Lactate Dehydrogenase B 蛋白 (LDHB)

LDHB encodes an enzyme which catalyzes the reversible conversion of lactate and pyruvate, and NAD and NADH, in the glycolytic pathway. 再加上,我们可以发Lactate Dehydrogenase B 抗体 (146)Lactate Dehydrogenase B 试剂盒 (37)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
LDHB 3945 P07195
LDHB 16832 P16125
LDHB 24534 P42123
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Showing 10 out of 44 products:

产品编号 Origin 资源 标记 图像 规格 供应商 交付 价格 详细
Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
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Insect Cells 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
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大肠杆菌(E. Coli) His tag Lactate Dehydrogenase B (LDHB) (AA 2-334), (full length) protein (His tag) 50 μg Log in to see 13至16个工作日
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大肠杆菌(E. Coli) His tag 100 μg Log in to see 2至3个工作日
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大肠杆菌(E. Coli) His tag 100 μg Log in to see 15至19个工作日
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小麦胚 GST tag 10 μg Log in to see 11至12个工作日
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大肠杆菌(E. Coli) His tag Validation with Western Blot 10 μg Log in to see 12至15个工作日
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大肠杆菌(E. Coli) His tag   50 μg Log in to see 4 Days
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大肠杆菌(E. Coli) His tag   50 μg Log in to see 11 Days
$341.00
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大肠杆菌(E. Coli) 小鼠 His tag 100 μg Log in to see 15至18个工作日
$560.00
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LDHB 蛋白 by Origin and Source

Origin 在表达 标记
Human , , , ,
, ,
Mouse (Murine) ,

Rat (Rattus) ,

引用最多的Lactate Dehydrogenase B 蛋白

  1. Human LDHB Protein expressed in Wheat germ - ABIN1309269 : Liu, He, Xie, Su, Teitz-Tennenbaum, Sabel, Lubman: Serum autoantibody profiling using a natural glycoprotein microarray for the prognosis of early melanoma. in Journal of proteome research 2010 (PubMed)

更多Lactate Dehydrogenase B (LDHB)互动伙伴

Pig (Porcine) Lactate Dehydrogenase B (LDHB) interaction partners

  1. The NADH-cofactor binding site of pig heart LDH is involved in the interaction with acidic phospholipids, in the pig skeletal muscle LDH, neither the cofactor binding site nor the subunit interfacing areas seem to be involved in the interaction.

Horse (Equine) Lactate Dehydrogenase B (LDHB) interaction partners

  1. Molecular characterization and expression pattern of the equine lactate dehydrogenase B genes

Human Lactate Dehydrogenase B (LDHB) interaction partners

  1. this study shows that low base line lactate dehydrogenase is linked with a better tumor response, and that prolonged overall survival and progression-free survival are observed for patients under ipilimumab treatment with no increase in lactate dehydrogenase

  2. our study examines the inclusion of salivary LDH as potential diagnostic parameter and therapeutic index in Oral squamous cell carcinoma

  3. addition of exogenous lactic acid to growth media was sufficient to induce cell death that could be inhibited by the expression of LDHB. the results suggest that lactate dehydrogenase is a general suppressor of programmed cell death in yeast.

  4. The aim of this study was to demonstrate the effects of 6-week low-intensity training on changes in indicators of aerobic capacity and on HSPA1A (显示 HSPA1A 蛋白), HSPB1 (显示 HSPB1 蛋白), and LDHb expression in white blood cells in high level rowers.

  5. Lactate dehydrogenase B is associated with the response to neoadjuvant chemotherapy in oral squamous cell carcinoma.

  6. The readthrough-extended lactate dehydrogenase subunit LDHBx can also co-import LDHA, the other LDH subunit, into peroxisomes.

  7. In this study, we inhibited LDH using oxamate resulting in the inhibition of proliferation and induction of apoptosis in gastric cancer

  8. We were able to provide evidence that methylation of HLTF and especially HPP1 detected in serum is strongly correlated with cell death in CRC using LDH as surrogate marker

  9. This meta-analysis shows that high serum LDH level is obviously associated with lower overall survival rate in patients with osteosarcoma, and it is an effective biomarker of prognosis.

