3H3 抗体) residues from glutamine (显示 GFPT1 抗体) 5 to serine 10.

  9. MPP8 mediates E-cadherin (显示 CDH1 抗体) gene silencing and promotes breast tumour cell motility and invasion.

M-Phase phosphoprotein 8 (MPHOSPH8) 抗原简介

蛋白简介

Involved in transcriptional regulation. Specifically recognizes and binds methylated 'Lys-9' of histone H3 (H3K9me) and promotes DNA methylation by recruiting DNMT3A to target CpG sites\; these can be situated within the coding region of the gene. Mediates down-regulation of CDH1 expression (By similarity).

Gene names and symbols associated with MPHOSPH8

  • M-phase phosphoprotein 8 (MPHOSPH8) 抗体
  • M-phase phosphoprotein 8 (Mphosph8) 抗体
  • 1500035L22Rik 抗体
  • 4930548G07Rik 抗体
  • Ab2-008 抗体
  • AU040635 抗体
  • HSMPP8 抗体
  • mpp8 抗体
  • RGD1305133 抗体
  • TWA3 抗体

Protein level used designations for MPHOSPH8

M-phase phosphoprotein, mpp , M-phase phosphoprotein, mpp8 , two hybrid-associated protein 3 with RanBPM

GENE ID SPECIES
54737 Homo sapiens
75339 Mus musculus
290270 Rattus norvegicus
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