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E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. 再加上，我们可以发和数多这个蛋白质的别的产品。
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Ndel1 (显示 NDEL1 抗体) acts as a novel upstream regulator of the trichoplein-Aurora A (显示 AURKA 抗体) pathway to inhibit primary cilia assembly.
Ndel1 (显示 NDEL1 抗体) regulates Dyn2 (显示 DNM2 抗体) GTPase (显示 RACGAP1 抗体) activity and impacts GluR1 (显示 GRIA1 抗体)-containing membranes distribution in a manner reminiscent of Dyn2 (显示 DNM2 抗体).
These findings suggest that the human NEDL1 transgenic mice might develop Amyotrophic lateral sclerosis-like symptoms, showing signs of motor abnormalities, accompanied with significant reduction in muscle strength.
These findings suggest that RNF43 (显示 RNF43 抗体) is associated with p53 (显示 TP53 抗体)-mediated apoptosis in collaboration with NEDL1 in colorectal carcinogenesis.
interaction among misfolded SOD1 (显示 SOD1 抗体), NEDL1, translocon-associated protein-delta (显示 SSR4 抗体), and Dishevelled-1 (显示 DVL1 抗体) forms a ubiquitinated protein complex that is included in potentially cytotoxic protein aggregates
functional interaction of NEDL1 with p53 (显示 TP53 抗体) might contribute to the induction of apoptosis in cancerous cells bearing wild-type p53 (显示 TP53 抗体).
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.
E3 ubiquitin-protein ligase HECW1
, HECT type E3 ubiquitin ligase
, HECT, C2 and WW domain-containing protein 1
, NEDD4-like E3 ubiquitin-protein ligase 1
, NEDD4-like ubiquitin-protein ligase 1