anti-LIM Domain Kinase 2 (LIMK2) 抗体

There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. 再加上,我们可以发LIMK2 蛋白 (10)LIMK2 试剂盒 (7)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
LIMK2 3985 P53671
LIMK2 29524 P53670
LIMK2 16886 O54785
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antibodies-online.cn销售最多的anti-LIMK2 抗体

Showing 10 out of 139 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain, using LIMK2 (Phospho-Ser283) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2至3个工作日
$302.50
详细
非结合性 WB 100 μg Log in to see 4至6个工作日
$240.00
详细
非结合性 ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: LIM kinase 2 Antibody [NBP1-85783] - Staining of human cell line U-251MG shows positivity in cytoplasm & mitochondria. Western Blot: LIM kinase 2 Antibody [NBP1-85783] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp 0.1 mL Log in to see 10至13个工作日
$439.69
详细
非结合性 ELISA, WB Western blot analysis of extracts from NIH-3T3 cells, treated with PMA 125ng/ml 30', using LIMK2 (Ab-283) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2至3个工作日
$302.50
详细
非结合性 ELISA, WB Western blot analysis of extracts from NIH-3T3 cells, treated with UV, using LIMK2 (Ab-505) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2至3个工作日
$302.50
详细
非结合性 IF, IHC, ELISA, WB Western blot analysis of extracts from HepG2/HuvEc cells, using LIMK2 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human heart tissue, using LIMK2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2至3个工作日
$302.50
详细
非结合性 IHC, ELISA, WB Western blot analysis of extracts from COLO205 cells, using LIMK2 (Phospho-Thr505) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using LIMK2 (Phospho-Thr505) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2至3个工作日
$302.50
详细
非结合性 IF, IHC (p), WB 0.1 mL Log in to see 6至8个工作日
$368.50
详细
非结合性 ICC, IF, IHC (p), IHC, WB Immunohistochemical analysis of paraffin- embedded human breast carcinoma tissue using LIMK2 (phospho-Thr505) antibody Western blot analysis of extract from NIH/3T3 cells treated or untreated with UV (60min), using LIMK2 (phospho- Thr505) antibody 0.05 mL Log in to see 7至9个工作日
$381.94
详细
山羊 非结合性 ELISA, WB   100 μg Log in to see 6至7个工作日
$326.89
详细

通过反应活性、应用领域、克隆类型和共轭标记 LIMK2 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-LIMK2 抗体

  1. Human Polyclonal LIMK2 Primary Antibody for IHC - ABIN966487 : Ohashi, Nagata, Maekawa, Ishizaki, Narumiya, Mizuno: Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop. in The Journal of biological chemistry 2000 (PubMed)
    Show all 3 Pubmed References

  2. Human LIMK2 Primary Antibody for IHC - ABIN966486 : Soosairajah, Maiti, Wiggan, Sarmiere, Moussi, Sarcevic, Sampath, Bamburg, Bernard: Interplay between components of a novel LIM kinase-slingshot phosphatase complex regulates cofilin. in The EMBO journal 2005 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal LIMK2 Primary Antibody for ICC, IF - ABIN4330985 : Kim, Ryu, Kim, Kang: LIM kinase-2 induces programmed necrotic neuronal death via dysfunction of DRP1-mediated mitochondrial fission. in Cell death and differentiation 2014 (PubMed)
    Show all 2 Pubmed References

更多抗LIMK2的相互作用对抗体

Human LIM Domain Kinase 2 (LIMK2) interaction partners

  1. these results suggested that TUG1 mediates cell growth and chemoresistance of SCLC by regulating LIMK2b via EZH2 (显示 EZH2 抗体).

  2. LIMK2 (rs149034313) is associated with Behcet's disease. The LIMK2 association is a missense variant with predicted protein damage that may influence functional interactions with proteins involved in cytoskeletal regulation by Rho GTPase (显示 RACGAP1 抗体), inflammation mediated by chemokine (显示 CCL1 抗体) and cytokine signaling pathways, T cell activation, and angiogenesis.

  3. We observed marked increases in LIM kinase 2 (LIMK2) and cofilin 1 (CFL1 (显示 CFL1 抗体)) gene expressions in metabolic syndrome patients.

  4. This study showed that LIMK2 messenger RNA levels was significantly upregulated in subjects with schizophrenia in laminar and cellular samples.

