anti-Keratin 8 (KRT8) 抗体

KRT8 is a member of the type II keratin family clustered on the long arm of chromosome 12. 再加上,我们可以发Keratin 8 蛋白 (40)Keratin 8 试剂盒 (19)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
KRT8 3856 P05787
KRT8 16691 P11679
KRT8 25626 Q10758
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antibodies-online.cn销售最多的anti-Keratin 8 抗体

Showing 10 out of 805 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 IHC, WB <b>WB Suggested Anti-KRT8 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>Jurkat cell lysate Immunohistochemistry with Small intestine tissue at an antibody concentration of 5µg/ml using anti-KRT8 antibody (ARP42028_P050) 100 μL Log in to see 2至3个工作日
$289.00
详细
Cow 非结合性 IHC, WB <b>WB Suggested Anti-KRT8 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>HepG2 cell lysate Immunohistochemistry with Small intestine tissue at an antibody concentration of 5µg/ml using anti-KRT8 antibody (ARP42029_P050) 100 μL Log in to see 2至3个工作日
$289.00
详细
Cow 非结合性 IC, IF, IHC, WB Immunofluorescent analysis of Cytokeratin 8 staining in NIH3T3 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of Cytokeratin 8 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 13至14个工作日
$487.50
详细
Hamster 小鼠 非结合性 IHC (fro), IF, IHC (p), WB   50 μg Log in to see 6至8个工作日
$368.50
详细
小鼠 非结合性 FACS, IHC (fro), IF, IHC (p), WB   0.1 mg Log in to see 6至8个工作日
$401.50
详细
非结合性 IF (cc), IF (p), IHC (p), WB Formalin-fixed and rat colon tissue labeled with Anti-CK8 Polyclonal Antibody, Unconjugated (ABIN737751) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and mouse stomach tissue labeled with Anti-CK8 Polyclonal Antibody, Unconjugated (ABIN737751) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3至7个工作日
$307.45
详细
小鼠 非结合性 IHC (fro), IF, IHC (p), WB   1 mL Log in to see 6至8个工作日
$308.00
详细
小鼠 非结合性 IHC (fro), IHC (p), WB   1 mL Log in to see 6至8个工作日
$456.50
详细
Cow 小鼠 非结合性 IHC (fro), IF, IHC (p), IP, WB   0.1 mg Log in to see 6至8个工作日
$253.00
详细
非结合性 IF, IHC, ELISA, WB Western blot analysis of extracts from 293 cells, treated with EGF 200ng/ml 30', using Keratin 8 (Ab-431) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using Keratin 8 (Ab-431) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2至3个工作日
$302.50
详细

通过反应活性、应用领域、克隆类型和共轭标记 KRT8 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-Keratin 8 抗体

  1. Human Monoclonal KRT8 Primary Antibody for ICC, FACS - ABIN335327 : Ivanyi, Groeneveld, Van Doornewaard, Mooi, Hageman: Keratin subtypes in carcinomas of the uterine cervix: implications for histogenesis and differential diagnosis. in Cancer research 1990 (PubMed)
    Show all 10 Pubmed References

  2. Human Monoclonal KRT8 Primary Antibody for ICC, FACS - ABIN335211 : Ramaekers, van Niekerk, Poels, Schaafsma, Huijsmans, Robben, Schaart, Vooijs: Use of monoclonal antibodies to keratin 7 in the differential diagnosis of adenocarcinomas. in The American journal of pathology 1990 (PubMed)
    Show all 10 Pubmed References

  3. Human Monoclonal KRT8 Primary Antibody for ICC, IHC (fro) - ABIN920531 : Ljubimov, Bartek, Couchman, Kapuller, Veselov, Kovarik, Perevoshchikov, Krutovskikh: Distribution of individual components of basement membrane in human colon polyps and adenocarcinomas as revealed by monoclonal antibodies. in International journal of cancer. Journal international du cancer 1992 (PubMed)
    Show all 4 Pubmed References

