anti-Heat Shock 70kDa Protein 8 (HSPA8) 抗体

HSPA8 encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. 再加上,我们可以发HSPA8 试剂盒 (30)HSPA8 蛋白 (25)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
HSPA8 3312 P11142
大鼠 HSPA8 HSPA8 24468 P63018
HSPA8 15481 P63017
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antibodies-online.cn销售最多的anti-HSPA8 抗体

Showing 10 out of 268 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 IHC, WB <b>WB Suggested Anti-HSPA8 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>293T cell lysate <b>Sample type:</b> rat brain lysate<br><b>Primary Dilution: </b>1:1000<br><b>Image Submitted By:</b> Jennifer Morgan, PhD &, David Busch<br>University of Texas in Austin 100 μL Log in to see 2至3个工作日
$289.00
详细
山羊 非结合性 IHC, WB <b>WB Suggested Anti-HSPA8 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>COLO205 cell lysate <b>Sample Type:</b> 1. Lamprey CNS (20ug)<br>2. Rat Brain Lysate (20ug) <br><b>Primary Dilution: </b>1:1000<br><b>Secondary Antibody: </b>Goat anti-Rabbit HRP<br><b>Secondary Dilution:</b> 1:4000<br><b>Image Submitted by: </b>Jennifer Morgan, PhD &, David Busch<br>University of Texas in Austin 100 μL Log in to see 2至3个工作日
$289.00
详细
小鸡 非结合性 IC, IF, IP, WB Immunofluorescent analysis of HSC70 staining in NIH3T3 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Western blot analysis of HSC70 expression in HeLa (A), NIH3T3 (B) whole cell lysates. 200 μL Log in to see 13至14个工作日
$487.50
详细
非结合性 FACS, IF, IHC (p), WB Formalin-fixed and paraffin-embedded human brain tissue reacted with HSPA8 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Western blot analysis of HSPA8 Antibody (N-term) (ABIN650754) in Hela cell line lysates (35 µg/lane). HSPA8 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10至11个工作日
$324.50
详细
山羊 非结合性 ELISA, WB NB100- (2?g/ml) staining of A431 cell lysate (35?g protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Western Blot: HSPA8/HSC71/Hsc70 Antibody [ABIN1885497] - Analysis of HSPA8 in A431 cell lysate using this antibody at 2 ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7至9个工作日
$408.19
详细
非结合性 IHC (p), WB 100 μg Log in to see 4至6个工作日
$240.00
详细
山羊 非结合性 ELISA, WB ABIN185659 (2µg/ml) staining of A431 cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6至7个工作日
$326.89
详细
小鼠 非结合性 AA, Bind, ELISA, ICC, IF, IHC, IP, PLA, WB Hsc70 (1F2 H5) human cell line mix copy. 50 μg Log in to see 2至3个工作日
$220.00
详细
山羊 非结合性 EIA, WB   0.1 mg Log in to see 12至15个工作日
$375.38
详细
REACT_Artemia sp. 小鼠 非结合性 IF, IHC (fro), IP, WB   50 μg Log in to see 12至15个工作日
$375.38
详细

通过反应活性、应用领域、克隆类型和共轭标记 HSPA8 抗体

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引用最多的anti-HSPA8 抗体

  1. Hamster Polyclonal HSPA8 Primary Antibody for BI, ICC - ABIN361819 : Boorstein, Ziegelhoffer, Craig: Molecular evolution of the HSP70 multigene family. in Journal of molecular evolution 1994 (PubMed)
    Show all 13 Pubmed References

  2. Human Monoclonal HSPA8 Primary Antibody for AA, Bind - ABIN361800 : Bork, Sander, Valencia: An ATPase domain common to prokaryotic cell cycle proteins, sugar kinases, actin, and hsp70 heat shock proteins. in Proceedings of the National Academy of Sciences of the United States of America 1992 (PubMed)
    Show all 10 Pubmed References

  3. Human Polyclonal HSPA8 Primary Antibody for FACS, IF - ABIN1944844 : Tsukahara, Yoshioka, Muraki: Molecular and functional characterization of HSC54, a novel variant of human heat-shock cognate protein 70. in Molecular pharmacology 2000 (PubMed)
    Show all 2 Pubmed References

