Jun D Proto-Oncogene 蛋白 (JUND)

The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. 再加上,我们可以发Jun D Proto-Oncogene 抗体 (160)Jun D Proto-Oncogene 试剂盒 (9)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
JUND 3727 P17535
JUND 24518 P52909
JUND 16478 P15066

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产品编号 Origin 资源 标记 图像 规格 供应商 交付 价格 详细
Insect Cells 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 68至72个工作日
¥136,777.64
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Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 68至72个工作日
¥136,777.64
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HOST_HEK-293 Cells Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 28至34个工作日
¥6,414.92
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小麦胚 GST tag 2 μg Log in to see 29至34个工作日
¥2,017.10
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酵母菌 小鸡 His tag   1 mg Log in to see 24至35个工作日
¥10,962.90
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酵母菌 大鼠 His tag   1 mg Log in to see 24至35个工作日
¥11,138.40
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酵母菌 Cow His tag   1 mg Log in to see 24至35个工作日
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大肠杆菌(E. Coli) Fruit Fly 非结合性   5 applications Log in to see 23至28个工作日
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JUND 蛋白 by Origin and Source

Origin 在表达 标记
Human , ,
, ,
Rat (Rattus)

Mouse (Murine)

更多Jun D Proto-Oncogene (JUND)互动伙伴

Xenopus laevis Jun D Proto-Oncogene (JUND) interaction partners

  1. identify AP-1(JunD/c-Fos) as a novel hematopoietic transcription factor and the requirement of AP-1(JunD/c-Fos) in BMP-4 (显示 BMP4 蛋白)-induced hematopoiesis during Xenopus hematopoiesis.

Human Jun D Proto-Oncogene (JUND) interaction partners

  1. MiR (显示 MLXIP 蛋白)-663a suppresses proliferation and invasion by targeting AP-1 (显示 FOSB 蛋白) component JunD in non-small cell lung cancer cells.

  2. studies showed that down-regulation of JunD in response to TGF-beta (显示 TGFB1 蛋白) treatment is mediated via the proteasomal degradation pathway.

  3. CARMA1 (显示 CARD11 蛋白)- and MyD88 (显示 MYD88 蛋白)-dependent activation of Jun (显示 JUN 蛋白)/ATF-type AP-1 (显示 FOSB 蛋白) complexes is a hallmark of ABC (显示 ABCB6 蛋白) diffuse large B-cell lymphomas.

  4. recombinant SERPINE2 (显示 SERPINE2 蛋白) induced a clear inhibition of MMP-13 (显示 MMP13 蛋白) expression in IL-1alpha-stimulated chondrocytes. This inhibitory effect is likely regulated through a pathway involving ERK 1 (显示 MAPK3 蛋白)/2, NF-kappaB (显示 NFKB1 蛋白) and AP-1 (显示 FOSB 蛋白)

  5. miR (显示 MLXIP 蛋白)-494 is a novel regulator of HNPC apoptosis induced by TNF-alpha (显示 TNF 蛋白)

  6. JunD activates miR (显示 MLXIP 蛋白)-29b by enhancing its transcription and processing, which contribute to the inhibitory effect of JunD

  7. Binding of specific AP-1 (显示 FOSB 蛋白) factors, we found JunD associated with the LILRB1 (显示 LILRB1 蛋白) distal promoter.

  8. Cells in contact with basement membrane undergo transient oscillations between two molecular states defined by their TGFBR3 (显示 TGFBR3 蛋白)- JUND expression.

  9. BAG3 (显示 BAG3 蛋白) stabilized JunD mRNA.

  10. Jun (显示 JUN 蛋白) proteins (pc-Jun (显示 JUN 蛋白) and JunD) influence carcinogenesis and tumour progression, suggesting a significant role as prognostic predictors in human ovarian carcinoma.

Cow (Bovine) Jun D Proto-Oncogene (JUND) interaction partners

  1. The present data indicate that bovine dialyzable leukocyte extract can block the AP-1 (显示 JUN 蛋白) DNA-binding activity and expression of several transcriptions factors in breast cancer cells.

Mouse (Murine) Jun D Proto-Oncogene (JUND) interaction partners

  1. Differentiation-mediated activation of JunD results in enhanced TUBB4a expression in P19 embryonal carcinoma cells.

  2. JunD provides protection in aging-induced endothelial dysfunction and may represent a novel target to prevent reactive oxygen species-driven vascular aging.

  3. AP-1 (显示 JUN 蛋白) composed with JunD and Fra2 (显示 FOSL2 蛋白) protein plays a primary role in enhancing the transcription level of the CD11c (显示 ITGAX 蛋白) gene in dendritic cells

  4. Nfe2 (显示 NFE2 蛋白) modulates JunD binding to the Gcm1 (显示 GCM1 蛋白) promoter via acetylation

  5. 5-HT2B (显示 HTR2B 蛋白) blockade enhances liver regeneration by inhibiting induction of TGF-beta1 (显示 TGFB1 蛋白) expression by hepatic stellate cells that is dependent on 5-HT (显示 DDC 蛋白), ERK (显示 EPHB2 蛋白) and JunD.

  6. CDK4 (显示 CDK4 蛋白)-mediated regulation of cell functions via c-Jun (显示 JUN 蛋白) phosphorylation and AP-1 (显示 JUN 蛋白) activation

  7. Downregulation of JunD and cyclin D1 (显示 CCND1 蛋白) expression in myofibroblasts may be important regarding the mechanism of action of MTA (显示 DNMT1 蛋白) in Mdr2 (显示 ABCB4 蛋白)-/- mice

  8. c-Jun (显示 JUN 蛋白), JunB (显示 JUNB 蛋白), and JunD are not functionally equivalent and have both overlapping and independent functions in controlling cellular proliferation, cell-cycle arrest/senescence and the response to stress.

  9. Study supports potential roles for jun (显示 JUN 蛋白) D, jun (显示 JUN 蛋白) B, and fra-1 (显示 FOSL1 蛋白) in the dietary energy restriction regulation of AP-1 (显示 JUN 蛋白) function in the Sencar mouse skin carcinogenesis model.

  10. protects cells from p53 (显示 TP53 蛋白)-dependent senescence and apoptosis

蛋白简介Jun D Proto-Oncogene (JUND)

蛋白简介

The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. It has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternate translation initiation site usage, including non-AUG codons, results in the production of different isoforms.

Gene names and symbols associated with Jun D Proto-Oncogene 蛋白 (JUND)

  • jun D proto-oncogene (jund)
  • jun D proto-oncogene (JUND)
  • jun D proto-oncogene (Jund)
  • Jun proto-oncogene related gene d (Jund)
  • AP-1 蛋白
  • Jund1 蛋白
  • si:dkey-251j8.3 蛋白

Protein level used designations for Jun D Proto-Oncogene 蛋白 (JUND)

transcription factor jun-D , JunD-FL isoform , activator protein 1 , Jun proto-oncogene related gene d1

GENE ID SPECIES
564873 Danio rerio
447259 Xenopus laevis
3727 Homo sapiens
609409 Canis lupus familiaris
517192 Bos taurus
24518 Rattus norvegicus
16478 Mus musculus
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