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IER5 encodes a protein that is similar to other immediate early response proteins. 再加上，我们可以发IER5 抗体 (71) 和 IER5 蛋白 (4)和数多这个蛋白质的别的产品。
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Authors propose the GCF (显示 GUCY2F ELISA试剂盒) regulated transcriptional activity, at least in part, contributed to the upregulation of IER5 on radiation in HepG2 cells. The present findings provide insights into understanding the regulatory mechanisms of IER5.
These results reveal the existence of a novel IER5-mediated cancer regulation pathway that is responsible for the activation of HSF1 (显示 HSF1 ELISA试剂盒) observed in various cancers.
IER5 functions as a positive feedback regulator of HSF1 (显示 HSF1 ELISA试剂盒) and that this process involves PP2A (显示 PPP2R4 ELISA试剂盒)/B55 (显示 MINK1 ELISA试剂盒) and HSF1 (显示 HSF1 ELISA试剂盒) dephosphorylation.
These observations suggest that HSF1 (显示 HSF1 ELISA试剂盒)-mediated IER5 expression is involved in the expression of chaperone genes and in recovery from thermal stress.
Transcriptional repression mediated by IER5 regulates Cdc25B (显示 CDC25B ELISA试剂盒) expression levels via the release of NF-YB (显示 NFYB ELISA试剂盒) and p300 (显示 EP300 ELISA试剂盒) in acute myeloid leukemia (显示 BCL11A ELISA试剂盒).
the early radiation-induced expression of IER5 affects radiosensitivity via disturbing radiation-induced cell cycle checkpoints
Studies in rat found higher mRNA levels after waking and sleep deprivation for immediate early (显示 JUN ELISA试剂盒) genes/transcription factors such as IER5
This gene encodes a protein that is similar to other immediate early response proteins. In the mouse, a similar gene may play an important role in mediating the cellular response to mitogenic signals. Studies in rats found the expression of a similar gene to be increased after waking and sleep deprivation.
immediate early response gene 5 protein
, immediately early response
, immediate early response 5