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Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. 再加上，我们可以发Integrin beta 4 试剂盒 (24) 和 Integrin beta 4 蛋白 (9)和数多这个蛋白质的别的产品。
Showing 10 out of 367 products:
Human Monoclonal Integrin beta 4 Primary Antibody for IF, WB - ABIN968433
Mainiero, Pepe, Wary, Spinardi, Mohammadi, Schlessinger, Giancotti: Signal transduction by the alpha 6 beta 4 integrin: distinct beta 4 subunit sites mediate recruitment of Shc/Grb2 and association with the cytoskeleton of hemidesmosomes. in The EMBO journal 1995
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Mouse (Murine) Monoclonal Integrin beta 4 Primary Antibody for FACS - ABIN120280
Kennel, Foote, Falcioni, Sonnenberg, Stringer, Crouse, Hemler: Analysis of the tumor-associated antigen TSP-180. Identity with alpha 6-beta 4 in the integrin superfamily. in The Journal of biological chemistry 1989
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Mouse (Murine) Monoclonal Integrin beta 4 Primary Antibody for FACS, IHC (fro) - ABIN120281
Kennel, Godfrey, Chang, Lankford, Foote, Makkinje: The beta 4 subunit of the integrin family is displayed on a restricted subset of endothelium in mice. in Journal of cell science 1992
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Human Monoclonal Integrin beta 4 Primary Antibody for FACS, IHC - ABIN1724805
Liu, Qin, Liu, Xiang: Downregulation of integrin β4 decreases the ability of airway epithelial cells to present antigens. in PLoS ONE 2012
Human Monoclonal Integrin beta 4 Primary Antibody for FACS - ABIN319861
Kennel, Epler, Lankford, Foote, Dickas, Canamucio, Cavalierie, Cosimelli, Venturo, Falcioni: Second generation monoclonal antibodies to the human integrin alpha 6 beta 4. in Hybridoma 1990
Mouse (Murine) Monoclonal Integrin beta 4 Primary Antibody for FACS, IHC (fro) - ABIN260163
Lämmermann, Bader, Monkley, Worbs, Wedlich-Söldner, Hirsch, Keller, Förster, Critchley, Fässler, Sixt: Rapid leukocyte migration by integrin-independent flowing and squeezing. in Nature 2008
Human Monoclonal Integrin beta 4 Primary Antibody for FACS, ICC - ABIN4900094
Mierke, Frey, Fellner, Herrmann, Fabry: Integrin α5β1 facilitates cancer cell invasion through enhanced contractile forces. in Journal of cell science 2011
Ferret Monoclonal Integrin beta 4 Primary Antibody for ICC, FACS - ABIN260162
Tra, van Neck, Hovius, van Osch, Perez-Amodio: Characterization of a three-dimensional mucosal equivalent: similarities and differences with native oral mucosa. in Cells, tissues, organs 2012
Expression of the beta 4 subunit of the alpha 6 beta 4 integrin induces monocytic differentiation of 32D/v-Abl (显示 ABL1 抗体) transformed cells. alpha 6 beta 4 integrin promotes growth arrest and differentiation by modulating Abl (显示 ABL1 抗体) kinases and p73 (显示 ARHGAP24 抗体) protein pathway(s).
Integrin beta4 contributes to mammary gland development by sustaining PTHrP (显示 PTHLH 抗体) expression and enabling PTHrP (显示 PTHLH 抗体) signaling.
keratins have a role in controlling beta4-integrin endocytosis involving a plectin (显示 PLEC 抗体)-Erk1/2 (显示 MAPK1/3 抗体)-dependent mechanism relevant for epidermal differentiation and pathogenesis
Up-regulation of integrin beta4 and TRPV1 (显示 TRPV1 抗体) in migrating keratinocytes.
Ectopic induction of Nur77 (显示 NR4A1 抗体) in endothelial cells is sufficient to improve skin wound healing. Furthermore, TR3/Nur77 (显示 NR4A1 抗体) regulates the expression of integrin beta4 by targeting its promoter activity.
Col17a1 (显示 COL17A1 抗体)/ keratinocytes exhibited increased spreading on laminin 332 and accelerated, but less directed cell motility. These effects were accompanied by increased expression of the integrin subunits beta4 and beta1.
Both annexin A7 (显示 ANXA7 抗体) and integrin beta4 were essential for small molecule, 6-amino-2, 3-dihydro-3-hydroxymethyl-1, 4-benzoxazine-induced autophagy.
Findings indicate a function for Id2 in regulating Snai1 (显示 SNAI1 抗体)-mediated repression of integrin beta4.
Targeted deletion of the signaling domain of beta4 inhibited prostate tumor growth and progression in response to loss of p53 (显示 TP53 抗体) and Rb function in a model of prostate cancer (PB-TAg mice).
Deficiency of integrin alpha(6 (显示 ITGA6 抗体))beta(4) is modestly but significantly suppressed reporter-gene transduction by papillomaviruses in conditional integrin beta(4) knockout mice.
For the in vivo experiment, miR (显示 MLXIP 抗体)-182-5p overexpression also promoted the growth and progression of prostate cancer tumors. In this regard, we suggest that miR (显示 MLXIP 抗体)-182-5p may be a key androgen receptor (显示 AR 抗体)-regulated factor that contributes to the development and metastasis of Chinese prostate cancers and may be a potential target for the early diagnosis and therapeutic studies of prostate cancer.
data indicate that the beta4 integrin/FAK (显示 PTK2 抗体) complex and subsequent FAK (显示 PTK2 抗体) activation are essential regulators during the tumorigenicity of colon cancer
This work investigates alpha6beta4 integrin genetic variations (A380T and R1281W) and breast cancer risk in an Argentinian population. No subjects carrying the R1281W mutation in the ITGB4 gene were found and this absence could reflect its high deleterious impact on proteins, so it would be eliminated from the population by natural selection.
analysis of deletions in ITGB4 gene causing epidermolysis bullosa with pyloric atresia [case series]
ITGB4 is overexpressed in hepatocellular carcinoma tissues and promotes metastases of HCC (显示 FAM126A 抗体) by conferring anchorage independence through EGFR (显示 EGFR 抗体)-dependent FAK (显示 PTK2 抗体)-AKT (显示 AKT1 抗体) activation.
High vimentin and low beta4 integrin protein levels are associated with poor survival in oral squamous carcinoma patients.
Endothelial cell overexpression of mutant ITGB4 with specific tyrosines mutated to phenylalanine (Y1440, Y1526 Y1640, or Y1422) resulted in significantly attenuated CS-induced cytokine expression.
This study describes a pro-metastatic EGFR (显示 EGFR 抗体)/Src (显示 SRC 抗体)-dependent beta4 integrin/FAK (显示 PTK2 抗体) complex that is involved in breast cancer malignancy and is a novel therapeutic target for triple-negative breast cancer.
These data suggest that the p53 (显示 TP53 抗体)(R248) mutant endows ovarian cancer cells with increased adhesiveness and that integrin beta4 and Akt (显示 AKT1 抗体) signalling are associated with the mutation-enhanced ovarian cancer-mesothelial cell adhesion.
Changes in beta-integrins gene expression in human prostate cancer cells following ITGB4 knockdown.
Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
integrin beta 4
, integrin beta-4
, CD104 antigen
, integrin beta-4 subunit