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anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) 抗体

IDO1 encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. 再加上,我们可以发Indoleamine 2,3-Dioxygenase 1 试剂盒 (16)Indoleamine 2,3-Dioxygenase 1 蛋白 (14)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
IDO1 3620 P14902
IDO1 15930 P28776
IDO1 66029 Q9ERD9

antibodies-online.cn销售最多的anti-Indoleamine 2,3-Dioxygenase 1 抗体

Showing 10 out of 177 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 EIA, IHC (p), WB 0.4 mL Log in to see 29至35个工作日
¥4,086.26
详细
非结合性 IHC (p), WB Western blot analysis of anti-INDO Antibody (C-term) (ABIN389194) in 293 cell line lysates (35 µg/lane). INDO(arrow) was detected using the purified polyclonal antibody (1:60 dilution). Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with INDO antibody (C-term) (ABIN389194), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 9至13个工作日
¥2,325.14
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小鼠 小鼠 非结合性 FACS, IHC, ELISA, WB Immunofluorescence Microscopy of Mouse anti-IDO1 Antibody. Cells: HEK293 cells. Fixation: 0.5% PFA. Expressing: mouse IDO-1 (left) and mouse IDO-2 (right). Primary antibody: IDO1 (2E2) monoclonal antibody. Antigen retrieval: not required. Secondary antibody: mouse secondary antibody at 1:10,000 for 45 min at RT. Localization: IDO-1 is located in the cytosol. Staining: IDO1 as red fluorescent signal with bis-benzimide nuclear counterstain (blue). 25 μL Log in to see 23至28个工作日
¥3,357.01
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小鼠 小鼠 非结合性 FACS, IP, IHC, ELISA, WB Western Blot of Mouse Anti-IDO1 Antibody. Lane 1: untreated HeLa cells. Lane 2: IFN-r treated HeLa cells. Load: 35 µg per lane. Primary antibody: IDO 1 Antibody at 1:1000 for overnight at 4°C. Secondary antibody: IRDye800™ mouse secondary antibody at 1:10,000 for 45 min at RT. Block: 5% BLOTTO overnight at 4°C. Predicted/Observed size: 41-42 kDa, 41-42 kDa for IDO-1. Other band(s): none. 25 μL Log in to see 23至28个工作日
¥3,357.01
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小鼠 PE FACS Detection of Indoleamine 2,3-dioxygenase/IDO in Human MDSCs by Flow Cytometry. Human myeloid-derived suppressor cells (MDSCs) treated with 10 ng/mL Recombinant Human IL-6. 100 Tests Log in to see 26至31个工作日
¥2,615.71
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小鼠 Alexa Fluor 488 FACS Detection of Indoleamine 2,3-dioxygenase/IDO in Human MDSCs by Flow Cytometry. Human myeloid-derived suppressor cells (MDSCs) treated with 10 ng/mL Recombinant Human IL-6. 100 Tests Log in to see 26至31个工作日
¥2,787.23
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小鼠 Allophycocyanin FACS Detection of Indoleamine 2,3-dioxygenase/IDO in Human MDSCs by Flow Cytometry. Human PBMC-derived myeloid-derived suppressor cells (MDSCs) treated with 10 ng/mL Recombinant Human IL-6. 100 Tests Log in to see 26至31个工作日
¥2,915.87
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小鼠 非结合性 FACS, ICC Indoleamine 2,3-dioxygenase/IDO in A431 Human Cell Line. Indoleamine 2,3-dioxygenase/IDO was detected in immersion fixed A431 human epithelial carcinoma cells stimulated with 0.5 ng/mL of Recombinant Human IFN-gamma. Specific staining was localized to cytoplasm. Detection of Indoleamine 2,3-dioxygenase/IDO in Human MDSCs by Flow Cytometry. Human PBMC-derived myeloid-derived suppressor cells (MDSCs) treated with 10 ng/mL Recombinant Human IL-6. To facilitate intracellular staining, cells were fixed with paraformaldehyde and permeabilized with saponin. 100 μg Log in to see 26至31个工作日
¥2,178.33
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小鼠 非结合性 IHC (fro), IHC (p), WB   0.1 mg Log in to see 29至35个工作日
¥4,388.90
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绵羊 非结合性 EIA, FACS, IF, IHC (p), WB   0.1 mg Log in to see 29至35个工作日
¥4,489.84
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通过反应活性、应用领域、克隆类型和共轭标记 IDO1 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-Indoleamine 2,3-Dioxygenase 1 抗体