  4. Fish Polyclonal HSPA8 Primary Antibody for WB - ABIN361860 : Brown, Hong-Brown, Doxsey, Welch: Molecular chaperones and the centrosome. A role for HSP 73 in centrosomal repair following heat shock treatment. in The Journal of biological chemistry 1996 (PubMed)
    Show all 6 Pubmed References

  5. Human Polyclonal HSPA8 Primary Antibody for ELISA, WB - ABIN188549 : Zhang, Fan, Becker, Graff, Lee, Francomano: Comparison of gene expression profile between human chondrons and chondrocytes: a cDNA microarray study. in Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2006 (PubMed)

更多抗HSPA8的相互作用对抗体

Xenopus laevis Heat Shock 70kDa Protein 8 (HSPA8) interaction partners

  1. hsp72 (显示 HSPA1A 抗体) was more potent than hsc73 in generating protective immune responses against the class Ia-negative 15/0 tumors.

Human Heat Shock 70kDa Protein 8 (HSPA8) interaction partners

  1. Synapsin is part of a multiprotein complex enriched in chaperones/cochaperones including Hsc70. Hsc70 chaperone activity is required for the cytosolic slow axonal transport of synapsin.

  2. study demonstrates a critical role of Hsc70 in SV40 endoplasmic reticulum-to-cytosol penetration and reveal how SGTA (显示 SGTA 抗体) controls Hsc70 to impact this process

  3. In fact, DnaJC5 (显示 DNAJC5 抗体) overexpression induced tau release in cells, neurons, and brain tissue, but only when activity of the chaperone Hsc70 was intact and when tau was able to associate with this chaperone.

  4. HSPA1A (显示 HSPA1A 抗体) and HSPA8 have roles in parturition through stimulating immune inflammatory and estrogen response

  5. These results suggest that Bag1 (显示 BAG1 抗体) and Bag3 (显示 BAG3 抗体) control the stability of the Hsc70-client complex using at least two distinct protein-protein contacts, providing a previously under-appreciated layer of molecular regulation in the human Hsc70 system.

  6. While cerebrospinal fluid Nrf2 (显示 GABPA 抗体) and HSPA8 do not appear to offer diagnostic biomarkers for Parkinson's disease (PD), the associations between Nrf2 (显示 GABPA 抗体) levels and UPDRS scores in LRRK2 (显示 LRRK2 抗体) + PD patients merit further investigation

  7. HSPA8 maintains pluripotency of human pluripotent stem cells by binding to the master pluripotency regulator OCT4 (显示 POU5F1 抗体) and facilitating its DNA-binding activity.

  8. heat shock cognate 70 (HSC70) is an essential component of Aes (显示 AES 抗体) foci in colorectal cancer cells.

  9. Cx43 (显示 GJA1 抗体)-Hsc70 interaction regulates cell cycle G1/S progression through a novel mechanism by which Cx43 (显示 GJA1 抗体)-Hsc70 interaction prevents the nuclear accumulation of p27 (显示 PAK2 抗体) through controlling the nuclear translocation of cyclin D1 (显示 CCND1 抗体)-CDK4 (显示 CDK4 抗体)-p27 (显示 PAK2 抗体) complex.

  10. serum HSC71 was identified as a novel serum biomarker of renal cell carcinoma (显示 MOK 抗体), particularly useful in early diagnosis of clear-cell type.

Cow (Bovine) Heat Shock 70kDa Protein 8 (HSPA8) interaction partners

  1. Single-particle fluorescence imaging tracks the dynamics of Hsc70 and its clathrin substrate in real time.

  2. The interaction of the molecular chaperone (显示 HSP90AA1 抗体) Hsc70 (HSPA8) with recombinant PrP (显示 PRNP 抗体) was investigated.

  3. Structure of clathrin coat with bound Hsc70 and auxilin (显示 DNAJC6 抗体).

  4. specific association between HSP73 and gentamicin may reduce the chaperone activity of HSP73 in vitro and/or in vivo

  5. report role of HSC70 in the regulation of NMT

  6. studied the process of disassembly by using cryo-electron microscopy to identify the initial binding site of Hsc70 on clathrin-C58J baskets at pH 6, under which conditions disassembly does not proceed further. Hsc70 interactions involve two sites

  7. Coats assembled from recombinant clathrin are good substrates for ATP- and auxilin (显示 DNAJC6 抗体)-dependent, Hsc70-catalyzed uncoating.

