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LAMB2 蛋白

(Laminin, beta 2 (Laminin S) (LAMB2))
Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins, composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively), form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the beta chain isoform laminin, beta 2. The beta 2 chain contains the 7 structural domains typical of beta chains of laminin, including the short alpha region. However, unlike beta 1 chain, beta 2 has a more restricted tissue distribution. It is enriched in the basement membrane of muscles at the neuromuscular junctions, kidney glomerulus and vascular smooth muscle. Transgenic mice in which the beta 2 chain gene was inactivated by homologous recombination, showed defects in the maturation of neuromuscular junctions and impairment of glomerular filtration. Alternative splicing involving a non consensus 5' splice site (gc) in the 5' UTR of this gene has been reported. It was suggested that inefficient splicing of this first intron, which does not change the protein sequence, results in a greater abundance of the unspliced form of the transcript than the spliced form. The full-length nature of the spliced transcript is not known. [provided by RefSeq, Aug 2011].
LAMB2 Protein (AA 1498-1716) (His tag) (ABIN7404077)

LAMB2 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % SDS, WB, Imm, PC

LAMB2 Protein (AA 1176-1309) (His tag) (ABIN7401872)

LAMB2 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % SDS, WB, Imm, PC

LAMB2 Protein (AA 38-350) (His tag,GST tag) (ABIN7395851)

LAMB2 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % SDS, WB, Imm, PC

LAMB2 蛋白 by Origin

Find LAMB2 蛋白 for a variety of species such as anti-Human LAMB2, anti-Mouse LAMB2, anti-Rat LAMB2. The species listed below are among those available. Click on a link to go to the corresponding products.

LAMB2 蛋白 by Source

Here you will find LAMB2 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

LAMB2 蛋白 by 蛋白类型

Here you can find LAMB2 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

LAMB2 蛋白 by 应用范围

Find LAMB2 蛋白 validated for a specific application such as SDS, WB, Imm, PC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular LAMB2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7404077
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7401872
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7395851
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7414516
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7414513
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7414519
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5712898
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3010414
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2724491
Quantity 20 μg
Datasheet Datasheet

Aliases for LAMB2 蛋白

laminin subunit beta 2 (LAMB2) 蛋白
laminin, beta 2 (Lamb2) 蛋白
laminin subunit beta 2 (Lamb2) 蛋白
laminin subunit beta 2 L homeolog (lamb2.L) 蛋白
laminin, beta 2 (laminin S) (LAMB2) 蛋白
AW211941 蛋白
Lamb-2 蛋白
lamb1 蛋白
LAMC1 蛋白
laminin 蛋白
LAMS 蛋白
Lams 蛋白
lams 蛋白
NPHS5 蛋白
SLAM 蛋白
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