Indoleamine 2,3-Dioxygenase 2 (IDO2) ELISA试剂盒

Along with the enzymes encoded by the INDO (MIM 147435) and TDO2 (MIM 191070) genes, the enzyme encoded by the INDOL1 gene metabolizes tryptophan in the kynurenine pathway (Ball et al., 2007 [PubMed 17499941]).[supplied by OMIM, Feb 2011].. 再加上,我们可以发IDO2 抗体 (121)IDO2 蛋白 (8)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
IDO2 169355 Q6ZQW0
大鼠 IDO2 IDO2 681319  
IDO2 209176  

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3.12 pg/mL 12.5-800 pg/mL Typical standard curve 96 Tests Log in to see 9至12个工作日
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小鼠 12.9 pg/mL 31.25-2000 pg/mL 96 Tests Log in to see 7至10个工作日
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Human Indoleamine 2,3-Dioxygenase 2 (IDO2) interaction partners

  1. High IDO2 expression is associated with Colorectal Cancer.

  2. High IDO2 expression is associated with cervical cancer.

  3. functional importance of IDO (显示 IDO1 ELISA试剂盒) enzymes in human Crohn's disease

  4. Human indoleamine 2,3-dioxygenase-2 has substrate specificity and inhibition characteristics distinct from those of indoleamine 2,3-dioxygenase-1 (显示 IDO1 ELISA试剂盒)

  5. These results demonstrate that IDO2 plays a novel role as a negative regulator of IDO1 (显示 IDO1 ELISA试剂盒) by competing for heme-binding with IDO1 (显示 IDO1 ELISA试剂盒).

  6. The IDO2 is now known to catalyze the first and rate-limiting step in the catabolism of tryptophan along a relative newcomer to the kynurenine pathway field.

  7. Multiple-scattering (MS) analysis of EXAFS data on met-indoleamine 2,3-dioxygenase-2 (IDO2) and analysis of XANES have provided the first direct structural information about the axial donor ligands of the iron center for this recently discovered protein.

  8. IDO2 is expressed in both mDCs and plasmacytoid DCs and is not modulated by PGE2. IDO2 expression is constitutively, stably expressed in steady-state conditions and may contribute to the homeostatic tolerogenic capacity of DCs.

  9. Indoleamine2,3-dioxygenase and tryptophanyl-tRNA synthetase (显示 WARS ELISA试剂盒) may play critical roles in the immune pathogenesis of chronic kidney disease.

  10. Purification and kinetic characterization of human indoleamine 2,3-dioxygenases 1 and 2 (IDO1 (显示 IDO1 ELISA试剂盒) and IDO2) and discovery of selective IDO1 (显示 IDO1 ELISA试剂盒) inhibitors.

Mouse (Murine) Indoleamine 2,3-Dioxygenase 2 (IDO2) interaction partners

  1. The IDO2-deficient B cells lacked the ability to upregulate the costimulatory marker CD40 (显示 CD40 ELISA试剂盒), suggesting IDO2 acts at the T-B cell interface to modulate the potency of T cell help needed to promote autoantibody production.

  2. Targeting IDO2 with a monoclonal antibody inhibits autoreactive B and T cell activation and alleviates joint inflammation in two well-characterized preclinical models of arthritis.

  3. Indoleamine-2,3-dioxygenase (IDO (显示 IDO1 ELISA试剂盒)) production by Plasmacytoid dendritic cells (pDCs)is necessary to confer suppressive function to T-Cells, Regulatory (Tregs) in experimental autoimmune encephalomyelitis (EAE).

  4. Ido2 may be important for mouse embryo implantation and decidualization.

  5. The data showed that there is not significant effect of IDO1 (显示 IDO1 ELISA试剂盒) or TDO2 (显示 TDO2 ELISA试剂盒) on mortality in pneumococcal meningitis.

  6. IDO2 is critical for IDO1 (显示 IDO1 ELISA试剂盒)-mediated T-cell regulation and exerts a non-redundant function in inflammation.

  7. Deletion of Ido1 (显示 IDO1 ELISA试剂盒) and reduced mRNA expression for Ido2 neither affected the concentration of the downstream metabolites of tryptophan nor mRNA expression for downstream genes on the kynurenine pathway in inguinal lymph nodes.

  8. results provide important insights into IDO2 function by defining its pathogenic contributions to autoantibody-mediated autoimmunity.

  9. Immunohistochemical analysis in Ido1 (显示 IDO1 ELISA试剂盒)(-/-) mouse epididymis showed that Ido2 protein was extensively upregulated due to the loss of Ido1 (显示 IDO1 ELISA试剂盒) expression.

  10. IDO-1 (显示 IDO1 ELISA试剂盒) and IDO-2 play biologically important, contradictory roles during intracellular protozoal infection - facilitating (Toxoplasma gondii) or suppressing (Leishmania major) microbial clearance in a pathogen-specific manner.

IDO2 抗原简介

Antigen Summary

Along with the enzymes encoded by the INDO (MIM 147435) and TDO2 (MIM 191070) genes, the enzyme encoded by the INDOL1 gene metabolizes tryptophan in the kynurenine pathway (Ball et al., 2007

Gene names and symbols associated with IDO2

  • indoleamine 2,3-dioxygenase 2 (IDO2) 抗体
  • indoleamine 2,3-dioxygenase 2 (Ido2) 抗体
  • AI265623 抗体
  • C230043N17Rik 抗体
  • Ido-2 抗体
  • Indol1 抗体

Protein level used designations for IDO2

indoleamine 2,3-dioxygenase 2 , indoleamine 2,3-dioxygenase 2-like , IDO-2 , indoleamine 2,3-dioxygenase-like 1 protein , indoleamine 2,3-dioxygenase-like protein 1 , indoleamine-pyrrole 2,3 dioxygenase-like 1 , indoleamine-pyrrole 2,3-dioxygenase-like protein 1

GENE ID SPECIES
100402049 Callithrix jacchus
707424 Macaca mulatta
100085939 Ornithorhynchus anatinus
100435160 Pongo abelii
100480334 Ailuropoda melanoleuca
100580956 Nomascus leucogenys
169355 Homo sapiens
482846 Canis lupus familiaris
513810 Bos taurus
681319 Rattus norvegicus
209176 Mus musculus
100056686 Equus caballus
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