LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) ELISA试剂盒

The protein encoded by LIMS1 is an adaptor protein which contains five LIM domains, or double zinc fingers. 再加上,我们可以发LIM and Senescent Cell Antigen-Like Domains 1 抗体 (55)LIM and Senescent Cell Antigen-Like Domains 1 蛋白 (5)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
LIMS1 3987 P48059
大鼠 LIMS1 LIMS1 499443  
小鼠 LIMS1 LIMS1 110829 Q99JW4

antibodies-online.cn销售最多的LIM and Senescent Cell Antigen-Like Domains 1 ELISA试剂盒

Showing 1 out of 1 products:

产品编号 适用 灵敏度 范围 图像 规格 供应商 交付 价格 详细
0.056 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 7至10个工作日
¥3,820.64
详细

适于 LIM and Senescent Cell Antigen-Like Domains 1 相互作用对的更多 ELISA 试剂盒

Human LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) interaction partners

  1. Mammalian cells have two functional PINCH proteins, PINCH1 and PINCH2 (显示 LIMS2 ELISA试剂盒). PINCH not only binds to Nck2 and engages in the signaling of growth factor receptors, but also forms a ternary complex with ILK (显示 ILK ELISA试剂盒) and parvin (显示 PARVA ELISA试剂盒) (IPP (显示 IPP ELISA试剂盒) complex).

  2. our data suggest an essential role of PINCH1, ILK (显示 ILK ELISA试剂盒) and ILKAP (显示 ILKAP ELISA试剂盒) for the radioresistance of p53 (显示 TP53 ELISA试剂盒)-wildtype glioblastoma multiforme cells

  3. Data suggest that PINCH1 and Nck2 critically participate in the regulation of cellular radiosensitivity and EGFR (显示 EGFR ELISA试剂盒) function and downstream signaling in a cellular model of human squamous cell carcinoma.

  4. Downregulation of PINCH1 is associated with metastatic breast cancer.

  5. changes in CSF (显示 CSF2 ELISA试剂盒) levels of PINCH appear to correlate with changes in blood CD4 (显示 CD4 ELISA试剂盒) count and with changes in CSF (显示 CSF2 ELISA试剂盒) hyperphosphorylated Tau levels

  6. two novel genes, galectin 9 (显示 LGALS9 ELISA试剂盒) and PINCH, were expressed at much higher levels in cancerous lesions than in normal tissues in all the patients with clear-cell carcinoma who were examined

  7. PINCH predicts survival in rectal cancer patients with RT, but not in patients without RT. The expression of PINCH may be regulated by radiation and by environmental factors surrounding the cells.

  8. PINCH is increased and binds to hp-Tau. These studies address a new mechanism by which AD and HIV may intersect and identify PINCH as a contributing factor to the accumulation of hyperphosphorylated Tau.

  9. Pinch-1 mRNA and protein were significantly up-regulated in acute lymphoblastic leukemia and acute myeloid leukemia (显示 BCL11A ELISA试剂盒) bone marrow stromal cells compared to normal bone marrow stromal cells (p<0.01).

  10. PINCH protein might play an important role in the tumourigenesis and metastasis of gastric adenocarcinoma.

Mouse (Murine) LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) interaction partners

  1. findings suggest that PINCH-1 regulates integrin-mediated adhesion of keratinocytes through the interactions with ILK (显示 ILK ELISA试剂盒) as well as EPLIN (显示 LIMA1 ELISA试剂盒).

  2. Rsu-1 (显示 RSU1 ELISA试剂盒) expression is dramatically decreased in PINCH double knockout mouse livers.

  3. PINCH is increased and binds to hp-Tau. These studies address a new mechanism by which AD and HIV may intersect and identify PINCH as a contributing factor to the accumulation of hyperphosphorylated Tau.

  4. PINCH-1 inhibits JNK (显示 MAPK8 ELISA试剂盒)-mediated apoptosis by stabilising the PINCH-1 binding protein RSU-1 (显示 RSU1 ELISA试剂盒) and promotes Bcl-2 (显示 BCL2 ELISA试剂盒)-dependent pro-survival signalling downstream of integrins.

  5. Data suggest that the adapter protein (显示 GRB10 ELISA试剂盒) PINCH1 critically participates in the regulation of the cellular radiosensitivity of normal and malignant cells similarly under adhesion and suspension conditions.

  6. PINCH1 plays an essential role in early murine embryonic development but is dispensable in ventricular cardiomyocytes.

  7. These results provide important evidence for a crucial role of the PINCH-1-ILK (显示 ILK ELISA试剂盒)-alpha-parvin (显示 PARVA ELISA试剂盒) complex in the control of podocyte adhesion, morphology, and survival.

  8. LIM (显示 PDLIM5 ELISA试剂盒) 5 domain of PINCH1 interacts with Rsu-1 (显示 RSU1 ELISA试剂盒) in mammalian cells and functions, in part, by altering cell adhesion.

  9. The PINCH1 is composed of 5 LIM domains, binds ILK and locates to integrin-mediated adhesion sites, and PINCH1 is for integrin function, actin organization, cell-cell adhesion and endodermal cell survival during the implanting of mouse embryos.

  10. PICH1, Ilk (显示 ILK ELISA试剂盒) and alpha-parvin (显示 PARVA ELISA试剂盒) form a complex to costameres in neonatal mouse ventricular myocytes. This complex is stimulated by fibronectins and phenylephrine, and by both by drug synergism, to regulate cardiac myocyte hypertrophy.

LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) 抗原简介

Antigen Summary

The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with LIMS1

  • LIM and senescent cell antigen-like domains 1 (LIMS1) 抗体
  • LIM and senescent cell antigen-like domains 1 (Lims1) 抗体
  • 2310016J22Rik 抗体
  • 4921524A02Rik 抗体
  • AI507642 抗体
  • AU021743 抗体
  • AW551584 抗体
  • C430041B13Rik 抗体
  • Lims1l 抗体
  • LIMS3 抗体
  • LIMS3L 抗体
  • PINCH 抗体
  • PINCH-1 抗体
  • Pinch1 抗体
  • RGD1560732 抗体

Protein level used designations for LIMS1

LIM and senescent cell antigen-like-containing domain protein 1 , particularly interesting new Cys-His protein 1 , renal carcinoma antigen NY-REN-48

GENE ID SPECIES
3987 Homo sapiens
499443 Rattus norvegicus
414880 Gallus gallus
474540 Canis lupus familiaris
100511559 Sus scrofa
540281 Bos taurus
110829 Mus musculus
LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1) ELISA试剂盒 精选生产商
您还需要查找其他产品吗?