  4. Hamster Monoclonal KRT8 Primary Antibody for IHC (fro), IHC (p) - ABIN920532 : Moll, Franke, Schiller, Geiger, Krepler: The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells. in Cell 1983 (PubMed)
    Show all 4 Pubmed References

  5. Human Monoclonal KRT8 Primary Antibody for ICC, IHC (fro) - ABIN920530 : Troyanovsky, Guelstein, Tchipysheva, Krutovskikh, Bannikov: Patterns of expression of keratin 17 in human epithelia: dependency on cell position. in Journal of cell science 1990 (PubMed)
    Show all 4 Pubmed References

  6. Human Polyclonal KRT8 Primary Antibody for IF (cc), IF (p) - ABIN737751 : Zhang, Li, Fu, Li: Calcitonin is expressed in the submaxillary glands of rats. in Bosnian journal of basic medical sciences / Udruženje basi?nih mediciniskih znanosti = Association of Basic Medical Sciences 2014 (PubMed)
    Show all 3 Pubmed References

  7. Chicken Monoclonal KRT8 Primary Antibody for IHC (fro), IHC (p) - ABIN268153 : Rossdeutscher, Li, Luco, Fadhil, Ochietti, Camirand, Huang, Reinhardt, Muller, Kremer: Chemoprevention activity of 25-hydroxyvitamin D in the MMTV-PyMT mouse model of breast cancer. in Cancer prevention research (Philadelphia, Pa.) 2015 (PubMed)
    Show all 2 Pubmed References

  8. Human Monoclonal KRT8 Primary Antibody for IHC (fro), IHC (p) - ABIN284054 : Fernandez-Valdivia, Mukherjee, Ying, Li, Paquet, DeMayo, Lydon: The RANKL signaling axis is sufficient to elicit ductal side-branching and alveologenesis in the mammary gland of the virgin mouse. in Developmental biology 2009 (PubMed)
    Show all 2 Pubmed References

  9. Human Monoclonal KRT8 Primary Antibody for IHC (fro), IHC (p) - ABIN284055 : Bardag-Gorce, Oliva, Li, French, French: SAMe prevents the induction of the immunoproteasome and preserves the 26S proteasome in the DDC-induced MDB mouse model. in Experimental and molecular pathology 2010 (PubMed)
    Show all 2 Pubmed References

  10. Human Monoclonal KRT8 Primary Antibody for IF, IHC - ABIN965965 : Walker, Harris, Holloway, McKenzie, Wells, Robinson, Morris: Cytokeratin KRT8/18 expression differentiates distinct subtypes of grade 3 invasive ductal carcinoma of the breast. in Cancer genetics and cytogenetics 2007 (PubMed)
    Show all 2 Pubmed References

更多抗Keratin 8的相互作用对抗体

Human Keratin 8 (KRT8) interaction partners

  1. Histopathological differences between Magnetic resonance-guided high-intensity focused ultrasound (MR-HIFU)-ablated tissue and radiofrequency (RF)-ablated tissue were demonstrated. CK-8 was more reliable for cell viability assessment than H&E when used directly after ablation

  2. Loss of activating transcription factor 3 (ATF3 (显示 ATF3 抗体)) in knockout mice promotes the emergence of keratins CK5 (显示 KRT5 抗体)+CK8+ epithelial cells.

  3. Data show that the filament elongation of both desmin (显示 DES 抗体) and keratin K8/K18 (显示 KRT18 抗体) proceeds very similar to that of vimentin (显示 VIM 抗体).

  4. New insights into interactions between the nucleotide-binding domain of CFTR (显示 CFTR 抗体) and keratin 8.

  5. We present results of a multicentre study measuring UBC (显示 RPS27A 抗体)((R)) Rapid Test(test that detects fragments of cytokeratins 8 and 18 in urine) in bladder cancer patients and healthy controls with focus on carcinoma in situ (CIS (显示 CISH 抗体)) and high-grade bladder cancer.

