anti-Indoleamine 2,3-Dioxygenase 2 (IDO2) 抗体

Along with the enzymes encoded by the INDO (MIM 147435) and TDO2 (MIM 191070) genes, the enzyme encoded by the INDOL1 gene metabolizes tryptophan in the kynurenine pathway (Ball et al., 2007 [PubMed 17499941]).[supplied by OMIM, Feb 2011].. 再加上,我们可以发IDO2 蛋白 (8)IDO2 试剂盒 (5)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
IDO2 169355 Q6ZQW0
IDO2 681319  
IDO2 209176  

antibodies-online.cn销售最多的anti-IDO2 抗体

Showing 10 out of 121 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-IDO2 Antibody Titration: 1.0 ug/ml Positive Control: Fetal Brain 100 μL Log in to see 5至7个工作日
¥20,898.73
详细
Cow 非结合性 WB 100 μL Log in to see 5至7个工作日
¥20,898.73
详细
小鼠 小鼠 非结合性 ELISA, WB Western Blot of Mouse Anti-IDO2 antibody. Lane 1: HEK293 no transgene cell extracts. Lane 2: mouse IDO-2 transgene expressed in 293HEK. Lane 3: mouse IDO-1 transgene expressed in 293HEK. Primary antibody: IDO2 monoclonal Antibody. Secondary antibody: IRDye800™ mouse secondary antibody at 1:10,000 for 45 min at RT. Block: 5% BLOTTO overnight at 4°C. Predicted/Observed size: 44.4 kDa, ~60 kDa for IDO 2. Other band(s): IDO2 splice variants and isoforms 25 μL Log in to see 23至28个工作日
¥3,357.01
详细
非结合性 EIA, IHC (p), WB Immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue reacted with IDO2 / INDOL1 Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. Western blot analysis of IDO2 / INDOL1 Antibody (C-term) in K562 cell line lysates (35ug/lane). 0.4 mL Log in to see 29至35个工作日
¥4,086.26
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小鼠 非结合性 IHC, ELISA, WB Immunofluorescence of Anti-IDO2 Antibody. Tissue: human IDO2 expressing HEK293 cells. Fixation: 0.5% PFA. Antigen retrieval: not required. Primary: IDO2 antibody at 1:50-1:1000 for 1 h at RT. Secondary: Peroxidase rabbit secondary antibody at 1:10,000 for 45min at RT. Localization: IDO-2 is located in the cytosol. Staining: IDO-2 as green fluorescent signal with bis-benzimide nuclear counterstain (blue). 100 μg Log in to see 23至28个工作日
¥9,424.48
详细
小鼠 小鼠 非结合性 ELISA, ICC, IF, WB Western Blot: IDO2 Antibody (1HC) [NBP2-21641] - Western Blot of Mouse Anti-IDO2 antibody. Lane 1: HEK293 no transgene cell extracts.Lane 2: mouse IDO-2 transgene expressed in 293HEK.Lane 3: mouse IDO-1 transgene expressed in 293HEK. IDO2 monoclonal Antibody. Secondary antibody: Dye800 mouse secondary antibody at 1:10,000 for 45 min at RT. Block: 5% Blocking Buffer overnight at 4C.Predicted/Observed size: 44.4 kDa, ~60 kDa for IDO 2. Other band: IDO2 splice variants and isoforms. 0.1 mg Log in to see 25至31个工作日
¥4,395.26
详细
Cow 山羊 非结合性 EIA, WB   0.1 mg Log in to see 30至37个工作日
¥3,065.96
详细
非结合性 WB Anti-INDOL1 antibody, Western blotting Lane 1: A549 Cell Lysate Lane 2: Human Placenta Tissue Lysate Lane 3: A431 Cell Lysate 100 μg Log in to see 26至32个工作日
¥2,560.58
详细
山羊 非结合性 ELISA, IHC (fro), WB Western Blot: IDO2 Antibody [NBP1-45209] - (0.5ug/ml) staining of Human Kidney lysate (35ug protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 25至31个工作日
¥3,333.96
详细
小鼠 非结合性 FACS, WB HEK293T cells transfected with either RC223337 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-IDO2 antibody (ABIN2453838), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IDO2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-IDO2. 100 μL Log in to see 24至29个工作日
¥4,767.17
详细

通过反应活性、应用领域、克隆类型和共轭标记 IDO2 抗体

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引用最多的anti-IDO2 抗体

  1. Human Polyclonal IDO2 Primary Antibody for ELISA, IHC (fro) - ABIN4321036 : Zuliani, Saiagh, Knol, Esbelin, Dréno: Fetal fibroblasts and keratinocytes with immunosuppressive properties for allogeneic cell-based wound therapy. in PLoS ONE 2013 (PubMed)
    Show all 2 Pubmed References

  2. Mouse (Murine) Monoclonal IDO2 Primary Antibody for ELISA, ICC - ABIN4321038 : Metz, Duhadaway, Rust, Munn, Muller, Mautino, Prendergast: Zinc protoporphyrin IX stimulates tumor immunity by disrupting the immunosuppressive enzyme indoleamine 2,3-dioxygenase. in Molecular cancer therapeutics 2010 (PubMed)

  3. Mouse (Murine) Monoclonal IDO2 Primary Antibody for ELISA, WB - ABIN1043821 : Wolff, Driever, Erdlenbruch, Kortmann, Rutkowski, Pietsch, Parker, Metz, Gnekow, Kramm: Intensive chemotherapy improves survival in pediatric high-grade glioma after gross total resection: results of the HIT-GBM-C protocol. in Cancer 2010 (PubMed)

