anti-MCF.2 Cell Line Derived Transforming Sequence (MCF2) 抗体

The oncogenic protein encoded by MCF2 is a guanine nucleotide exchange factor (GEF) that exerts control over some members of the Rho family of small GTPases. 再加上,我们可以发MCF2 蛋白 (3)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
MCF2 4168 P10911
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产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 EIA, FACS, IHC (p), WB Flow cytometric analysis of K562 cells using MCF2 Antibody (C-term) Cat.-No AP52634PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis. Immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue reacted with MCF2 Antibody (C-term) followed which was peroxidase conjugated to the secondary antibody and followed by DAB staining. 0.4 mL Log in to see 6至8个工作日
$390.50
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非结合性 FACS, IHC (p), WB MCF2 Antibody (C-term) (ABIN656494) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10至11个工作日
$324.50
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非结合性 ELISA, FACS, IHC, WB   200 μL Log in to see 7至9个工作日
$793.83
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APC FACS, IHC, ELISA, WB   200 μL Log in to see 7至9个工作日
$1,013.83
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Biotin FACS, IHC, ELISA, WB   200 μL Log in to see 7至9个工作日
$1,013.83
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FITC FACS, IHC, ELISA, WB   200 μL Log in to see 7至9个工作日
$1,013.83
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PE FACS, IHC, ELISA, WB   200 μL Log in to see 7至9个工作日
$1,013.83
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Alkaline Phosphatase (AP) FACS, IHC, ELISA, WB   200 μL Log in to see 7至9个工作日
$1,013.83
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HRP FACS, IHC, ELISA, WB   200 μL Log in to see 7至9个工作日
$1,013.83
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非结合性 FACS, IHC, ELISA, WB   200 μL Log in to see 11至16个工作日
$594.00
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通过反应活性、应用领域、克隆类型和共轭标记 MCF2 抗体

特性 应用范围 宿主 克隆类型 标记
Human
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更多抗MCF2的相互作用对抗体

Human MCF.2 Cell Line Derived Transforming Sequence (MCF2) interaction partners

  1. Results support a role for Dbl oncogene (显示 RAB1A 抗体) in mammary epithelial cell differentiation and transformation and suggest the relevance of GEF (显示 SLC2A4RG 抗体) deregulation in tumor onset and progression.

  2. Phosphoinositide 3-kinase C2beta regulates RhoA (显示 RHOA 抗体) and the actin cytoskeleton through an interaction with Dbl

  3. Dbl is regulated by hamartin (显示 TSC1 抗体) through association with ezrin (显示 EZR 抗体).

  4. proto-oncogene dbl is not a major target for sporadic testicular germ cell tumors

  5. data describe 4 splicing variants of the human DBL (MCF-2) proto-oncogene (显示 RAB1A 抗体) that show different tissue distributions and guanine nucleotide exchange factor (显示 RASGRF1 抗体) specificities

  6. provides fundamental data on the structure of Mcf-2, which regulates a variety of cellular signaling pathways

  7. These data suggest a mechanism whereby precise spatial guanine nucleotide exchange of Cdc42 (显示 CDC42 抗体) by Dbl is dependent on functional ERM (显示 ETV5 抗体) proteins and is important for directional cell migration.

  8. Galphaq (显示 GNAQ 抗体) directly activates p63RhoGEF and Trio (显示 TRIO 抗体) via a conserved extension of the Dbl homology-associated pleckstrin (显示 PLEK 抗体) homology domain

  9. Nm23-H1 (显示 NME1 抗体) can negatively regulate cell migration and tumor metastasis by modulating the activity of Cdc42 (显示 CDC42 抗体) and possibly other Rho family members through interaction with Dbl-1

MCF2 抗原简介

蛋白简介

The oncogenic protein encoded by this gene is a guanine nucleotide exchange factor (GEF) that exerts control over some members of the Rho family of small GTPases. Several transcript variants encoding different isoforms have been found for this gene. These isoforms exhibit different expression patterns and varying levels of GEF activity.

Gene names and symbols associated with MCF2

  • MCF.2 cell line derived transforming sequence (MCF2) 抗体
  • ARHGEF21 抗体
  • DBL 抗体

Protein level used designations for MCF2

Oncogene MCF2 (oncogene DBL) , proto-oncogene DBL , proto-oncogene MCF-2

GENE ID SPECIES
4168 Homo sapiens
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