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KRT8 is a member of the type II keratin family clustered on the long arm of chromosome 12. 再加上，我们可以发Keratin 8 蛋白 (49) 和 Keratin 8 试剂盒 (17)和数多这个蛋白质的别的产品。
Showing 10 out of 735 products:
Human Monoclonal KRT8 Primary Antibody for FACS, IHC (fro) - ABIN112173
Ivanyi, Groeneveld, Van Doornewaard, Mooi, Hageman: Keratin subtypes in carcinomas of the uterine cervix: implications for histogenesis and differential diagnosis. in Cancer research 1990
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Human Monoclonal KRT8 Primary Antibody for IHC (fro), IF - ABIN1106942
Odin, Obrink: Quantitative determination of the organ distribution of the cell adhesion molecule cell-CAM 105 by radioimmunoassay. in Experimental cell research 1987
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Hamster Monoclonal KRT8 Primary Antibody for IHC (fro), IF - ABIN112171
Bártek, Vojt?sek, Stasková, Bártková, Kerekés, Rejthar, Kovarík: A series of 14 new monoclonal antibodies to keratins: characterization and value in diagnostic histopathology. in The Journal of pathology 1991
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Human Polyclonal KRT8 Primary Antibody for IF, IHC (p) - ABIN197582
Nakamichi, Hatakeyama, Nakayama: Formation of Mallory body-like inclusions and cell death induced by deregulated expression of keratin 18. in Molecular biology of the cell 2002
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Human Monoclonal KRT8 Primary Antibody for FACS, IHC (fro) - ABIN112350
Guelstein, Tchypysheva, Ermilova, Litvinova, Troyanovsky, Bannikov: Monoclonal antibody mapping of keratins 8 and 17 and of vimentin in normal human mammary gland, benign tumors, dysplasias and breast cancer. in International journal of cancer. Journal international du cancer 1988
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Human Monoclonal KRT8 Primary Antibody for IHC (fro), IHC (p) - ABIN114674
Waseem, Karsten, Leigh, Purkis, Waseem, Lane: Conformational changes in the rod domain of human keratin 8 following heterotypic association with keratin 18 and its implication for filament stability. in Biochemistry 2004
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Chicken Polyclonal KRT8 Primary Antibody for IHC, WB - ABIN2777113
Moon, Yau, Wright, Zahradka: Injury-induced expression of cytokeratins 8 and 18 by vascular smooth muscle cells requires concurrent activation of cytoskeletal and growth factor receptors. in Canadian journal of physiology and pharmacology 2008
Human Monoclonal KRT8 Primary Antibody for ICC, IHC - ABIN969080
Walker, Harris, Holloway, McKenzie, Wells, Robinson, Morris: Cytokeratin KRT8/18 expression differentiates distinct subtypes of grade 3 invasive ductal carcinoma of the breast. in Cancer genetics and cytogenetics 2007
Cow (Bovine) Polyclonal KRT8 Primary Antibody for IHC, WB - ABIN2777112
Oh, Yang, Hahn, Kim, Byun, Jeon, Kim, Song, Noh, Kim, Yoo, Kim, Kim: Transcriptome analysis of human gastric cancer. in Mammalian genome : official journal of the International Mammalian Genome Society 2005
We present results of a multicentre study measuring UBC (显示 RPS27A 抗体)((R)) Rapid Test(test that detects fragments of cytokeratins 8 and 18 in urine) in bladder cancer patients and healthy controls with focus on carcinoma in situ (CIS (显示 CISH 抗体)) and high-grade bladder cancer.
Data show that after siRNA transfection, TGF-beta1 (显示 TGFB1 抗体) protein level was decreased, and CK18 (显示 KRT18 抗体) proteins was decreased, while CK8 proteins was increased, and TERT (显示 TERT 抗体) protein expression was slightly increased at 96 h.
The interplay between Solo protein and keratin 8/keratin 18 filaments plays a crucial role in tensile force-induced RhoA activation and consequent actin cytoskeletal reinforcement in endothelial cells.
K8/18 filaments provide resistance to apoptosis in granulosa cell tumor cells by impairing FAS (显示 FAS 抗体) expression.