  5. Actin remodelling factor LIMK2 is a key player in the ciliogenesis control network in which YAP (显示 YAP1 抗体)/TAZ (显示 TAZ 抗体) and directional vesicle trafficking are integral components.

  6. Results show that in addition to a potential role in promoting metastasis, changes in LIMK1 (显示 LIMK1 抗体) and LIMK2 expression and/or activity might contribute to AR function in prostate cancer via regulation of microtubule cytoskeletal dynamics.

  7. results highlight the exciting possibility of combining specific LIMK2 inhibitors with anticancer drugs in the treatment of multi-drug resistant cancers

  8. LIMK2 expression was reduced in intestinal tumours of cancer-prone mice and in human colorectal cancer cell lines and tumours. LIMK2 expression progressively decreased with advancing stage of colorectal cancer.

  9. Overexpression of LIMK2 is associated with breast cancer growth and invasiveness.

  10. Nf1/LIMK2 interaction and inhibition allows to directly connect neurofibromatosis type I to actin cytoskeleton remodeling.

Mouse (Murine) LIM Domain Kinase 2 (LIMK2) interaction partners

  1. These data suggest that osteoblasts can increase their mechanosensitivity under continuous mechanical stimulation by reducing the actin stress fiber formation through inhibiting the LIMK2 expression.

  2. LIMK2 expression was reduced in intestinal tumours of cancer-prone mice.

  3. LIMK2 activity is required for keratinocyte migration in the developing eyelid.

  4. Using RNAi against LIMK2 to inhibit the cytoskeleton reorganization can promote the expression of c-fos gene and thus enhance the mechanosensitivity of c-fos gene in osteoblasts.

  5. Results suggest that constitutive activation of the Rho-ROCK-LIM (显示 PDLIM5 抗体) kinase pathway by extracellular production of lysophosphatidic acid by the action of autotaxin (显示 ENPP2 抗体) is required to maintain the large size of lysosomes in visceral endoderm cells.

  6. LIMK-1 (显示 LIMK1 抗体)/2 double knockout mice were more severely impaired in both ADF/cofilin (显示 CFL1 抗体) phosphorylation and excitatory synaptic function in the CA1 (显示 CA1 抗体) region of the hippocampus.

  7. a novel pathway emanating from the TGF-beta type I receptor (显示 TGFBR1 抗体) and leading to regulation of actin assembly, via the kinase LIMK2.

LIMK2 抗原简介

蛋白简介

There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. The protein encoded by this gene is phosphorylated and activated by ROCK, a downstream effector of Rho, and the encoded protein, in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. It is thought that this pathway contributes to Rho-induced reorganization of the actin cytoskeleton. At least three transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with anti-LIM Domain Kinase 2 (LIMK2) 抗体

  • LIM domain kinase 2 L homeolog (limk2.L) 抗体
  • LIM domain kinase 2 (limk2) 抗体
  • LIM domain kinase 2 (LIMK2) 抗体
  • LIM domain kinase 2 (Limk2) 抗体
  • LIM motif-containing protein kinase 2 (Limk2) 抗体
  • 9430059K01 抗体
  • A930024P04Rik 抗体
  • C85310 抗体
  • LIMK 抗体
  • LIMK2 抗体
  • Limk2a 抗体
  • Limk2b 抗体
  • Link2 抗体
  • wu:fa97c09 抗体
  • wu:fk73e11 抗体
  • xlimk2 抗体
  • zgc:91990 抗体

Protein level used designations for anti-LIM Domain Kinase 2 (LIMK2) 抗体

XLIM-Kinases2 , LIM domain kinase 2 , LIM domain kinase 2-like , LIM motif-containing protein kinase 2 , LIMK-2 , LIM kinase 2 , LIM-containing protein kinase 2a , LIM-containing protein kinase 2t , Limk2t-1 and Limk2t-2

GENE ID SPECIES
398298 Xenopus laevis
436924 Danio rerio
486363 Canis lupus familiaris
100058419 Equus caballus
100216249 Xenopus (Silurana) tropicalis
100223808 Taeniopygia guttata
100396965 Callithrix jacchus
100586214 Nomascus leucogenys
458970 Pan troglodytes
716614 Macaca mulatta
100478557 Ailuropoda melanoleuca
3985 Homo sapiens
29524 Rattus norvegicus
513539 Bos taurus
396010 Gallus gallus
16886 Mus musculus
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