  10. These observations support prospective clinical evaluation of LDHB as a predictive marker of response for patients with breast cancer receiving neoadjuvant chemotherapy.

Mouse (Murine) Lactate Dehydrogenase B (LDHB) interaction partners

  1. these results identified a previously unrecognized Ldhb-driven alteration in muscle mitochondrial function and suggested a mechanism for the adaptive metabolic response induced by exercise training.

  2. Findings suggest that RANKL protein-induced lactate dehydrogenase (LDH) activation stimulates glycolytic and mitochondrial respiratory metabolism via transcription factor NFATc1 signaling.

  3. drs (显示 SRPX 蛋白) regulates glucose metabolism via LDH-B. Downregulating drs (显示 SRPX 蛋白) may contribute to the Warburg effect, which is closely associated with malignant progression of cancer cells.

  4. Exercise-induced changes in tumour LDH-B and MCT1 (显示 MCTS1 蛋白) expression are modulated by oestrogen-related receptor alpha in breast cancer-bearing BALB/c mice

  5. Data show that PI3K/Akt (显示 AKT1 蛋白) signalling pathway and lactate dehydrogenase (LDH) play a crucial role in increase of cardiac ATP-binding cassette transporter sub-family C member 9 (SUR2A (显示 ABCC9 蛋白)) induced by in vivo exposure to 18% oxygen.

  6. PGC-1alpha in skeletal muscle drives the expression of lactate dehydrogenase (LDH) B in an estrogen-related receptor-alpha-dependent manner.

  7. the Ldhb gene, which encodes the H isoform of lactate dehydrogenase, as a robust PPARgamma (显示 PPARG 蛋白) target in trophoblasts.

  8. findings offer proof of concept for targeting LDHB as a therapeutic strategy in cancers driven by aberrant activation of the RTK-PI3K-AKT (显示 AKT1 蛋白)-mTOR (显示 FRAP1 蛋白) signaling cascade

  9. The increased LDH-A (显示 LDHA 蛋白)/LDH-B ratio causes high brain lactate levels, which, in turn, are predictive of aging phenotypes.

  10. beta-agonists increased serum LDH levels, but it was not due to release from the heart.

蛋白简介Lactate Dehydrogenase B (LDHB)

蛋白简介

This gene encodes an enzyme which catalyzes the reversible conversion of lactate and pyruvate, and NAD and NADH, in the glycolytic pathway. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on the X chromosome and on chromosome. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene names and symbols associated with Lactate Dehydrogenase B 蛋白 (LDHB)

  • lactate dehydrogenase B (ldhb)
  • lactate dehydrogenase B pseudogene (LOC407246)
  • lactate dehydrogenase B (LDHB)
  • lactate dehydrogenase B-like (LOC718082)
  • lactate dehydrogenase B (Ldhb)
  • lactate dehydrogenase B S homeolog (ldhb.S)
  • AI790582 蛋白
  • H-Ldh 蛋白
  • Ldh-2 蛋白
  • LDH-B 蛋白
  • LDH-H 蛋白
  • ldh2 蛋白
  • ldhb 蛋白
  • ldhba 蛋白
  • LDHBD 蛋白
  • TRG-5 蛋白

Protein level used designations for Lactate Dehydrogenase B 蛋白 (LDHB)

L-lactate dehydrogenase B , L-lactate dehydrogenase B chain , LDH heart subunit , LDH-B , LDH-H , lactate dehydrogenase B , lactate dehydrogenase H chain , renal carcinoma antigen NY-REN-46 , lactate dehydrogenase 2, B chain , lactate dehydrogenase-B , Lactate dehydrogenease B , lactate dehydrogenase-H

GENE ID SPECIES
394477 Xenopus (Silurana) tropicalis
407246 Sus scrofa
554182 Monodelphis domestica
706110 Macaca mulatta
718082 Macaca mulatta
100033997 Equus caballus
100587841 Nomascus leucogenys
3945 Homo sapiens
16832 Mus musculus
24534 Rattus norvegicus
281275 Bos taurus
100621540 Sus scrofa
100009106 Oryctolagus cuniculus
373997 Gallus gallus
380546 Xenopus laevis
100714853 Cavia porcellus
465337 Pan troglodytes
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