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LGALS9 was initially thought to represent a pseudogene of galectin 9; however, this transcript has good exon-intron structure and encodes a predicted protein of the same size as and highly similar to galectin 9. 再加上，我们可以发Lectin, Galactoside-Binding, Soluble, 9 试剂盒 (54) 和 Lectin, Galactoside-Binding, Soluble, 9 蛋白 (39)和数多这个蛋白质的别的产品。
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Mouse (Murine) Monoclonal LGALS9 Primary Antibody for FACS - ABIN2658314
Dunphy, Barcham, Bischof, Young, Nash, Meeusen: Isolation and characterization of a novel eosinophil-specific galectin released into the lungs in response to allergen challenge. in The Journal of biological chemistry 2002
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Mouse (Murine) Monoclonal LGALS9 Primary Antibody for FACS - ABIN2657895
Tsuboi, Abe, Nakagawa, Oomizu, Watanabe, Nishi, Nakamura, Yamauchi, Hirashima: Galectin-9 protects mice from the Shwartzman reaction by attracting prostaglandin E2-producing polymorphonuclear leukocytes. in Clinical immunology (Orlando, Fla.) 2007
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Human Monoclonal LGALS9 Primary Antibody for ELISA (Capture), FACS - ABIN1449219
Yanai, Saito, Kakinuma, Kon, Hirota, Taniguchi-Yanai, Nishijo, Shigematsu, Horiguchi, Kasuya, Sugiyama, Yagami, Murakami, Fukamizu: Renin-dependent cardiovascular functions and renin-independent blood-brain barrier functions revealed by renin-deficient mice. in The Journal of biological chemistry 2000
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Human Polyclonal LGALS9 Primary Antibody for EIA, WB - ABIN952439
Dardalhon, Anderson, Karman, Apetoh, Chandwaskar, Lee, Cornejo, Nishi, Yamauchi, Quintana, Sobel, Hirashima, Kuchroo: Tim-3/galectin-9 pathway: regulation of Th1 immunity through promotion of CD11b+Ly-6G+ myeloid cells. in Journal of immunology (Baltimore, Md. : 1950) 2010
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Human Monoclonal LGALS9 Primary Antibody for FACS - ABIN1449220
Lipkowitz, Leal-Pinto, Cohen, Abramson: Galectin 9 is the sugar-regulated urate transporter/channel UAT. in Glycoconjugate journal 2004
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Human Polyclonal LGALS9 Primary Antibody for ELISA, WB - ABIN561667
Bellac, Coimbra, Simon, Imboden, Leib: Gene and protein expression of galectin-3 and galectin-9 in experimental pneumococcal meningitis. in Neurobiology of disease 2007
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Mouse (Murine) Polyclonal LGALS9 Primary Antibody for FACS, ICC - ABIN4899254
Iqbal, Sampaio, Maione, Greco, Niki, Hirashima, Perretti, Cooper: Endogenous galectin-1 and acute inflammation: emerging notion of a galectin-9 pro-resolving effect. in The American journal of pathology 2011
Cow (Bovine) Polyclonal LGALS9 Primary Antibody for WB - ABIN2785903
Bi, Earl, Jacobs, Baum: Structural features of galectin-9 and galectin-1 that determine distinct T cell death pathways. in The Journal of biological chemistry 2008
Galectin 9 is a novel dectin 1 (显示 CLEC7A 抗体) ligand in pancreatic ductal adenocarcinoma. Upon disruption of the dectin 1 (显示 CLEC7A 抗体)-galectin 9 axis, CD4 (显示 CD4 抗体)(+) and CD8 (显示 CD8A 抗体)(+) T cells, which are dispensable for PDA progression in hosts with an intact signaling axis, become reprogrammed into indispensable mediators of anti-tumor immunity.
The Gal-9/Tim-3 (显示 HAVCR2 抗体) signal is important for the regulation of decidua NK cells function, which is beneficial for the maintenance of a normal pregnancy.
These results indicate the possibility that cooperative binding of oligosaccharide and neighboring polypeptide structures of monoclonal IgE to galectin-9 affects the overall affinity and specificity of the IgE-lectin interaction.
galectin-9 functions as a novel alarmin by augmenting the inflammatory response in sepsis development during pulmonary F. novicida infection.