  8. The structure of an Hsp110 (显示 HSPH1 抗体):Hsc70 nucleotide exchange complex, is reported.

  9. analysis of the formation of a stable complex between chaperonin-containing TCP-1 (显示 CCT6A 抗体) (CCT (显示 TCP1 抗体)) and Hsc70

  10. Elevated expression of bovine heat shock cognate (hsc)70 protein increases diabetes and inflammation following islet beta cell damage in a transgenic mouse model.

Mouse (Murine) Heat Shock 70kDa Protein 8 (HSPA8) interaction partners

  1. Synapsin is part of a multiprotein complex enriched in chaperones/cochaperones including Hsc70. Hsc70 chaperone activity is required for the cytosolic slow axonal transport of synapsin.

  2. Hsc70 interacts with FILIP to mediate its effects on non-muscle myosin IIb (显示 MYH10 抗体) and to regulate spine morphology

  3. HSPA1A (显示 HSPA1A 抗体) and HSPA8 have roles in parturition through stimulating immune inflammatory and estrogen response

  4. intracellular Salmonella recruit the host proteins LAMP-2A and Hsc73, key components of the host protein turnover pathway known as chaperone-mediated autophagy involved in transport of cytosolic proteins to the lysosome for degradation.

  5. these data demonstrate a novel interaction between Hsc70 and TH that regulates the activity and localization of the enzyme to synaptic vesicles, suggesting an important role for Hsc70 in dopamine homeostasis.

  6. C terminus of the hsc-70 LID domain as the structural interface interacting with endosomal Phosphatidylserine

  7. the association of MNSFbeta (显示 FAU 抗体) with HSPA8 may promote RANKL (显示 TNFSF11 抗体)-induced osteoclastogenesis.

  8. Hspa8 plays a vital role in genetic differences in responses to stress and ethanol and their interactions

  9. PTEN-like domains of GAK and auxilin are not essential for Hsc70-dependent chaperoning and uncoating of clathrin, but depending on the tissue, these domains appear to increase the efficiency of these co-chaperones.

  10. mass spectrometry-based proteomic analysis identified heat shock cognate 70 (HSC70) as a novel binding protein of FSP27 (显示 CIDEC 抗体)

HSPA8 抗原简介

蛋白简介

This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with HSPA8

  • heat shock protein family A (Hsp70) member 8 L homeolog (hspa8.L) 抗体
  • heat shock protein family A (Hsp70) member 8 (HSPA8) 抗体
  • heat shock protein family A (Hsp70) member 8 (Hspa8) 抗体
  • heat shock 70kDa protein 8 (HSPA8) 抗体
  • heat shock protein 8 (Hspa8) 抗体
  • heat shock protein 8 (hspa8) 抗体
  • 2410008N15Rik 抗体
  • HSC54 抗体
  • Hsc70 抗体
  • Hsc71 抗体
  • Hsc73 抗体
  • HSP71 抗体
  • Hsp73 抗体
  • Hspa10 抗体
  • LAP1 抗体
  • NIP71 抗体
  • wu:fb01g06 抗体
  • wu:fi48b06 抗体

Protein level used designations for HSPA8

LPS-associated protein 1 , N-myristoyltransferase inhibitor protein 71 , constitutive heat shock protein 70 , heat shock 70kd protein 10 , heat shock cognate 71 kDa protein , heat shock cognate protein 54 , lipopolysaccharide-associated protein 1 , Hsc70 ATPase , heat shock 70 kDa protein 8 , heat shock 70kd protein 10 (HSC71) , heat shock cognate 71 kD protein , Heat shock cognate protein 70 , heat shock 70kD protein 8 , heat shock protein 8 , heat shock protein A8 , heat shock cognate 70 , heat shock cognate 71 kDa protein-like protein , heat shock protein 70 cognate , heat shock cognate hsc73 , heat shock protein cognate 70 , heat shock 70kDa protein 8 , heat shock cognate 71-kd protein

GENE ID SPECIES
379319 Xenopus laevis
3312 Homo sapiens
281831 Bos taurus
24468 Rattus norvegicus
395853 Gallus gallus
479406 Canis lupus familiaris
100009679 Equus caballus
100172711 Pongo abelii
15481 Mus musculus
573376 Danio rerio
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