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LRRK2 抗体

(Leucine-Rich Repeat Kinase 2 (LRRK2))
This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8. [provided by RefSeq, Jul 2008].
LRRK2 抗体  (AA 931-962) LRRK2 抗体  (AA 931-962) LRRK2 抗体 (AA 931-962) (ABIN3028794)

LRRK2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

LRRK2 抗体  (AA 930-961) LRRK2 抗体  (AA 930-961) LRRK2 抗体 (AA 930-961) (ABIN3031610)

LRRK2 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated

LRRK2 抗体  (AA 878-909) LRRK2 抗体  (AA 878-909) LRRK2 抗体 (AA 878-909) (ABIN3031607)

LRRK2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

LRRK2 抗体 by 适用

Find LRRK2 抗体 for a variety of species such as anti-Human LRRK2, anti-Mouse LRRK2, anti-Rat LRRK2. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find LRRK2 抗体 validated for a specific application such as WB, ELISA, IHC, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.

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Find LRRK2 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

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Find LRRK2 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular LRRK2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (5)
Cat. No. ABIN3028794
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IF
Validations
  • (5)
Cat. No. ABIN3031610
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (5)
Cat. No. ABIN3031607
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ICC, IP
Validations
  • (3)
Cat. No. ABIN7436534
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, FACS
Validations
  • (3)
Cat. No. ABIN6243251
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (4)
  • (3)
Cat. No. ABIN1882109
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF
Validations
  • (2)
  • (3)
Cat. No. ABIN391148
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (1)
  • (3)
Cat. No. ABIN391146
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7373744
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application
Validations
  • (2)
  • (2)
Cat. No. ABIN387804
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7321713
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB
Validations
  • (1)
  • (1)
Cat. No. ABIN387805
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN3031611
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN3031608
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (2)
Cat. No. ABIN7044716
Quantity 50 μL
Datasheet Datasheet

Latest Publications for our LRRK2 抗体

Bonello, Hassoun, Mouton-Liger, Shin, Muscat, Tesson, Lesage, Beart, Brice, Krupp, Corvol, Corti: "LRRK2 impairs PINK1/Parkin-dependent mitophagy via its kinase activity: pathologic insights into Parkinson's disease." in: Human molecular genetics, (2019) (PubMed).

Kim, Pajarillo, Rizor, Son, Lee, Aschner, Lee: "LRRK2 kinase plays a critical role in manganese-induced inflammation and apoptosis in microglia." in: PLoS ONE, Vol. 14, Issue 1, pp. e0210248, (2019) (PubMed).

Lim, Bang, Choi, Han, Kwon, Liu, Choi: "LRRK2 G2019S Induces Anxiety/Depression-like Behavior before the Onset of Motor Dysfunction with 5-HT1A Receptor Upregulation in Mice." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 38, Issue 7, pp. 1611-1621, (2019) (PubMed).

Hsieh, Li, Vanhauwaert, Nguyen, Davis, Bu, Wszolek, Wang: "Miro1 Marks Parkinson's Disease Subset and Miro1 Reducer Rescues Neuron Loss in Parkinson's Models." in: Cell metabolism, Vol. 30, Issue 6, pp. 1131-1140.e7, (2019) (PubMed).

Takanashi, Funayama, Matsuura, Yoshino, Li, Tsuyama, Takashima, Nishioka, Hattori: "Isolated nigral degeneration without pathological protein aggregation in autopsied brains with LRRK2 p.R1441H homozygous and heterozygous mutations." in: Acta neuropathologica communications, Vol. 6, Issue 1, pp. 105, (2018) (PubMed).

Nucifora, Nucifora, Ng, Arbez, Guo, Roby, Shani, Engelender, Wei, Wang, Li, Moore, Pletnikova, Troncoso, Sawa, Dawson, Smith, Lim, Ross: "Ubiqutination via K27 and K29 chains signals aggregation and neuronal protection of LRRK2 by WSB1." in: Nature communications, Vol. 7, pp. 11792, (2016) (PubMed).

López de Maturana, Lang, Zubiarrain, Sousa, Vázquez, Gorostidi, Águila, López de Munain, Rodríguez, Sánchez-Pernaute: "Mutations in LRRK2 impair NF-κB pathway in iPSC-derived neurons." in: Journal of neuroinflammation, Vol. 13, Issue 1, pp. 295, (2016) (PubMed).

Bliederhaeuser, Zondler, Grozdanov, Ruf, Brenner, Melrose, Bauer, Ludolph, Gillardon, Kassubek, Weishaupt, Danzer: "LRRK2 contributes to monocyte dysregulation in Parkinson's disease." in: Acta neuropathologica communications, Vol. 4, Issue 1, pp. 123, (2016) (PubMed).

Zhang, Li, Lu, Liu et al.: "Cerebral potential biomarkers discovery and metabolic pathways analysis of ?-synucleinopathies and the dual effects of Acanthopanax senticosus Harms on central nervous system through metabolomics ..." in: Journal of ethnopharmacology, Vol. 163, pp. 264-72, (2015) (PubMed).

Reyniers, Del Giudice, Civiero, Belluzzi, Lobbestael, Beilina, Arrigoni, Derua, Waelkens, Li, Crosio, Iaccarino, Cookson, Baekelandt, Greggio, Taymans: "Differential protein-protein interactions of LRRK1 and LRRK2 indicate roles in distinct cellular signaling pathways." in: Journal of neurochemistry, Vol. 131, Issue 2, pp. 239-50, (2015) (PubMed).

Aliases for LRRK2 抗体

leucine-rich repeat kinase 2 (lrrk2) 抗体
leucine rich repeat kinase 2 (LRRK2) 抗体
leucine-rich repeat kinase 2 (Lrrk2) 抗体
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