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LNX1 encodes a membrane-bound protein that is involved in signal transduction and protein interactions. 再加上，我们可以发LNX1 蛋白 (4) 和 LNX1 试剂盒 (2)和数多这个蛋白质的别的产品。
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Human Polyclonal LNX1 Primary Antibody for ELISA - ABIN408672
Chen, Xu, Zhao, Hu, Cheng, Kang, Xie, Lu: Characterization of human LNX, a novel ligand of Numb protein X that is downregulated in human gliomas. in The international journal of biochemistry & cell biology 2005
Bozozok (Boz, also known as Dharma or Nieuwkoid) as a binding partner and substrate of Lnx-l.
the PDZ domain-containing protein (显示 USH1C 抗体) ligand-of-numb protein (显示 NUMBL 抗体)-X (LNX) is found in complex with the coxsackievirus and adenovirus receptor (显示 CXADR 抗体) (CAR)
LNX1 may play a role in regulating (显示 ERBB2 抗体) neuregulin-1/ErbB signaling in perisynaptic Schwann cells.
LNX1 provides an endocytic scaffold for JAM4 (显示 IGSF5 抗体) that is implicated in the reorganization of cell junctions.
LNX was closely related to human gliomas and suggested it plays an important role in gliomas by notch (显示 NOTCH1 抗体) signaling.
LNX1-mediated ubiquitination and degradation of PBK (显示 PBK 抗体) inhibited cell proliferation and enhanced sensitivity to doxorubicin-induced apoptosis.
identify and confirm six novel LNX1 binding partners: KCNA4 (显示 KCNA4 抗体), PAK6 (显示 PAK6 抗体), PLEKHG5 (显示 PLEKHG5 抗体), PKC (显示 PRRT2 抗体)-alpha1, TYK2 (显示 TYK2 抗体) and PBK (显示 PBK 抗体), and suggest that LNX1 functions as a signalling scaffold.
The authors found a high level of LNX1 and LNX2 mRNAs in endocarditis, the principal manifestation of chronic Q fever, but not in acute Q fever.
LNX1 and LNX2 interact with CD8alpha and promote its ubiquitylation and endocytosis
Down-regulation of LNX could result in cell cycle arrest in G0/G1 phase through inhibition of beta-catenin (显示 CTNNB1 抗体), MAPK (显示 MAPK1 抗体), NFkappaB (显示 NFKB1 抗体), c-Myc (显示 MYC 抗体)-dependent pathway and activation of p53 (显示 TP53 抗体), TGF-beta (显示 TGFB1 抗体)-dependent pathway.
LNX and RhoC (显示 RHOC 抗体) might be part of a larger protein complex that would have important functions in signaling transduction about regulating the transcriptional activities of AP-1 (显示 FOSB 抗体).
identifed ligand of Numb protein (显示 NUMBL 抗体) X as an Np9-interacting partner; findings point to the possibility that Np9 affects tumorigenesis through the LNX/Numb (显示 NUMB 抗体)/Notch (显示 NOTCH1 抗体) pathway
The presence of multiple protein binding domains involved in signal transduction and interaction with Numb (显示 NUMB 抗体) and SKIP suggested an important role for LNX in tumorogenesis.
The interaction of c-Src with LNX1 depends on the C-terminal PDZ ligand of c-Src.
This gene encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene, which is located on chromosome 17, has been identified for this gene.
ligand of numb-protein X 1
, multi-PDZ-domain-containing protein
, E3 ubiquitin-protein ligase LNX
, E3 ubiquitin-protein ligase LNX-like
, e3 ubiquitin-protein ligase LNX-like
, ligand of Numb protein X 1
, ligand of Numb-binding protein 1
, numb-binding protein 1
, PDZ domain-containing ring finger protein 2
, multi-PDZ-domain-containing protein, E3 ubiquitin-protein ligase LNX