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KIF5A encodes a member of the kinesin family of proteins. 再加上，我们可以发Kinesin Family Member 5A 试剂盒 (9) 和 Kinesin Family Member 5A 蛋白 (8)和数多这个蛋白质的别的产品。
Showing 10 out of 64 products:
Cow (Bovine) Polyclonal KIF5A Primary Antibody for IHC, WB - ABIN2778166
Reid, Kloos, Ashley-Koch, Hughes, Bevan, Svenson, Graham, Gaskell, Dearlove, Pericak-Vance, Rubinsztein, Marchuk: A kinesin heavy chain (KIF5A) mutation in hereditary spastic paraplegia (SPG10). in American journal of human genetics 2002
Human Polyclonal KIF5A Primary Antibody for EIA, IF - ABIN500118
Hirokawa: mRNA transport in dendrites: RNA granules, motors, and tracks. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2006
Deletion of a kinesin I motor unmasks a mechanism of homeostatic axon-branching control by neurotrophin-3 (显示 NTF3 抗体).
Our results shed light on Kinesin complexity and reveal determinants of specific Kif5A functions in mitochondrial transport, adaptor binding, and axonal maintenance.
De novo stop-loss frameshift variants in KIF5A result in a novel phenotype that includes severe infantile onset myoclonus, hypotonia, optic nerve abnormalities, dysphagia, apnea, and early developmental arrest.
KIF5A p.Ser974fs de novo mutation associated with myoclonic seizures and neonatal onset progressive leukoencephalopathy.
Zinc ion-mediated inhibition of KIF5A activity might be one molecular cause contributing to impaired transport processes within brain and other organs in cases of zinc dyshomeostasis.
This report describes the first known Asian family with a KIF5A mutation and broadens the clinical and electrophysiological spectrum associated with KIF5A-SPG10 mutations.
study describes 2 Spanish families with an adult onset complicated autosomal dominant hereditary spastic paraplegia with a mild sensory neuropathy; identified 2 novel mutations c.773 C>T and c.833 C>T in the KIF5A gene resulting in the P258L and P278L substitutions; both were located in the highly conserved kinesin motor domain of the protein
Kinesin-14 blocks microtubule nucleation in yeast and reveal that this inhibition is countered by the kinesin-5 protein, Cut7.[Cut7, Pkl1]
the novel mutation p.Leu259Gln in two siblings affected by Hereditary spastic paraplegia (HSP) complicated by deafness and in their father with a pure form of HSP.
Combining next-generation sequencing and conventional sequencing, study confirms that KIF5A mutations can cause variable phenotypes ranging from hereditary spastic paraplegia to Charcot-Marie-Tooth disease type 2
Conformations of microtubule-bound human kinesin-5 motor domain were visualised at successive steps in its ATPase (显示 DNAH8 抗体) cycle.
A review of the mechanism of pathogenesis involved in spastic paraplegia type 10 when KIF5A is inactivated by mutations.
Data suggest that KIF5 regulates gephyrin (显示 GPHN 抗体) sorting by a mechanism that involves GSK3 (显示 GSK3b 抗体) activity.
KIF5-SNPH (显示 SNPH 抗体) interaction mediates activity-induced immobilization of axonal mitochondria.
Found a role of KIF5A in process outgrowth and axonal transport of mitochondria, affecting motor neurons more severely than sensory neurons.
Expression of Kif5a in the mouse prefrontal cortex is modulated by a sequence variant (B2 SINE indel) in the 3' UTR (显示 UTS2R 抗体) of Comt (catechol-O-methyltransferase (显示 COMT 抗体)).
Data suggest that kinesin-1A is the principal anterograde motor for neurofilaments, that there may be functional redundancy among isoforms in neurofilament transport, and that anterograde and retrograde neurofilament motors are tightly coordinated.
assessement of the kinetics of the dystrobrevin (显示 DTNA 抗体)-Kif5A interaction suggesting that the tertiary structure of dystrobrevin (显示 DTNA 抗体) may play a role in regulating its interaction with Kif5a
This gene encodes a member of the kinesin family of proteins. Members of this family are part of a multisubunit complex that functions as a microtubule motor in intracellular organelle transport. Mutations in this gene cause autosomal dominant spastic paraplegia 10.
kinesin family member 5A
, kinesin heavy chain isoform 5A-like
, KIF5A variant protein
, kinesin heavy chain isoform 5A
, kinesin heavy chain neuron-specific 1
, kinesin, heavy chain, neuron-specific
, neuronal kinesin heavy chain
, Kinesin heavy chain