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HLA-DRB1 蛋白

(Major Histocompatibility Complex, Class II, DR beta 1 (HLA-DRB1))
HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa. It is encoded by 6 exons. Exon one encodes the leader peptide\; exons 2 and 3 encode the two extracellular domains\; exon 4 encodes the transmembrane domain\; and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogs DRB3, DRB4 and DRB5. DRB1 is present in all individuals. Allelic variants of DRB1 are linked with either none or one of the genes DRB3, DRB4 and DRB5. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9. [provided by RefSeq, Jul 2008].
HLA-DRB1 Protein (AA 30-266) (rho-1D4 tag) HLA-DRB1 Protein (AA 30-266) (rho-1D4 tag) HLA-DRB1 Protein (AA 30-266) (rho-1D4 tag) (ABIN3112900)

Crystallography grade HLA-DRB1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys

HLA-DRB1 Protein (AA 30-227) (His tag) HLA-DRB1 Protein (AA 30-227) (His tag) HLA-DRB1 Protein (AA 30-227) (His tag) (ABIN3087865)

Crystallography grade HLA-DRB1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys

HLA-DRB1 Protein (AA 30-227) (His tag) HLA-DRB1 Protein (AA 30-227) (His tag) HLA-DRB1 Protein (AA 30-227) (His tag) (ABIN3088174)

Crystallography grade HLA-DRB1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys

HLA-DRB1 蛋白 by Grade

Find HLA-DRB1 蛋白 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

HLA-DRB1 蛋白 by Origin

Find HLA-DRB1 蛋白 for a variety of species such as anti-Human HLA-DRB1, anti-Dog HLA-DRB1, anti-Mouse HLA-DRB1. The species listed below are among those available. Click on a link to go to the corresponding products.

HLA-DRB1 蛋白 by Source

Here you will find HLA-DRB1 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

HLA-DRB1 蛋白 by 蛋白类型

Here you can find HLA-DRB1 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

HLA-DRB1 蛋白 by 应用范围

Find HLA-DRB1 蛋白 validated for a specific application such as SDS, WB, ELISA, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular HLA-DRB1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3112900
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3087865
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3088174
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7412938
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7412935
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2722844
Quantity 20 μg
Datasheet Datasheet
Reactivity Dog
Source Yeast
Validations
Cat. No. ABIN1660811
Quantity 1 mg
Datasheet Datasheet

Aliases for HLA-DRB1 蛋白

major histocompatibility complex, class II, DR beta 1 (hla-drb1) 蛋白
major histocompatibility complex, class II, DR beta 1 (HLA-DRB1) 蛋白
DRB1 蛋白
DRw10 蛋白
HLA-DR1B 蛋白
HLA-DRB 蛋白
MGC108235 蛋白
SS1 蛋白
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