anti-Interleukin 27 (IL27) 抗体

The protein encoded by IL27 is one of the subunits of a heterodimeric cytokine complex. 再加上,我们可以发IL27 试剂盒 (50)IL27 蛋白 (28)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
IL27 53342 Q8TAD2
IL27 246779 Q8K3I6
IL27 365368  

antibodies-online.cn销售最多的anti-IL27 抗体

Showing 10 out of 180 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
小鼠 大鼠 非结合性 WB 25 μL Log in to see 23至28个工作日
¥3,357.01
详细
非结合性 WB WB Suggested Anti-IL27 AntibodyTitration: 1.0 µg/mL  Positive Control: Fetal Lung 100 μL Log in to see 24至29个工作日
¥3,074.65
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小鼠 非结合性 FACS Detection of IL-27 in PHA + IL-2-treated Human PBMC by Flow Cytometry. Human PBMC, treated with 5 ug/mL PHA and 5 ng/mL rhIL-2 (dark orange filled histogram), or untreated (open histogram, yellow line) were stained with Mouse Anti-Human IL-27 Monoclonal Antibody. To facilitate intracellular staining, cells were fixed with paraformaldehyde and permeabilized with saponin. Detection of IL-27 in PHA + IL-2-treated Human PBMC by Flow Cytometry. Human PBMC, treated with 5 ug/mL PHA and 5 ng/mL rhIL-2 (dark orange filled histogram), or untreated (open histogram, yellow line) were stained with Mouse Anti-Human IL-27 Monoclonal Antibody. To facilitate intracellular staining, cells were fixed with paraformaldehyde and permeabilized with saponin. 100 μg Log in to see 26至31个工作日
¥2,144.03
详细
小鼠 HRP EIA, WB   0.1 mg Log in to see 30至37个工作日
¥3,358.40
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小鼠 PE FACS 1 mL Log in to see 29至35个工作日
¥3,279.08
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小鼠 Biotin WB   100 μg Log in to see 23至28个工作日
¥9,424.48
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非结合性 IHC (p), WB 50 μg Log in to see 29至35个工作日
¥5,095.23
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非结合性 WB 100 μg Log in to see 29至35个工作日
¥5,127.12
详细
小鼠 非结合性 WB IL27 Antibody (Center) (ABIN658144) western blot analysis in mouse liver tissue lysates (35 µg/lane). This demonstrates the IL27 antibody detected the IL27 protein (arrow). 400 μL Log in to see 5至8个工作日
¥2,325.14
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小鼠 FITC FACS 1 mL Log in to see 29至35个工作日
¥3,077.28
详细

通过反应活性、应用领域、克隆类型和共轭标记 IL27 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-IL27 抗体

  1. Mouse (Murine) Polyclonal IL27 Primary Antibody for WB - ABIN1043831 : Pflanz, Timans, Cheung, Rosales, Kanzler, Gilbert, Hibbert, Churakova, Travis, Vaisberg, Blumenschein, Mattson, Wagner, To, Zurawski, McClanahan, Gorman, Bazan, de Waal Malefyt, Rennick, Kastelein: IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells. in Immunity 2002 (PubMed)

  2. Mouse (Murine) Monoclonal IL27 Primary Antibody for WB - ABIN1043836 : Murugaiyan, Mittal, Weiner: Identification of an IL-27/osteopontin axis in dendritic cells and its modulation by IFN-gamma limits IL-17-mediated autoimmune inflammation. in Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)

  3. Human Monoclonal IL27 Primary Antibody for FACS - ABIN4900122 : Seyerl, Kirchberger, Majdic, Seipelt, Jindra, Schrauf, Stöckl: Human rhinoviruses induce IL-35-producing Treg via induction of B7-H1 (CD274) and sialoadhesin (CD169) on DC. in European journal of immunology 2010 (PubMed)

更多抗IL27的相互作用对抗体

Human Interleukin 27 (IL27) interaction partners

  1. HIV and Tat (显示 TAT 抗体) inhibit LPS (显示 IRF6 抗体)-induced IL-27 production in human macrophages via distinct mechanisms: Tat (显示 TAT 抗体) through the inhibition of cIAP-1 (显示 BIRC2 抗体)-TRAF-6 (显示 TRAF6 抗体) and subsequent inhibition of PI3K (显示 PIK3CA 抗体) and p38 (显示 CRK 抗体) MAPKs, whereas HIV through the inhibition of p38 MAPK (显示 MAPK14 抗体) activation.

  2. IL27 (显示 EBI3 抗体) recapitulates IFN-gamma (显示 IFNG 抗体) responses in hepatocellular carcinoma cells, but is inhibited by IL6 (显示 IL6 抗体)-type cytokines.

  3. These findings provide new evidence that IL-27 plays an important role in the proinflammatory capacity of monocytes and macrophages via enhancing IL-1beta (显示 IL1B 抗体) secretion levels triggered by dual LPS (显示 IRF6 抗体)-ATP stimulation.

  4. IL-27 enhanced the cytotoxicity and suppressed the proliferation of ovarian cancer cells

  5. Study of the expression of IL-17 (显示 IL17A 抗体) provides theoretical support for the clinical treatment and prognosis prediction of ovarian epithelial tumor.