These metastatic tumors revealed no detectable expression of CK8/18, E-cadherin (显示 CDH1 抗体), VCAM-1 (显示 VCAM1 抗体), and ICAM-1 (显示 ICAM1 抗体)
Data show that loss of epithelial membrane protein 2 (EMP2) is involved in sphingosylphosphorylcholine (SPC (显示 UCN3 抗体))-induced phosphorylation of keratin 8 (K8) via ubiquitination of protein phosphatase 2 (PP2A (显示 PPP2R4 抗体)) through alpha4 phosphoprotein (显示 IGBP1 抗体) by caveolin-1 (cav-1 (显示 CAV1 抗体)).
In human failing myocardium, where TNF-alpha (显示 TNF 抗体) expression is upregulated, K8/K18 (显示 KRT18 抗体) were also ectopically expressed
Human KRT8 variants promote acetaminophen induced hepatotoxicity in mouse models.
Syndecan-1 (显示 SDC1 抗体) is involved in morphogenesis of the developing tooth crown and cervical loops, andntogether with CK8 and vimentin (显示 VIM 抗体) in differentiation of preameloblasts and preodontoblasts.
This is the first time intestinal cells have been suggested also functionally impaired by K8/K18 (显示 KRT18 抗体) mutations.
This study reveals clear genetic-statistical evidence for a link of KRT8, FAF1 (显示 FAF1 抗体) and PTH1R (显示 PTH1R 抗体) with some of leg weakness related traits in pigs.
Mechanical injury of vascular smooth muscle up-regulated keratin 8.
Results did not support that K8/K18 (显示 KRT18 抗体) filaments influence the expression of Fas (显示 FAS 抗体) on the surface of luteal cells.
DRA mRNA levels were decreased by three- to fourfold and DRA protein was almost entirely lost in K8-/- cecum and proximal and distal colon compared with K8+/+.
Upregulation of IL-22 (显示 IL22 抗体) in combination with a complete loss of its negative regulator IL-22BP (显示 IL22RA2 抗体), and increased downstream STAT3 (显示 STAT3 抗体)-signaling in K8(-/-) and K8(-/-)Apc (显示 APC 抗体)(Min/+) colonic epithelia confirmed that the IL-22 (显示 IL22 抗体) pathway, important in inflammation, proliferation and tissue regeneration
Krt8 deletion (Krt8(-/-)) in a mouse model of cystic fibrosis (显示 S100A8 抗体) (F508del-Cftr (显示 CFTR 抗体) mice) increased the levels of circulating markers of bone formation, corrected the expression of osteoblast phenotypic genes, promoted trabecular bone formation and improved bone mass and microarchitecture. Krt8 deletion corrected overactive NF-kappaB (显示 NFKB1 抗体) signaling & decreased Wnt (显示 WNT2 抗体)-beta-catenin (显示 CTNNB1 抗体) signaling induced by F508del-Cftr (显示 CFTR 抗体) mutation in osteoblasts.
Autoantibodies to several antigens were identified in 81% of K8-null male mice 8 mo or older. Similar autoantibodies were detected in aging K18 (显示 KRT18 抗体)-null male mice that had a related liver phenotype but normal colon compared with K8-null mice
The regulation of the SCFA-MCT1 (显示 MCTS1 抗体)-HMGCS2 (显示 HMGCS2 抗体) axis is disrupted in K8(-/-) colonocytes, suggesting a role for keratins in colonocyte energy metabolism and homeostasis.
In several liver stress models epiplakin and K8 genes displayed identical expression patterns and transgenic K8 overexpression resulted in elevated hepatic epiplakin levels.
The findings demonstrate the near complete loss of K8/K18 (显示 KRT18 抗体) with concomitant high levels of vimentin (显示 VIM 抗体) in CT26 (显示 DDX53 抗体) cells, a chemically-induced mouse colonic tumor.
Directed expression of a chimeric type II keratin (显示 KRT80 抗体) partially rescues keratin 5 (显示 KRT36 抗体)-null mice.
Keratin 8 is required for the maintenance of architectural structure in thymus epithelium.
Data identify Danio rerio keratins 8/18 as the true orthologs of the human keratin pair 8/18.
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.
, keratin complex 2, basic, gene 5
, cytokeratin 8
, keratin, type II cytoskeletal 8
, type-II keratin Kb8
, cytokeratin endo A
, keratin complex 2, basic, gene 8
, keratin, type 2, gene 8