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The protein encoded by IL1RL1 is a member of the interleukin 1 receptor family. 再加上，我们可以发IL1RL1 抗体 (124) 和 IL1RL1 试剂盒 (29)和数多这个蛋白质的别的产品。
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Heligmosomoides polygyrus Alarmin Release Inhibitor (HpARI) prevents binding of active interleukin-33 (IL-33 (显示 IL33 蛋白)) to the IL-33 (显示 IL33 蛋白) receptor.
this study shows that ST2 (显示 SULT2A1 蛋白) regulates early IL-13 (显示 IL13 蛋白) production in fungus-induced allergic airway inflammation
mice deficient in the receptor for IL-33 (显示 IL33 蛋白) (Il1rl1-/-) demonstrated enhanced lung clearance of Aspergillus fumigatus
This stuidy shown that the mRNA expression of IL-33 and ST2 receptors is increased in the CNS of Rocio virus-infected WT mice and that ST2(-/-) mice showed increased susceptibility to infection.
Liver Treg cells show a high expression of ST2 (显示 SULT2A1 蛋白), a cellular receptor for tissue alarmin IL-33 (显示 IL33 蛋白), which is strongly upregulated in the liver of infected mice. These results illustrate the importance of IL-33 (显示 IL33 蛋白) in the suppressive function of liver Treg cells during Cytomegaloviruses (CMVs) infection.
these studies establish a basal defect in eosinophilopoiesis in IL-33 (显示 IL33 蛋白)- and ST2 (显示 SULT2A1 蛋白)-deficient mice and a mechanism whereby IL-33 (显示 IL33 蛋白) supports eosinophils by driving both systemic IL-5 (显示 IL5 蛋白) production and the expansion of IL-5Ralpha-expressing precursor cells
These results shed light on endogenous IL-33/ST2 signaling as a potential immune regulatory mechanism that serves to promote beneficial microglial responses and mitigate ischemic brain injury after stroke.
Plasmodium berghei infection triggered a dramatic increase of IL-33 expression by oligodendrocytes, through ST2 pathway.
Data, including data from studies using knockout mice, suggest that signal transduction via IL33 (显示 IL33 蛋白)/ST2L (显示 TMED1 蛋白) (interleukin 33/interleukin-33 (显示 IL33 蛋白) receptor) plays a cardioprotective role in myocardial remodeling under mechanical stress (which leads to left ventricular hypertrophy and heart failure).
IL-33 acts as a potent immune modulator protecting the liver through activation of ST2(+) Treg cells and control of natural killer cells in immune cell-mediated hepatitis.
The Il1RL1 rs950880 AA homozygote is an independent predictor of all-cause mortality in coronary artery disease and peripheral arterial disease patients.
In a cohort of hypertensive heart failure subjects, soluble ST2 correlates significantly with indicators of right ventricular function.
Data provide evidence that increased IL-33/ST2 levels in patients with chronic kidney disease are an indicator of increased inflammation, impaired endothelial functions, and cardiovascular events.
Serum levels of IL33R were positively correlated with cognitive performance in patients with schizophrenia.
Interleukin 1 receptor-like 1 (ST2/IL1RL1) is a biomarker for cardiac stress and heart failure, which can be associated with cocaine use. Data suggest that serum ST2/IL1RL1 levels are up-regulated by cocaine use; cocaine use appears to be associated with subclinical cardiac stress and damage outside of acute cardiac events; elevated serum ST2/IL1RL1 levels may serve as biomarkers for cocaine-induced cardiac complications.
Preterm labor was associated with diminished expression of the alpha-chain (显示 FCGRT 蛋白) of IL-33 (显示 IL33 蛋白) receptor on choriodecidual B cells.
Study found that macrophages expressed ST2L with a membrane pattern. The membrane pattern of ST2L was strongly expressed if the macrophages infiltrating the shoulder region of the plaque had an epithelioid aspect suggesting its possible role in the pathogenetic mechanisms of atherosclerotic lesions progression and rupture.
The higher levels of IL-33 and its receptor ST2 in tissue and serum reflect an active inflammatory state and may represent a potential biomarker for disease activity.
The genetic risk score for rs1041973 and rs16924161 demonstrated a higher risk for SPT (显示 AGXT 蛋白) positivity against B. tropicalis, the greater the number of risk alleles for both SNPs. Our findings demonstrate a robust association of genetic variants in IL1RL1 and IL33 (显示 IL33 蛋白) SNPs with allergy markers and asthma.
Increased sST2 (显示 SSTR2 蛋白) and IL-10 (显示 IL10 蛋白) but not IL-33 (显示 IL33 蛋白) may be involved in the pathogenic process of IgAN.
The protein encoded by this gene is a member of the interleukin 1 receptor family. Studies of the similar gene in mouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the function of helper T cells. This gene, interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2) and interleukin 1 receptor-like 2 (IL1RL2) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. Alternative splicing of this gene results in multiple transcript variants.
, interleukin-1 receptor-like 1
, lymphocyte antigen 84
, protein T1
, growth stimulation-expressed
, homolog of mouse growth stimulation-expressed
, interleukin 1 receptor-related protein
, fos-responsive gene 1 protein