Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9) ELISA试剂盒

HSPA9 encodes a member of the heat shock protein 70 gene family. 再加上,我们可以发HSPA9 抗体 (176)HSPA9 蛋白 (14)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
 HSPA9 HSPA9 3313 P38646
小鼠 HSPA9 HSPA9 15526 P38647
大鼠 HSPA9 HSPA9 291671  
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Xenopus laevis Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9) interaction partners

  1. Hspa9 is an important mediator for pronephros development through modulation of pax8 (显示 PAX8 ELISA试剂盒). Mitochondrial functions of hspa9 are likely to be involved in specification of pronephric cell fate.

Human Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9) interaction partners

  1. mortalin (HSPA9) directly interacts with PP1alpha (显示 PPP1CA ELISA试剂盒) and MEK1 (显示 MAP2K1 ELISA试剂盒)/2 and facilitates PP1alpha (显示 PPP1CA ELISA试剂盒)-mediated dephosphorylation of MEK1 (显示 MAP2K1 ELISA试剂盒)/2 by promoting their physical interaction, which is important in determining cellular steady-state levels of phosphorylated MEK1 (显示 MAP2K1 ELISA试剂盒)/2 and, subsequently, MEK (显示 MAP2K1 ELISA试剂盒)/ERK (显示 EPHB2 ELISA试剂盒) activity.

  2. Identify Mortalin as a significant independent prognostic factor, in addition to location, clinical stage, and perineural invasion, for survival of pancreatic ductal adenocarcinoma patients.

  3. these findings indicate that reduced levels of HSPA9 may contribute to TP53 (显示 TP53 ELISA试剂盒) activation and increased apoptosis observed in del(5q)-associated MDS (显示 PAFAH1B1 ELISA试剂盒).

  4. phosphorylation by ERK (显示 EPHB2 ELISA试剂盒) also regulates the association of HIF-1alpha (显示 HIF1A ELISA试剂盒) with a so-far-unknown interaction partner identified as mortalin (also known as GRP75 and HSPA9), which mediates non-genomic involvement of HIF-1alpha (显示 HIF1A ELISA试剂盒) in apoptosis.

  5. mortalin is an oncogenic factor.

  6. endocytosis vesicle enrichment of GRP75 by mitochondria trafficking upregulates clathrin-independent endocytosis through an actin cytoskeleton reorganization mechanism mediated by the concurrent activation of Cdc42 (显示 CDC42 ELISA试剂盒) and RhoA (显示 RHOA ELISA试剂盒).

  7. Mortalin is up-regulated in non-small cell lung cancer, and it may be a potential biomarker of prognostic evaluation and a molecular therapeutic target for patients with early stage of non-small cell lung cancer

  8. the mitochondrial stress chaperone mortalin is crucial for melanogenesis. the hyperpigmented keloid skin possesses significantly higher level of mortalin expression. mortalin is increased during oxidative stress and drug-induced melanogenesis. overexpression of mortalin causes an increase in pigmentation and its compromise leads to reduction in melanin content.

  9. These findings suggest a regulatory role of human miRNA pathway especially GRP75 protein and hsa (显示 CD24 ELISA试剂盒)-mir (显示 MLXIP ELISA试剂盒)-126 in dengue virus replication.

  10. UBXN2A binds to mortalin's binding pocket within the substrate-binding domain of mortalin. UBXN2A increases stability of p53 protein targeted by the mortalin-CHIP E3 ubiquitin ligase.

Mouse (Murine) Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9) interaction partners

  1. Thus Hspa9 regulates erythroid differentiation through ISC cluster assembly, providing a pathophysiological mechanism for an MDS (显示 MECOM ELISA试剂盒) subtype characterized by HSPA9 haploinsufficiency

  2. This study demonstred that Mortalin expression in brain astrocytes.

  3. data imply a role for Hspa9 in B lymphopoiesis and Stat5 (显示 STAT5A ELISA试剂盒) activation downstream of IL-7 (显示 IL7 ELISA试剂盒) signaling

  4. Matrin 3 (显示 MATR3 ELISA试剂盒) interacts specifically with the heat shock proteins glucose-regulated protein 78 (显示 HSPA5 ELISA试剂盒), GRP75 and glutathione S-transferase (显示 GSTa2 ELISA试剂盒) pi isoform 2.