Gal-9 has a role in the maintenance of hepatic homeostasis and preventing liver ischemia-reperfusion injury
Gal-9, a natural TIM-3 (显示 HAVCR2 抗体) ligand, was produced primarily by and released from ischemia-reperfusion-stressed hepatocytes, both in vivo and in vitro.
Galectin-9 functions as an astrocyte-microglia communication signal and promotes cytokine production from microglia in a Tim-3 (显示 HAVCR2 抗体) independent manner.
galectin-9, in addition to being an effector molecule for regulatory T cells cells, acts synergistically with TGF-beta (显示 TGFB1 抗体) to enforce iTreg cell differentiation and maintenance.
Galectin-9 is a suppressor of T and B cells and predicts the immune modulatory potential of mesenchymal stromal cell preparations.
action of agonist anti-4-1BB (显示 TNFRSF9 抗体) in suppressing autoimmune and allergic inflammation was completely dependent on Galectin-9 (Gal-9). Gal-9 directly bound to 4-1BB (显示 TNFRSF9 抗体), in a site distinct from the binding site of antibodies and the natural ligand of 4-1BB (显示 TNFRSF9 抗体)
X-ray structure of a protease-resistant mutant form of human galectin-9 having two carbohydrate recognition domains with a metal-binding site has been presented.
These findings may indicate that an increase in the Gal-9 level, a novel immune checkpoint molecule, can reflect immune-related adverse effects of various biotherapies.
Our data suggest a role of galectin-9 in regulating HIV transcription and viral production in vivo during therapy
these data suggest that the high Tim-3 (显示 HAVCR2 抗体) expression in monocytes could be utilized by tumor-promoting Gal-9 expression on CD4 (显示 CD4 抗体)(+) T cells
this study shows that in osteosarcoma patients, Tim3 (显示 HAVCR2 抗体) expression did not directly mediate immune suppression, but the interaction between Tim3 (显示 HAVCR2 抗体)+ T cells and monocytes, naive CD4 (显示 CD4 抗体)+ T cells, and Gal9-expressing CD4 (显示 CD4 抗体)+ CD25 (显示 IL2RA 抗体)+ Tregs could resulting in progressive suppression of Th1 (显示 TH1L 抗体) responses
The human recombinant galectin-9 has demonstrated anti-cancer activities, including inducing apoptosis in hematological, dermatological and gastrointestinal malignancies. In this review, the molecular characteristics, history and apoptosis-inducing potential of galectin-9 are described. [review]
Results showed that in acute febrile phase, galectin-9 and galectin-3BP were induced in dengue patients compared to healthy controls suggesting that both molecules might be important inflammatory mediators in acute dengue virus infection.
In this review, we summarize the latest knowledge on the structure, receptors, cellular targets, trafficking pathways and functional properties of galectin-9 and discuss how galectin-9-mediated signalling cascades can be exploited in cancers and immunotherapies
this study shows that the levels of expression of Gal-9 on CD4 (显示 CD4 抗体)+ T cells, CD8 (显示 CD8A 抗体)+ T cells, CD56 (显示 NCAM1 抗体)+ T cells and in serum in patients with systemic lupus erythematosus are significantly higher than those of healthy controls
The Tim-3 (显示 HAVCR2 抗体)/Gal-9 pathway might link disease progression with T cell exhaustion during bovine leukemia virus infection.
The relative abundance of PIBF (显示 PIBF1 抗体), LGALS1 (显示 LGALS1 抗体), LGALS3 (显示 LGALS2 抗体), LGALS3BP (显示 LGALS3BP 抗体), and LGALS9 mRNA would display a differential expression pattern in the endometrium.
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene.
lectin, galactoside-binding, soluble, 9
, galactoside-binding soluble lectin 9
, galectin 9
, lectin, galactoside-binding, soluble, 9 (galectin 9)
, lectin, galactose binding, soluble 5
, tumor antigen HOM-HD-21
, urate transporter/channel protein
, 36 kDa beta-galactoside-binding lectin
, Lectin galactose binding soluble 9 (Galectin-9)
, Lectin, galactose binding, soluble 9 (Galectin-9)
, urate transporter/channel
, urate transporter
, urate transporter/channel protein, isoform (UATp,i)