  6. the sIL (显示 PMEL 抗体)-6R/p28 (显示 PSMD10 抗体) fusion protein (FP) upregulated IFN-lambda1 expression by increasing the binding abilities of c-Fos and activating transcription factor 1 (显示 AFT1 抗体) to the IFN-lambda1 promoter via the p38 MAPK (显示 MAPK14 抗体) signaling pathway; results demonstrate the important role of sIL (显示 PMEL 抗体)-6R/p28 (显示 PSMD10 抗体) FP in mediating virus-induced type III IFN production.

  7. These results identify IL-27 and its specific receptor IL27RA (显示 IL27RA 抗体) as a critical immune axis for the antiviral immune response and as robust correlates of viral load and proviral reservoir size in mononuclear leukocytes in HIV infection.

  8. serum IL-27 levels were significantly higher in stage III EV71-infected hand, foot, and mouth disease patients with early cardiopulmonary failure and strong correlation with CRP (显示 CRP 抗体) levels; IL27p28 polymorphisms (rs153109, rs17855750, and rs181206) did not influence IL-27 production, and these three SNPs were not associated with EV71 infection risk and clinical stage

  9. these results suggest that IL-27 might predominantly play a protective role in the pathogenesis of psoriasis through abrogating Th17 differentiation.

  10. our data suggest a previously unrecognized role for IL-27 in regulating epithelial cell proliferation and antiviral host defense during the normal wound healing response.

Mouse (Murine) Interleukin 27 (IL27) interaction partners

  1. results identified a novel mechanism of action of IL-27 on Tregs in the context of cancers.

  2. These findings provide new evidence that IL-27 plays an important role in the proinflammatory capacity of monocytes and macrophages via enhancing IL-1beta (显示 IL1B 抗体) secretion levels triggered by dual LPS (显示 TLR4 抗体)-ATP stimulation.

  3. findings show that PGE2 inhibits IL-27 production in macrophages and in splenic conventional dendritic cells; and identify a novel pathway consisting of signaling through EP2/EP4-->induction of cAMP-->downregulation of IFN regulatory factor 1 expression and binding to the p28 IFN-stimulated response element site

  4. these data provide the first evidence that IL-27 signals directly to B (显示 TDO2 抗体) cells promote GCs (显示 UGCG 抗体) and support the role of IL-27 in lupus.

  5. this study shows that IL-27 plays an important role in immune response and pathogen clearance during infection with Candida parapsilosis

  6. Inhibition of IL-27p28 also enhanced the suppressive capacity of adoptively transferred CD4 (显示 CD4 抗体)(+) nTregs by increasing the stability of Foxp3 (显示 FOXP3 抗体) expression.

  7. These data provide evidence of a central role of IL-27 for the control of Th2-mediated allergic diseases.

  8. These data indicate that endogenous IL-27 limits pathology during parainfluenza virus infection

  9. our data suggest a previously unrecognized role for IL-27 in regulating epithelial cell proliferation and antiviral host defense during the normal wound healing response.

  10. recombinant IL-30 showed its biological activity by inhibiting Th17 differentiating from naive CD4 (显示 CD4 抗体)(+) T cells. Therefore, this method of express and purifying IL-30 provides novel procedures to facilitate structural and functions studies of IL-30.

Pig (Porcine) Interleukin 27 (IL27) interaction partners

  1. The open reading frame of IL-27 p28 gene is 720 bp, which encodes a protein of 239 amino acids with a predicted molecular mass of 26.6 kDa. The deduced amino acid sequence of IL-27 p28 showed a high degree of homology to human (63%) and mouse (58%).

IL27 抗原简介

蛋白简介

The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).

Gene names and symbols associated with anti-Interleukin 27 (IL27) 抗体

  • interleukin 27 (IL27) 抗体
  • interleukin 17D (IL17D) 抗体
  • interleukin 27 (Il27) 抗体
  • interleukin 27-like (LOC100349321) 抗体
  • IL-17D 抗体
  • IL-22 抗体
  • IL-27 抗体
  • IL-27A 抗体
  • IL-27p28 抗体
  • IL27 抗体
  • IL27A 抗体
  • IL27p28 抗体
  • Il30 抗体
  • p28 抗体
  • RGD1561420 抗体

Protein level used designations for anti-Interleukin 27 (IL27) 抗体

interleukin 27 , interleukin-17D , interleukin-27 , IL-27 p28 subunit , IL-27 subunit alpha , IL-27-A , IL27-A , interleukin 30 , interleukin-27 subunit alpha , interleukin 27 p28 subunit , p28 , interluekin 27

GENE ID SPECIES
737725 Pan troglodytes
53342 Homo sapiens
246778 Homo sapiens
246779 Mus musculus
365368 Rattus norvegicus
100724612 Cavia porcellus
493187 Sus scrofa
607880 Canis lupus familiaris
614927 Bos taurus
101122495 Ovis aries
101093822 Felis catus
100349321 Oryctolagus cuniculus
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