anti-Hermansky-Pudlak Syndrome 5 (HPS5) 抗体

HPS5 encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. 再加上,我们可以发HPS5 试剂盒 (12)HPS5 蛋白 (4)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
HPS5 11234 Q9UPZ3
HPS5 308598  
HPS5 246694 P59438
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antibodies-online.cn销售最多的anti-HPS5 抗体

Showing 10 out of 27 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 WB HPS5 Antibody (N-term) (ABIN1881436) western blot analysis in NCI-H292 cell line lysates (35 µg/lane). This demonstrates the HPS5 antibody detected the HPS5 protein (arrow). 400 μL Log in to see 10至11个工作日
$324.50
详细
非结合性 ELISA, WB   200 μL Log in to see 7至9个工作日
$793.83
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HRP ELISA, WB   200 μL Log in to see 7至9个工作日
$1,013.83
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Biotin ELISA, WB   200 μL Log in to see 7至9个工作日
$1,013.83
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Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 7至9个工作日
$1,013.83
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APC ELISA, WB   200 μL Log in to see 7至9个工作日
$1,013.83
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FITC ELISA, WB   200 μL Log in to see 7至9个工作日
$1,013.83
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PE ELISA, WB   200 μL Log in to see 7至9个工作日
$1,013.83
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非结合性 IF, IHC, WB   100 μL Log in to see 16 Days
$460.63
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非结合性 ELISA, WB   200 μL Log in to see 11至16个工作日
$594.00
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通过反应活性、应用领域、克隆类型和共轭标记 HPS5 抗体

特性 应用范围 宿主 克隆类型 标记
Human


, , , , ,
Rat (Rattus)


Mouse (Murine)


引用最多的anti-HPS5 抗体

  1. Human Polyclonal HPS5 Primary Antibody for WB - ABIN1881436 : Helip-Wooley, Westbroek, Dorward, Koshoffer, Huizing, Boissy, Gahl: Improper trafficking of melanocyte-specific proteins in Hermansky-Pudlak syndrome type-5. in The Journal of investigative dermatology 2007 (PubMed)
    Show all 5 Pubmed References

更多抗HPS5的相互作用对抗体

Human Hermansky-Pudlak Syndrome 5 (HPS5) interaction partners

  1. We report a 92-year-old man with HPS 5 who, to our knowledge, is the oldest patient with HPS (显示 HPS1 抗体) documented in the literature.

  2. Seven mutations (six previously unreported) were described in the HPS1 (显示 HPS1 抗体), HPS4 (显示 HPS4 抗体), and HPS5 genes among Hermansky-Pudlak Syndrome patients of Mexican, Uruguayan, Honduran, Cuban, Venezuelan, and Salvadoran ancestries.

  3. Component of BLOC-2 (显示 HPS6 抗体). Results suggest a common biological basis underlying the pathogenesis of HPS-3 (显示 HPS3 抗体), -5 and -6 disease.

  4. LAMP-3 (显示 CD63 抗体) distribution was restricted to the perinuclear region in HPS-5 fibroblasts, instead of extending to the periphery

  5. Tyrosinase (显示 TYR 抗体) and TYRP1 (显示 TYRP1 抗体) are mistrafficked, however, and fail to be efficiently delivered to melanosomes of HPS-5 melanocytes

Zebrafish Hermansky-Pudlak Syndrome 5 (HPS5) interaction partners

  1. The snw/hps5I76N mutant provides a valuable resource for structure-function analyses of Hps5 and enables further elucidation of the molecular and cellular mechanisms underlying HPS (显示 AP3B1 抗体).

Mouse (Murine) Hermansky-Pudlak Syndrome 5 (HPS5) interaction partners

  1. Effects of the ru2(d) allele on pheomelanin synthesis were investigated.

  2. These results suggest that the ru2(d) allele suppresses the differentiation of melanocytes through the inhibition of eumelanin synthesis, but stimulates pheomelanin synthesis in melanocytes.

  3. These results suggest that the ru2(d) allele inhibits melanocyte differentiation, and that its impaired differentiation is rescued by excess tyrosine.

HPS5 抗原简介

蛋白简介

This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. This protein interacts with Hermansky-Pudlak syndrome 6 protein and may interact with the cytoplasmic domain of integrin, alpha-3. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 5. Multiple transcript variants encoding two distinct isoforms have been identified for this gene.

Gene names and symbols associated with HPS5

  • HPS5, biogenesis of lysosomal organelles complex 2 subunit 2 (HPS5) 抗体
  • HPS5, biogenesis of lysosomal organelles complex 2 subunit 2 (Hps5) 抗体
  • Hermansky-Pudlak syndrome 5 (hps5) 抗体
  • Aa2-028 抗体
  • Ab1-018 抗体
  • AI646796 抗体
  • AIBP63 抗体
  • AL022647 抗体
  • C85120 抗体
  • haze 抗体
  • hz 抗体
  • maroon 抗体
  • mr 抗体
  • ru-2 抗体
  • ru2 抗体
  • zgc:162420 抗体

Protein level used designations for HPS5

Hermansky-Pudlak syndrome 5 protein , alpha integrin binding protein 63 , alpha-integrin-binding protein 63 , ruby-eye protein 2 homolog , Hermansky-Pudlak syndrome 5 , Hermansky-Pudlak syndrome 5 protein homolog , ruby eye 2 , ruby-eye protein 2

GENE ID SPECIES
11234 Homo sapiens
308598 Rattus norvegicus
423079 Gallus gallus
510165 Bos taurus
100036709 Xenopus (Silurana) tropicalis
100037388 Danio rerio
100049701 Sus scrofa
100446504 Pongo abelii
100549976 Meleagris gallopavo
100616949 Monodelphis domestica
246694 Mus musculus
100716300 Cavia porcellus
101119945 Ovis aries
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