Junctional Adhesion Molecule 3 (JAM3) ELISA试剂盒

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. 再加上,我们可以发JAM3 抗体 (103)JAM3 蛋白 (13)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
JAM3 83964 Q9D8B7
JAM3 83700 Q9BX67
JAM3 315509 Q68FQ2
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产品编号 适用 灵敏度 范围 图像 规格 供应商 交付 价格 详细
6.2 pg/mL 15.625-1000 pg/mL 96 Tests Log in to see 15至17个工作日
$983.85
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大鼠 1.56 pg/mL 6.25-400 pg/mL Typical standard curve 96 Tests Log in to see 15至18个工作日
$910.56
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小鼠 1.95 pg/mL 7.8-500 pg/mL Typical standard curve 96 Tests Log in to see 15至18个工作日
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6.5 pg/mL 15.62 pg/mL - 1000 pg/mL   96 Tests Log in to see 8至12个工作日
$840.25
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适于 JAM3 相互作用对的更多 ELISA 试剂盒

Zebrafish Junctional Adhesion Molecule 3 (JAM3) interaction partners

  1. interaction between Jamb (显示 JAM2 ELISA试剂盒) and Jamc expressed by neighbouring cells is essential for fusion. jamc is ectopically expressed in prdm1a (显示 PRDM1 ELISA试剂盒) mutant slow muscle precursors, which inappropriately fuse with other myocytes.

Mouse (Murine) Junctional Adhesion Molecule 3 (JAM3) interaction partners

  1. JAM-B (显示 JAM2 ELISA试剂盒)/JAM-C mediated interaction between endothelial cells and stellate cells stabilizes vessel walls and may control the sinusoidal diameter.

  2. Study provides evidence that JAM-C downregulation may contribute to acute pancreatitis-associated lung injury via reverse transendothelial migration of neutrophils.

  3. Endothelial-specific deletion of JAM-C promoted endothelial cell sprouting, and consequently vessel normalisation and revascularisation of the hypoxic retina without altering pathologic neovascularisation.

  4. JAM-C blockade can finely-tune the innate cell migration and accelerate the consequent immune response to L. major without changing the type of the T helper cell response.

  5. Function of Jam-B (显示 JAM2 ELISA试剂盒)/Jam-C interaction in homing and mobilization of human and mouse hematopoietic stem and progenitor cells.

  6. These findings provide evidence for a role for endothelial cell JAM-C in tumor growth and aggressiveness as well as recruitment of pericytes to newly formed blood vessels in a model of ovarian cancer.

  7. JAM-C might be involved in the final steps of trafficking and transmigration of antigen-specific autoaggressive T-cells to the islets of Langerhans.

  8. study suggests that JAM-C(-/-) C57BL/6 mice model the important role for JAM-C in brain development and CSF (显示 CSF2 ELISA试剂盒) homeostasis as recently observed in humans with a loss-of-function mutation in JAM-C

  9. Data show that junctional adhesion molecule-B (JAM-B (显示 JAM2 ELISA试剂盒)) expressed by endothelial cells contributes to murine B16 melanoma cells metastasis through its interaction with junctional adhesion molecule-C (JAM-C) on tumor cells.

  10. Results indicate that in vivo JAM-C shows enrichment at the apical surface and therefore is asymmetrically distributed during cell divisions.

Human Junctional Adhesion Molecule 3 (JAM3) interaction partners

  1. The role of JAM-C in the engraftment of human lymphoma B cells in mice was investigated. The binding of anti-JAM-C antibodies inhibited the phosphorylation of ERK1/2 (显示 MAPK1/3 ELISA试剂盒), without affecting other signaling pathways, identifying for the first time the intracellular MAPK (显示 MAPK1 ELISA试剂盒) cascade as the JAM-C-driven signaling pathway in JAM-C(+) B cells.

  2. blocking JAM-C can reduce the number of atherogenic monocytes/macrophages in plaques by emigration.

  3. Palmitoylation of JAM-C promotes its localization to tight junctions and inhibits transwell migration of A549 lung cancer cells.

  4. Study provides evidence that JAM-C downregulation may contribute to acute pancreatitis-associated lung injury via reverse transendothelial migration of neutrophils.

  5. Suggest JAM3-M4 methylation as a biomarker for diagnosis of preneoplastic and neoplastic lesions of the cervix.

  6. JAM-C inactivation in endothelial cells resulted in increased spreading on fibronectin and enhanced sprouting in vitro in a manner dependent on beta1-integrin and on the activation of the small GTPase RAP1.

  7. Function of Jam-B (显示 JAM2 ELISA试剂盒)/Jam-C interaction in homing and mobilization of human and mouse hematopoietic stem and progenitor cells.

  8. indicate that JAM-C may be a therapeutic target for preventing and treating lymphatic metastases

  9. These findings provide evidence for a role for endothelial cell JAM-C in tumor growth and aggressiveness as well as recruitment of pericytes to newly formed blood vessels in a model of ovarian cancer.

  10. Our study confirms the importance of JAM3 as a component of the junctional complexes and its deficiency leading to a distinctive and catastrophic neonatal presentation of cataracts and hemorrhagic destruction of the brain.

JAM3 抗原简介

Antigen Summary

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family. A mutation in an intron of this gene is associated with hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with JAM3

  • junctional adhesion molecule 3 (JAM3) 抗体
  • junctional adhesion molecule 3b (jam3b) 抗体
  • junctional adhesion molecule 3a (jam3a) 抗体
  • junction adhesion molecule 3 (Jam3) 抗体
  • junctional adhesion molecule 3 (Jam3) 抗体
  • 1110002N23Rik 抗体
  • JAM-2 抗体
  • JAM-3 抗体
  • JAM-C 抗体
  • jam3 抗体
  • JAMC 抗体
  • jamc.2 抗体
  • Jcam3 抗体
  • sr:nyz155 抗体
  • wu:fb30h11 抗体
  • wu:fc08c06 抗体
  • wu:fc13e04 抗体
  • wu:fc25g11 抗体

Protein level used designations for JAM3

junctional adhesion molecule 3 , jamc , jamc.1 , si:ch211-277g22.3 , JAM-C-like protein , junction cell adhesion molecule 3 , junction cell adhesion molecule C , junctional adhesion molecule C , JAM-3 , JAM-C

GENE ID SPECIES
419736 Gallus gallus
451678 Pan troglodytes
569217 Danio rerio
797651 Danio rerio
83964 Mus musculus
83700 Homo sapiens
489271 Canis lupus familiaris
513412 Bos taurus
315509 Rattus norvegicus
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