更多抗IDO2的相互作用对抗体

Human Indoleamine 2,3-Dioxygenase 2 (IDO2) interaction partners

  1. High IDO2 expression is associated with Colorectal Cancer.

  2. High IDO2 expression is associated with cervical cancer.

  3. functional importance of IDO (显示 IDO1 抗体) enzymes in human Crohn's disease

  4. Human indoleamine 2,3-dioxygenase-2 has substrate specificity and inhibition characteristics distinct from those of indoleamine 2,3-dioxygenase-1 (显示 IDO1 抗体)

  5. These results demonstrate that IDO2 plays a novel role as a negative regulator of IDO1 (显示 IDO1 抗体) by competing for heme-binding with IDO1 (显示 IDO1 抗体).

  6. The IDO2 is now known to catalyze the first and rate-limiting step in the catabolism of tryptophan along a relative newcomer to the kynurenine pathway field.

  7. Multiple-scattering (MS) analysis of EXAFS data on met-indoleamine 2,3-dioxygenase-2 (IDO2) and analysis of XANES have provided the first direct structural information about the axial donor ligands of the iron center for this recently discovered protein.

  8. IDO2 is expressed in both mDCs and plasmacytoid DCs and is not modulated by PGE2. IDO2 expression is constitutively, stably expressed in steady-state conditions and may contribute to the homeostatic tolerogenic capacity of DCs.

  9. Indoleamine2,3-dioxygenase and tryptophanyl-tRNA synthetase (显示 WARS 抗体) may play critical roles in the immune pathogenesis of chronic kidney disease.

  10. Purification and kinetic characterization of human indoleamine 2,3-dioxygenases 1 and 2 (IDO1 (显示 IDO1 抗体) and IDO2) and discovery of selective IDO1 (显示 IDO1 抗体) inhibitors.

Mouse (Murine) Indoleamine 2,3-Dioxygenase 2 (IDO2) interaction partners

  1. The IDO2-deficient B cells lacked the ability to upregulate the costimulatory marker CD40 (显示 CD40 抗体), suggesting IDO2 acts at the T-B cell interface to modulate the potency of T cell help needed to promote autoantibody production.

  2. Targeting IDO2 with a monoclonal antibody inhibits autoreactive B and T cell activation and alleviates joint inflammation in two well-characterized preclinical models of arthritis.

  3. Indoleamine-2,3-dioxygenase (IDO (显示 IDO1 抗体)) production by Plasmacytoid dendritic cells (pDCs)is necessary to confer suppressive function to T-Cells, Regulatory (Tregs) in experimental autoimmune encephalomyelitis (EAE).

  4. Ido2 may be important for mouse embryo implantation and decidualization.

  5. The data showed that there is not significant effect of IDO1 (显示 IDO1 抗体) or TDO2 (显示 TDO2 抗体) on mortality in pneumococcal meningitis.

  6. IDO2 is critical for IDO1 (显示 IDO1 抗体)-mediated T-cell regulation and exerts a non-redundant function in inflammation.

  7. Deletion of Ido1 (显示 IDO1 抗体) and reduced mRNA expression for Ido2 neither affected the concentration of the downstream metabolites of tryptophan nor mRNA expression for downstream genes on the kynurenine pathway in inguinal lymph nodes.

  8. results provide important insights into IDO2 function by defining its pathogenic contributions to autoantibody-mediated autoimmunity.

  9. Immunohistochemical analysis in Ido1 (显示 IDO1 抗体)(-/-) mouse epididymis showed that Ido2 protein was extensively upregulated due to the loss of Ido1 (显示 IDO1 抗体) expression.

  10. IDO-1 (显示 IDO1 抗体) and IDO-2 play biologically important, contradictory roles during intracellular protozoal infection - facilitating (Toxoplasma gondii) or suppressing (Leishmania major) microbial clearance in a pathogen-specific manner.

IDO2 抗原简介

蛋白简介

Along with the enzymes encoded by the INDO (MIM 147435) and TDO2 (MIM 191070) genes, the enzyme encoded by the INDOL1 gene metabolizes tryptophan in the kynurenine pathway (Ball et al., 2007

Gene names and symbols associated with IDO2

  • indoleamine 2,3-dioxygenase 2 (IDO2) 抗体
  • indoleamine 2,3-dioxygenase 2 (Ido2) 抗体
  • AI265623 抗体
  • C230043N17Rik 抗体
  • Ido-2 抗体
  • Indol1 抗体

Protein level used designations for IDO2

indoleamine 2,3-dioxygenase 2 , indoleamine 2,3-dioxygenase 2-like , IDO-2 , indoleamine 2,3-dioxygenase-like 1 protein , indoleamine 2,3-dioxygenase-like protein 1 , indoleamine-pyrrole 2,3 dioxygenase-like 1 , indoleamine-pyrrole 2,3-dioxygenase-like protein 1

GENE ID SPECIES
100402049 Callithrix jacchus
707424 Macaca mulatta
100085939 Ornithorhynchus anatinus
100435160 Pongo abelii
100480334 Ailuropoda melanoleuca
100580956 Nomascus leucogenys
169355 Homo sapiens
482846 Canis lupus familiaris
513810 Bos taurus
681319 Rattus norvegicus
209176 Mus musculus
100056686 Equus caballus
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