MAGE-Like 2 (MAGEL2) ELISA试剂盒

Prader-Willi syndrome (PWS) is caused by the loss of expression of imprinted genes in chromosome 15q11-q13 region. 再加上,我们可以发MAGE-Like 2 抗体 (45)MAGE-Like 2 蛋白 (2)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID
 MAGEL2 MAGEL2 54551
大鼠 MAGEL2 MAGEL2 679875
小鼠 MAGEL2 MAGEL2 27385

适于 MAGE-Like 2 相互作用对的更多 ELISA 试剂盒

Human MAGE-Like 2 (MAGEL2) interaction partners

  1. Immunohistochemistry using D2-40 monoclonal antibody (MAGE2) and anti-MITF1 increased detection of lymphovascular invasion in primary cutaneous melanoma.

  2. A similar pro (显示 LEP ELISA试剂盒)gressive loss of leptin sensitivity caused by loss of MAGEL2 in children with Prader-Willi s (显示 LEP ELISA试剂盒)yndrome could ex (显示 POMC ELISA试剂盒)plain the delayed onset of increased appetite and weight gain in this complex disorder.

  3. We find that MAGE-A2 interacts with MDM2 (显示 MDM2 ELISA试剂盒) via the N-terminal p53 (显示 TP53 ELISA试剂盒)-binding pocket and the RING finger (显示 PCGF1 ELISA试剂盒) domain of MDM2 (显示 MDM2 ELISA试剂盒) that is required for homo/hetero-dimerization and for E2 ligase interaction.

  4. Truncating Mutations of MAGEL2, a Gene within the Prader-Willi Locus, Are Responsible for Severe Arthrogryposis.

  5. Consistent with increased cell death, the induced loss of MAGEA2 expression correlated with increased caspase 3 (显示 CASP3 ELISA试剂盒)/7 activity, BCL2 (显示 BCL2 ELISA试剂盒)/BAX (显示 BAX ELISA试剂盒) ratio and TUNEL signal.

  6. MAGEA2 has a critical role in the development of tamoxifen-resistant breast cancer

  7. MAGEL2 is a new gene causing complex autism spectrum disorder and MAGEL2 loss of function can contribute to several aspects of the Prader-Willi syndrome phenotype.

  8. These findings provide a cellular and molecular function for MAGE-L2-TRIM27 (显示 RFP ELISA试剂盒) in retrograde transport, including an unappreciated role of K63-linked ubiquitination and identification of an activating signal of the WASH regulatory complex.

  9. MageA2 interferes with p53 (显示 TP53 ELISA试剂盒) acetylation at PML (显示 PML ELISA试剂盒)-nuclear bodies (NBs (显示 NBN ELISA试剂盒)) and with PMLIV-dependent activation of p53 (显示 TP53 ELISA试剂盒).

  10. Report MAGEA1 (显示 MAGEA1 ELISA试剂盒)-A6 expression in sputum suggests presence of lung cancer cells or precancerous cells.

Pig (Porcine) MAGE-Like 2 (MAGEL2) interaction partners

  1. Moreover, -712C>G and -708T>C had significant effects on MAGEL2 transcription and placental efficiency

  2. Imprinting analysis showed that NDN (显示 NDN ELISA试剂盒) and MAGEL2 are paternally expressed in all tissues of pig where the genes were expressed as in human and mouse.

Mouse (Murine) MAGE-Like 2 (MAGEL2) interaction partners

  1. these findings suggest that a loss of Magel2 leads to the disruption of hypothalamic feeding circuits, an effect that appears to be independent of the neurodevelopmental effects of leptin (显示 LEP ELISA试剂盒) and ghrelin (显示 GHRL ELISA试剂盒) and likely involves a direct neurotrophic effect of Magel2.

  2. Normal leptin (显示 LEP ELISA试剂盒) responses were found in Magel2-null mice up to 4 weeks of age, but the proportion of leptin (显示 LEP ELISA试剂盒)-responsive POMC (显示 POMC ELISA试剂盒) neurons was reduced in 6-week-old Magel2-null mice.

  3. Magel2 inactivation induces a deficit in social recognition and social interaction and a reduced learning ability in adult male mice.

  4. This neural defect, together with increased fat mass, blunted circadian rhythm, and growth hormone (显示 GH1 PLURAL_@44952@) response pathway defects that are also linked to loss of MAGEL2, could contribute to the hyperphagia and obesity that are hallmarks of this disorder.

  5. This study demonstrated that Magel2-null mice have abnormalities of hypothalamic endocrine axes that recapitulate phenotypes in Prader-Willi syndrome.

  6. Magel2-deficient mouse with 50% neonatal mortality had an altered onset of suckling activity and subsequent impaired feeding.

  7. Magel2 gene is imprinted, with preferential expression from the paternal allele in mouse and human.

  8. role of the circadian rhythm output gene Magel2 in brain structure and behavior

  9. necdin (显示 NDN ELISA试剂盒) and MAGE-G1 (显示 NDNL2 ELISA试剂盒) target both E2F1 (显示 E2F1 ELISA试剂盒) and p75 (显示 NGFR ELISA试剂盒) to regulate cell viability during brain development.

  10. Inactivation of the mouse Magel2 gene results in growth abnormalities similar to Prader-Willi syndrome

MAGE-Like 2 (MAGEL2) 抗原简介

Antigen Summary

This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This gene has two identical copies at different loci. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.

Gene names and symbols associated with MAGE-Like 2 (MAGEL2) ELISA试剂盒

  • MAGE-like 2 (MAGEL2) 抗体
  • MAGE-like protein 2 (LOC100343334) 抗体
  • MAGE-like 2 (Magel2) 抗体
  • melanoma antigen family A, 2 (MAGEA2) 抗体
  • melanoma antigen, family L, 2 (Magel2) 抗体
  • CT1.2 抗体
  • Mage-l2 抗体
  • MAGE2 抗体
  • MAGEA2A 抗体
  • MAGEL2 抗体
  • NDNL1 抗体
  • nM15 抗体
  • ns7 抗体

Protein level used designations for MAGE-Like 2 (MAGEL2) ELISA试剂盒

MAGE-like 2 , MAGE-like protein 2 , necdin-like protein 1 , protein nM15 , melanoma antigen-like gene 2 , melanoma antigen, family L, 2 , MAGE-2 antigen , cancer/testis antigen 1.2 , cancer/testis antigen family 1, member 2 , melanoma antigen 2 , melanoma-associated antigen 2 , necdin-like 1 , protein nS7

GENE ID SPECIES
719760 Macaca mulatta
100343334 Oryctolagus cuniculus
54551 Homo sapiens
100154924 Sus scrofa
538665 Bos taurus
679875 Rattus norvegicus
4101 Homo sapiens
27385 Mus musculus
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