  6. Data show that after siRNA transfection, TGF-beta1 (显示 TGFB1 抗体) protein level was decreased, and CK18 (显示 KRT18 抗体) proteins was decreased, while CK8 proteins was increased, and TERT (显示 TERT 抗体) protein expression was slightly increased at 96 h.

  7. The interplay between Solo protein and keratin 8/keratin 18 filaments plays a crucial role in tensile force-induced RhoA activation and consequent actin cytoskeletal reinforcement in endothelial cells.

  8. K8/18 filaments provide resistance to apoptosis in granulosa cell tumor cells by impairing FAS (显示 FAS 抗体) expression.

  9. These metastatic tumors revealed no detectable expression of CK8/18, E-cadherin (显示 CDH1 抗体), VCAM-1 (显示 VCAM1 抗体), and ICAM-1 (显示 ICAM1 抗体)

  10. Data show that loss of epithelial membrane protein 2 (EMP2) is involved in sphingosylphosphorylcholine (SPC (显示 UCN3 抗体))-induced phosphorylation of keratin 8 (K8) via ubiquitination of protein phosphatase 2 (PP2A (显示 PPP2R4 抗体)) through alpha4 phosphoprotein (显示 IGBP1 抗体) by caveolin-1 (cav-1 (显示 CAV1 抗体)).

Pig (Porcine) Keratin 8 (KRT8) interaction partners

  1. This study reveals clear genetic-statistical evidence for a link of KRT8, FAF1 (显示 FAF1 抗体) and PTH1R (显示 PTH1R 抗体) with some of leg weakness related traits in pigs.

  2. Mechanical injury of vascular smooth muscle up-regulated keratin 8.

Cow (Bovine) Keratin 8 (KRT8) interaction partners

  1. Results did not support that K8/K18 (显示 KRT18 抗体) filaments influence the expression of Fas (显示 FAS 抗体) on the surface of luteal cells.

Mouse (Murine) Keratin 8 (KRT8) interaction partners

  1. Mitochondria in K8 wild-type beta cells and MIN6 insulinoma cells overexpressing K8 and 18 are more stationary compared with mitochondria in keratin-deficient cells

  2. K8/K18 (显示 KRT18 抗体)-dependent PKCdelta (显示 PKCd 抗体)- and ASMase (显示 SMPD1 抗体)-mediated modulation of lipid raft size can explain the more prominent FasR-mediated signaling resulting from K8/K18 (显示 KRT18 抗体) loss.

  3. DRA mRNA levels were decreased by three- to fourfold and DRA protein was almost entirely lost in K8-/- cecum and proximal and distal colon compared with K8+/+.

  4. Upregulation of IL-22 (显示 IL22 抗体) in combination with a complete loss of its negative regulator IL-22BP (显示 IL22RA2 抗体), and increased downstream STAT3 (显示 STAT3 抗体)-signaling in K8(-/-) and K8(-/-)Apc (显示 APC 抗体)(Min/+) colonic epithelia confirmed that the IL-22 (显示 IL22 抗体) pathway, important in inflammation, proliferation and tissue regeneration

  5. Krt8 deletion (Krt8(-/-)) in a mouse model of cystic fibrosis (显示 S100A8 抗体) (F508del-Cftr (显示 CFTR 抗体) mice) increased the levels of circulating markers of bone formation, corrected the expression of osteoblast phenotypic genes, promoted trabecular bone formation and improved bone mass and microarchitecture. Krt8 deletion corrected overactive NF-kappaB (显示 NFKB1 抗体) signaling & decreased Wnt (显示 WNT2 抗体)-beta-catenin (显示 CTNNB1 抗体) signaling induced by F508del-Cftr (显示 CFTR 抗体) mutation in osteoblasts.