  1. Human Polyclonal IDO1 Primary Antibody for IF (cc), IF (p) - ABIN1714836 : Fu, Zhang, Song, Sheng, Li, Li, Song, Wang, Chu, Wei: Effect of bone marrow-derived CD11b(+)F4/80 (+) immature dendritic cells on the balance between pro-inflammatory and anti-inflammatory cytokines in DBA/1 mice with collagen-induced arthritis. in Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2014 (PubMed)
    Show all 2 references for ABIN1714836

  2. Human Polyclonal IDO1 Primary Antibody for EIA, FACS - ABIN1107630 : Grohmann, Fallarino, Puccetti: Tolerance, DCs and tryptophan: much ado about IDO. in Trends in immunology 2003 (PubMed)
    Show all 2 references for ABIN1107630

  3. Human Polyclonal IDO1 Primary Antibody for IHC (p), WB - ABIN389194 : Maghzal, Thomas, Hunt, Stocker: Cytochrome b5, not superoxide anion radical, is a major reductant of indoleamine 2,3-dioxygenase in human cells. in The Journal of biological chemistry 2008 (PubMed)
    Show all 2 references for ABIN389194

  4. Human Polyclonal IDO1 Primary Antibody for EIA, IHC (p) - ABIN357869 : Scheler, Wenzel, Tüting, Takikawa, Bieber, von Bubnoff: Indoleamine 2,3-dioxygenase (IDO): the antagonist of type I interferon-driven skin inflammation? in The American journal of pathology 2007 (PubMed)
    Show all 2 references for ABIN357869

  5. Human Polyclonal IDO1 Primary Antibody for IF, IHC - ABIN185488 : Munn, Sharma, Baban, Harding, Zhang, Ron, Mellor: GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase. in Immunity 2005 (PubMed)

  6. Mouse (Murine) Polyclonal IDO1 Primary Antibody for IHC (fro), IHC (p) - ABIN1107631 : Hill, Pereira, Chauveau, Zagani, Remy, Tesson, Mazal, Ubillos, Brion, Asghar, Ashgar, Mashreghi, Kotsch, Moffett, Doebis, Seifert, Boczkowski, Osinaga, Anegon: Heme oxygenase-1 inhibits rat and human breast cancer cell proliferation: mutual cross inhibition with indoleamine 2,3-dioxygenase. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005 (PubMed)

  7. Mouse (Murine) Monoclonal IDO1 Primary Antibody for FACS, IP - ABIN1043734 : Mellor, Munn: IDO expression by dendritic cells: tolerance and tryptophan catabolism. in Nature reviews. Immunology 2004 (PubMed)

更多抗Indoleamine 2,3-Dioxygenase 1的相互作用对抗体

Cow (Bovine) Indoleamine 2,3-Dioxygenase 1 (IDO1) interaction partners

  1. Differential expression of CD25 (显示 IL2RA 抗体) and IDO mRNA with high and low virulence bovine viral diarrhea virus might reflect temporal differences in transcription during the immune response elicited by these viral strains.

  2. IDO may be involved in downregulating immune responses to M. avium subsp. paratuberculosis and other virulent mycobacteria, which may be an example of the pathogen harnessing host immunoregulatory pathways to aid survival.

  3. INDO participates in IFN-gama-induced death of bovine luteal cells, through a mechanism that involves degradation of tryptophan, thereby reducing tryptophan concentrations to a point insufficient to meet luteal cells needs

Rhesus Monkey Indoleamine 2,3-Dioxygenase 1 (IDO1) interaction partners

  1. SIV-infected macaques exhibiting progression to AIDS displayed greater expression of TGF-beta (显示 TGFB1 抗体) and indoleamine 2,3 dioxygenase in CD8 (显示 CD8A 抗体)+ T cells from mesentric lymph nodes.

Human Indoleamine 2,3-Dioxygenase 1 (IDO1) interaction partners

  1. IDO gene expression is a feature of aggressive non-muscle-invasive urothelial cell bladder carcinoma, suggesting a potential immunosuppressive role of IDO

  2. Data show that in the absence of indoleamine 2,3-dioxygenase (IDO) inhibition, fatty acid oxidation increased along with increased activity of carnitine palmitoyltransferase I (CPT1 (显示 CPT1A 抗体)).

  3. High IDO1 expression is associated with cervical cancer.

  4. PSG stimulated IDO activity under the conditions of induction of the monocytes by interferon-gamma (显示 IFNG 抗体).

  5. These results indicate that the level of IDO expression may be associated with pregnancy-related complications, such as URSA, by affecting trophoblast cell proliferation and migration via the STAT3 (显示 STAT3 抗体) signaling pathway.

