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MXD3 encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. 再加上，我们可以发MAX Dimerization Protein 3 抗体 (50) 和 MAX Dimerization Protein 3 蛋白 (10)和数多这个蛋白质的别的产品。
The results suggest that MXD3 is important for survival of Reh (显示 CES1 ELISA试剂盒) preB (显示 PREB ELISA试剂盒) ALL cells, possibly as an anti-apoptotic factor.
Acute MXD3 activation results in a transient increase in DAOY cell proliferation while persistent activation of MXD3 results in an overall decrease in cell number, suggesting that the time course of MXD3 expression dictates the cellular outcome.
Increased level and/or duration of MXD3 expression ultimately reduces cell numbers via increased cell death and cell cycle arrest in medulloblastoma cells.
Mxd3 regulates preadipocyte proliferation and early adipocyte differentiation via Cebpd (显示 CEBPD ELISA试剂盒) downregulation in vitro and in vivo.
Results demonstrate that high expression levels of Mad3 in immature B cells induce Id2 expression, which inhibits transcription of genes essential for B cell differentiation.
identification as a novel target for regulation by E2F1 (显示 E2F1 ELISA试剂盒)
These studies support a novel role for Mad3 in cerebellar granule neuron precursors proliferation and possibly tumorigenesis.
Adenosine signaling mediates SUMO-1 (显示 SUMO1 ELISA试剂盒) modification of IkappaBalpha (显示 NFKBIA ELISA试剂盒) during hypoxia and reoxygenation.
This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.
MAX dimerization protein 3
, Max-associated protein 3
, Max-interacting transcriptional repressor MAD3
, class C basic helix-loop-helix protein 13
, max dimerization protein 3
, max dimerizer 3
, max-associated protein 3
, max-interacting transcriptional repressor MAD3