  5. down-regulation of mortalin may potentiate Abeta (显示 APP ELISA试剂盒)-mediated mitochondrial fragmentation and dysfunction in AD.

  6. the mortalin/DJ-1 (显示 PARK7 ELISA试剂盒) complex guards against mitochondrial oxidative stress and is indispensable for the maintenance of hematopoietic stem cells

  7. Inflammatory response of microglial cells includes a glycolytic shift and is modulated by mitochondrial glucose-regulated protein (显示 HSP90B1 ELISA试剂盒) 75/mortalin.

  8. Knockdown of Hspa9 results in a decrease in hematopoietic progenitors resulting in myelodysplastic syndromes.

  9. Data show that RNAi-mediated down-regulation of GRP75 and GRP75-blocking antibodies, both of which inhibited macromolecular endocytosis.

  10. The asymmetric segregation of mortalin in the bipotent cell line and its uniform distribution in a committed, lineage-restricted cell line raises the possibility that it may play a role in cell fate determination

HSPA9 抗原简介

Antigen Summary

This gene encodes a member of the heat shock protein 70 gene family. The encoded protein is primarily localized to the mitochondria but is also found in the endoplasmic reticulum, plasma membrane and cytoplasmic vesicles. This protein is a heat-shock cognate protein. This protein plays a role in cell proliferation, stress response and maintenance of the mitochondria. A pseudogene of this gene is found on chromosome 2.

Gene names and symbols associated with HSPA9

  • heat shock protein family A (Hsp70) member 9 S homeolog (hspa9.S) 抗体
  • heat shock protein family A (Hsp70) member 9 (hspa9) 抗体
  • stress-70 protein, mitochondrial (LOC577721) 抗体
  • heat shock protein family A (Hsp70) member 9 (HSPA9) 抗体
  • heat shock protein 9 (Hspa9) 抗体
  • heat shock protein family A member 9 (Hspa9) 抗体
  • heat shock protein family A (Hsp70) member 9 (Hspa9) 抗体
  • 74kDa 抗体
  • Csa 抗体
  • GRP-75 抗体
  • Grp75 抗体
  • Hsc74 抗体
  • Hsp74 抗体
  • Hsp74a 抗体
  • hspa9 抗体
  • Hspa9a 抗体
  • HSPA9B 抗体
  • Mortalin 抗体
  • MOT 抗体
  • Mot-2 抗体
  • Mot2 抗体
  • Mthsp70 抗体
  • MTHSP75 抗体
  • Pbp74 抗体

Protein level used designations for HSPA9

heat shock 70kDa protein 9 (mortalin) , heat shock 70kDa protein 9B , Stress-70 protein, mitochondrial-like protein , heat shock 70 kDa protein 9B , stress-70 protein, mitochondrial , GRP-75 , heat shock 70 kDa protein 9 , 75 kDa glucose-regulated protein , stress-70 protein, mitochondrial-like , heat shock 70kD protein 9B , mortalin, perinuclear , mortalin-2 , p66-mortalin , peptide-binding protein 74 , GRP 75 , heat shock 70kDa protein 9B (mortalin-2) , C3H-specific antigen , heat shock protein 9A , heat shock protein cognate 74 , heat shock protein, 74 kDa, A , heat shock protein, A , p66 MOT , PBP74 , heat shock 70kDa protein 9A , mortalin , mtHSP70 , 70 kDa heat shock protein , Heat shock 70 kDa protein 9

GENE ID SPECIES
379314 Xenopus laevis
407910 Xenopus (Silurana) tropicalis
577721 Strongylocentrotus purpuratus
714506 Macaca mulatta
100020208 Monodelphis domestica
100034032 Equus caballus
100173869 Pongo abelii
100406895 Callithrix jacchus
100521183 Sus scrofa
100590864 Nomascus leucogenys
416183 Gallus gallus
3313 Homo sapiens
517535 Bos taurus
474697 Canis lupus familiaris
15526 Mus musculus
291671 Rattus norvegicus
100689405 Cricetulus griseus
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