  6. Autoantibodies to several antigens were identified in 81% of K8-null male mice 8 mo or older. Similar autoantibodies were detected in aging K18 (显示 KRT18 抗体)-null male mice that had a related liver phenotype but normal colon compared with K8-null mice

  7. The regulation of the SCFA-MCT1 (显示 MCTS1 抗体)-HMGCS2 (显示 HMGCS2 抗体) axis is disrupted in K8(-/-) colonocytes, suggesting a role for keratins in colonocyte energy metabolism and homeostasis.

  8. In several liver stress models epiplakin and K8 genes displayed identical expression patterns and transgenic K8 overexpression resulted in elevated hepatic epiplakin levels.

  9. In human failing myocardium, where TNF-alpha (显示 TNF 抗体) expression is upregulated, K8/K18 (显示 KRT18 抗体) were also ectopically expressed

  10. The findings demonstrate the near complete loss of K8/K18 (显示 KRT18 抗体) with concomitant high levels of vimentin (显示 VIM 抗体) in CT26 (显示 DDX53 抗体) cells, a chemically-induced mouse colonic tumor.

Zebrafish Keratin 8 (KRT8) interaction partners

  1. Data identify Danio rerio keratins 8/18 as the true orthologs of the human keratin pair 8/18.

Keratin 8 (KRT8) 抗原简介

蛋白简介

This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with anti-Keratin 8 (KRT8) 抗体

  • keratin 8 (krt8) 抗体
  • keratin, type II cytoskeletal 8 pseudogene (LOC693415) 抗体
  • keratin, type II cytoskeletal 8 (LOC697116) 抗体
  • keratin 8 (KRT8) 抗体
  • keratin 8 pseudogene (LOC743020) 抗体
  • keratin 8 pseudogene (LOC100345306) 抗体
  • keratin 8 (Krt8) 抗体
  • keratin 8 S homeolog (krt8.S) 抗体
  • AA960620 抗体
  • AL022697 抗体
  • AU019895 抗体
  • Card2 抗体
  • cb186 抗体
  • CK-8 抗体
  • CK8 抗体
  • CYK8 抗体
  • CYKER 抗体
  • DKFZp468F2127 抗体
  • DreK8 抗体
  • EndoA 抗体
  • K2C8 抗体
  • K8 抗体
  • KERATIN8 抗体
  • KO 抗体
  • Krt-2.8 抗体
  • krt2-5 抗体
  • krt2-8 抗体
  • KRT8 抗体
  • MGC69490 抗体
  • sb:cb186 抗体
  • wu:fa20h05 抗体
  • wu:fa95h10 抗体
  • wu:fb96c06 抗体
  • zf-K8 抗体
  • zfk8 抗体

Protein level used designations for anti-Keratin 8 (KRT8) 抗体

keratin 8 , keratin complex 2, basic, gene 5 , cytokeratin 8 , cytokeratin-8 , keratin, type II cytoskeletal 8 , type-II keratin Kb8 , CK-8 , K8 , KERA , cytokeratin-A , keratin-8 , cytokeratin endo A , keratin complex 2, basic, gene 8 , etID33550.23 , etID43142.23 , etID43142.8 , keratin, type 2, gene 8

GENE ID SPECIES
431676 Xenopus (Silurana) tropicalis
693415 Macaca mulatta
697116 Macaca mulatta
700449 Macaca mulatta
737628 Pan troglodytes
743020 Pan troglodytes
100174430 Pongo abelii
100345306 Oryctolagus cuniculus
3856 Homo sapiens
100152077 Sus scrofa
281269 Bos taurus
101110495 Ovis aries
100348891 Oryctolagus cuniculus
16691 Mus musculus
25626 Rattus norvegicus
797433 Danio rerio
380217 Xenopus laevis
426896 Gallus gallus
486513 Canis lupus familiaris
anti-Keratin 8 (KRT8) 抗体 精选生产商
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