anti-Keratin 12 (KRT12) 抗体

KRT12 encodes the type I intermediate filament chain keratin 12, expressed in corneal epithelia. 再加上,我们可以发Keratin 12 蛋白 (8)Keratin 12 试剂盒 (2)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
KRT12 3859 Q99456
KRT12 268482  
KRT12 360625 Q6IFW5

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产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 EIA, IHC (p), WB KRT12 Antibdy (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of KRT12 Antibdy (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. KRT12 Antibody (C-term) western blot analysis in K562 cell line lysates (35µg/lane).This demonstrates the KRT12 antibody detected the KRT12 protein (arrow). 0.4 mL Log in to see 29至35个工作日
¥4,086.26
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豚鼠 非结合性 IHC (fro), IF, IHC (p), WB   0.1 mL Log in to see 29至35个工作日
¥4,187.20
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非结合性 FACS, IHC (p), WB KRT12 Antibdy (C-term) (ABIN656663) immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 5至8个工作日
¥2,325.14
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非结合性 IF (p), IHC (p) Lane 1: rat liver lysates Lane 2: rat brain lysates probed with Anti CK12/Cytokeratin 12 Polyclonal Antibody, Unconjugated (ABIN872955) at 1:200 in 4 °C. Followed by conjugation to secondary antibody  at 1:3000 90min in 37 °C. Predicted band 52kD. Observed band size: 52kD. Formalin-fixed and paraffin embedded mouse stomach labeled with Anti-CK12 Polyclonal Antibody, Unconjugated (ABIN872955) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 5至7个工作日
¥2,610.23
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Alexa Fluor 647 IF (p)   100 μL Log in to see 14至17个工作日
¥3,555.98
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Cy5 IF (p)   100 μL Log in to see 14至17个工作日
¥3,555.98
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Alexa Fluor 488 IF (p)   100 μL Log in to see 14至17个工作日
¥3,555.98
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Cy5.5 IF (p)   100 μL Log in to see 14至17个工作日
¥3,555.98
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Cy7 IF (p)   100 μL Log in to see 14至17个工作日
¥3,555.98
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Alexa Fluor 555 IF (p)   100 μL Log in to see 14至17个工作日
¥3,555.98
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通过反应活性、应用领域、克隆类型和共轭标记 KRT12 抗体

特性 应用范围 宿主 克隆类型 标记
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更多抗Keratin 12的相互作用对抗体

Human Keratin 12 (KRT12) interaction partners

  1. we show that the two PAX6 (显示 PAX6 抗体) isoforms differentially and cooperatively regulate the expression of genes specific to the structure and functions of the corneal epithelium, particularly keratin 3 (KRT3) and keratin 12 (KRT12). PAX6 (显示 PAX6 抗体) isoform-a induced KRT3 expression by targeting its upstream region. KLF4 (显示 KLF4 抗体) enhanced this induction. A combination of PAX6 (显示 PAX6 抗体) isoform-b, KLF4 (显示 KLF4 抗体), and OCT4 (显示 POU5F1 抗体) induced KRT12 expression

  2. Combined with an effective delivery vehicle this siRNA approach represents a viable treatment option for prevention of the MECD pathology observed in K12-Leu132Pro heterozygous individuals.

  3. We identified a novel missense mutation of the KRT12 gene in Meesmann corneal dystrophy. The in vivo confocal microscopy examinations revealed previously unreported depth-dependent ultrastructural changes in the living cornea.

  4. Exon sequencing of KRT3 and KRT12 in six affected and eight unaffected individuals did not detect any mutations or nucleotide sequence variants in Meesmann epithelial corneal dystrophy.

  5. The Leu132Pro missense mutation is within the helix-initiation motif of the keratin and is predicted to result in a significant structural change of the K12 protein.

  6. The lead siRNA, with an IC(50) of thirty picomolar, showed no keratin off-target effects or activation of TLR3 (显示 TLR3 抗体) in the concentration ranges tested.

  7. Novel missense mutation within the highly conserved helix-initiation motif of KRT12 causing Meesmann's corneal dystrophy in a German family.

  8. Heterozygous Ala137Pro mutation in keratin 12 gene found in Japanese with Meesmann's corneal dystrophy.

  9. A novel missense mutation (Y429C) in KRT12 lead to MCD in 2 unrelated Taiwanese families.

  10. Mutation in the KRT12 gene is associated with Meesmann corneal dystrophy

Mouse (Murine) Keratin 12 (KRT12) interaction partners

  1. clonal limbal stem cells randomly activate Krt12 alleles in the process of terminal differentiation in cornea

Keratin 12 (KRT12) 抗原简介

蛋白简介

KRT12 encodes the type I intermediate filament chain keratin 12, expressed in corneal epithelia. Mutations in this gene lead to Meesmann corneal dystrophy.

Gene names and symbols associated with anti-Keratin 12 (KRT12) 抗体

  • zgc:92533 (zgc:92533) 抗体
  • keratin 12 (KRT12) 抗体
  • keratin 12 (krt12) 抗体
  • keratin 12 (Krt12) 抗体
  • keratin K12 (LOC100009289) 抗体
  • AI835216 抗体
  • fb05e09 抗体
  • K12 抗体
  • Ka12 抗体
  • Krt-12 抗体
  • Krt1-12 抗体
  • wu:fa91b04 抗体
  • wu:fa97a07 抗体
  • wu:fb05e09 抗体
  • xk81b2 抗体

Protein level used designations for anti-Keratin 12 (KRT12) 抗体

keratin 12 , fa97a07 , krtt1c19a , cytokeratin , type I keratin , keratin 12 (Meesmann corneal dystrophy) , CK-12 , cytokeratin-12 , keratin, type I cytoskeletal 12 , keratin-12 , Keratin, type I cytoskeletal 12 (Cytokeratin 12) , keratin complex 1, acidic, gene 12 , K12 , keratin K12 , type I keratin KA12 , keratin, type I cytoskeletal 47 kDa , B2 keratin

GENE ID SPECIES
445051 Danio rerio
100034663 Canis lupus familiaris
100144436 Xenopus (Silurana) tropicalis
468241 Pan troglodytes
3859 Homo sapiens
268482 Mus musculus
360625 Rattus norvegicus
398464 Xenopus laevis
100009289 Oryctolagus cuniculus
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