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Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. 再加上，我们可以发Junctophilin 1 抗体 (25) 和 Junctophilin 1 蛋白 (6)和数多这个蛋白质的别的产品。
Results show that JPH1 and GDAP1 (显示 GDAP1 ELISA试剂盒) share a common pathway and depend on each other; therefore, JPH1 can contribute to the phenotypical consequences of GDAP1 (显示 GDAP1 ELISA试剂盒) mutations.
This study suggests that genetic variants of JPH1 may modulate the effect of smoking on carotid plaque burden.
This study demonstrates that both JP1 and JP2 (显示 JPH2 ELISA试剂盒) in skeletal muscle undergo Ca2 (显示 CA2 ELISA试剂盒)+-dependent proteolysis by endogenous proteases when the intracellular Ca2 (显示 CA2 ELISA试剂盒)+ is raised within the physiological range for a sustained period
JP1 and JP2 (显示 JPH2 ELISA试剂盒) can facilitate the assembly of DHPR (显示 QDPR ELISA试剂盒) with other proteins of the excitation-contraction coupling machinery
JP1 gene is expressed during the whole process of cardiogenesis, while JP1 protein only appears during the early stage.
an important fraction of resting plasmalemmal Ca(2 (显示 CA2 ELISA试剂盒)+) permeability is mediated by the Orai1 (显示 TMEM132A ELISA试剂盒) pathway, which contributes to the control of [Ca(2 (显示 CA2 ELISA试剂盒)+)](rest) and resting Ca(2 (显示 CA2 ELISA试剂盒)+) stores and that this pathway is defective in JP1 KO myotubes
Skeletal muscle JP1/2 damage is significantly associated with early (0-3 days) strength deficits after performance of eccentric contractions.
Abnormal junctional membrane structures in cardiac myocytes in transgenic mice expressing junctophilin type 1.
We report a novel Junctophilin subtype, JP-4 (显示 JPH4 ELISA试剂盒), encoded in the human (chromosome 14q11.1) and mouse (chromosome 14C1-2) genomes. JP-4 (显示 JPH4 ELISA试剂盒) shares characteristic structural features with other JP subtypes, and is found in the brain.
Junctophilins support the Ca(2 (显示 CA2 ELISA试剂盒)+)-mediated communication between voltage-gated Ca(2 (显示 CA2 ELISA试剂盒)+) channels, which modulates the excitability of Purkinje cells and is fundamental to cerebellar long-term depression and motor functions.
Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. This gene is a member of the junctophilin gene family.
, junctophilin 1a
, junctophilin type 1
, junctophilin type1