  6. IDO is a potential prognostic biomarker for overall survival of patients with gastric adenocarcinoma after gastrectomy.

  7. IDO expressed by placenta cells can down-regulate NKp46 (显示 NCR1 抗体) and NKG2D (显示 KLRK1 抗体) expression and reduce cytotoxicity in NK cells, suggesting an important role for IDO in the maintenance of normal pregnancy

  8. Results suggest that IDO expression is implicated in immunosuppression and tumor progression in glioma cells; combining IDO inhibition with standard TMZ treatment could be an encouraging therapeutic strategy for patients with malignant glioma

  9. Results suggest Withaferin A (WA) as a valuable small ligand molecule with strong binding affinity toward indoleamine 2,3-dioxygenase (IDO).

  10. Our results imply the probability of involvement of IDO in development of tolerance process, and we presume that high IDO activity is associated with nonresponsiveness to food allergens despite allergen sensitization.

Mouse (Murine) Indoleamine 2,3-Dioxygenase 1 (IDO1) interaction partners

  1. this study shows that IDO overexpression in dendritic cells attenuates acute allograft rejection

  2. This insight into IDO1's involvement in pro-tumorigenic inflammatory neovascularization may have important ramifications for IDO1 inhibitor development, not only in cancer where clinical trials are currently ongoing, but in other disease indications associated with neovascularization as well.

  3. Inhibition of IDO activity ameliorated Japanese encephalitis via enhancement of antiviral IFN-I/II innate and adaptive T-cell responses and increased central nervous system infiltration of peripheral leukocytes.

  4. Results suggest that IDO expression is implicated in immunosuppression and tumor progression in glioma cells; combining IDO inhibition with standard TMZ treatment could be an encouraging therapeutic strategy for patients with malignant glioma

  5. Data show that the expression of indoleamine 2, 3-dioxygenase 1 (IDO) was decreased after tumor cells were infected with Salmonella.

  6. Severity of sodium dodecyl sulfate-induced colitis is reduced in Ido1-deficient mice with down-regulation of TLR-MyD88 (显示 MYD88 抗体)-NF-kB transcriptional networks.

  7. IDO1 deficiency does not affect inflammation in Systemic Juvenile Idiopathic Arthritis, Secondary Hemophagocytic Lymphohistiocytosis and a T cell-triggered cytokine release model.

  8. Data indicate that indolamine-2,3-dioxygenase (IDO) and Fibroblast activation protein alpha (显示 FAP 抗体) (FAPalpha) were detectable in B16 melanoma tumor-bearing mice.

  9. Increased expression of IDO in liver cell adenomas compared to the surrounding normal tissue may create a microenvironment that promotes the progression of HCC (显示 FAM126A 抗体) by suppressing the proliferation of cytotoxic T lymphocytes and enhancing Tregs.

  10. Chimeric vaccine stimulation of human dendritic cell IDO1 occurs via the non-canonical NF-kappaB (显示 NFKB1 抗体) pathway.

Pig (Porcine) Indoleamine 2,3-Dioxygenase 1 (IDO1) interaction partners

Indoleamine 2,3-Dioxygenase 1 (IDO1) 抗原简介

蛋白简介

This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.

Gene names and symbols associated with IDO1

  • indoleamine 2,3-dioxygenase 1 (IDO1) 抗体
  • indoleamine 2,3-dioxygenase 1 (ido1) 抗体
  • indoleamine 2,3-dioxygenase 1 (Ido1) 抗体
  • indoleamine 2,3-dioxygenase 1-like (LOC100050681) 抗体
  • cd107b 抗体
  • Ido 抗体
  • IDO-1 抗体
  • IDO1 抗体
  • Indo 抗体

Protein level used designations for IDO1

indoleamine-pyrrole 2,3 dioxygenase , indoleamine 2,3-dioxygenase 2 , proto-IDO , putative indoleamine 2,3-dioxygenase , indoleamine 2,3-dioxygenase 1 , indolamine 2,3 dioxygenase , indole 2,3-dioxygenase , indoleamine-pyrrole 2,3-dioxygenase , IDO-1 , indoleamine 23-dioxygenase

GENE ID SPECIES
506281 Bos taurus
100037099 Xenopus laevis
100086385 Ornithorhynchus anatinus
448488 Xenopus (Silurana) tropicalis
464134 Pan troglodytes
571967 Danio rerio
574370 Macaca mulatta
100032999 Monodelphis domestica
100196903 Ovis aries
3620 Homo sapiens
15930 Mus musculus
66029 Rattus norvegicus
475574 Canis lupus familiaris
100519877 Sus scrofa
100050681 Equus caballus
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