anti-Guanidinoacetate N-Methyltransferase (GAMT) 抗体

The protein encoded by GAMT is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. 再加上,我们可以发GAMT 蛋白 (21)GAMT 试剂盒 (5)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
GAMT 14431 O35969
GAMT 2593 Q14353
GAMT 25257  

antibodies-online.cn销售最多的anti-GAMT 抗体

Showing 10 out of 49 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-GAMT Antibody Titration: 0.2-1 ug/mlPositive Control: Jurkat cell lysate WB Suggested Anti-GAMT  Antibody Titration: 0.2-1 µg/mL  Positive Control: Jurkat cell lysate  GAMT is supported by BioGPS gene expression data to be expressed in Jurkat 100 μL Log in to see 24至29个工作日
¥3,074.65
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非结合性 IHC, WB 100 μL Log in to see 24至29个工作日
¥3,074.65
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非结合性 WB 50 μg Log in to see 29至35个工作日
¥5,538.93
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非结合性 IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human hepatocellular carcinoma labeled with Anti-GAMT Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 14至17个工作日
¥2,610.23
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豚鼠 非结合性 WB 50 μg Log in to see 29至35个工作日
¥5,538.93
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非结合性 ELISA, WB 50 μg Log in to see 24至29个工作日
¥4,312.06
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非结合性 IC, IF, WB Immunofluorescent analysis of GAMT staining in U2OS cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody i Western blot analysis of GAMT expression in Jurkat (A), Hela (B), mouse liver (C), rat brain (D) whole cell lysates. 200 μL Log in to see 7至8个工作日
¥3,981.76
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非结合性 IF, IHC, WB Western blot analysis of extracts of various cell lines, using GAMT antibody. Immunofluorescence analysis of U20S cell using GAMT antibody. Blue: DAPI for nuclear staining. 100 μL Log in to see 34至38个工作日
¥2,882.69
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小鼠 非结合性 ELISA Detection limit for recombinant GST tagged GAMT is 1 ng/ml as a capture antibody. 100 μg Log in to see 29至34个工作日
¥3,169.73
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非结合性 IHC, IHC (p), WB Immunohistochemistry-Paraffin: GAMT Antibody [NBP2-14036] - Staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells. Western Blot: GAMT Antibody [NBP2-14036] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp.Lane 4: Human plasma (IgG/HSA depleted).Lane 5: Human liver tissue 0.1 mL Log in to see 28至35个工作日
¥3,591.24
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通过反应活性、应用领域、克隆类型和共轭标记 GAMT 抗体

特性 应用范围 宿主 克隆类型 标记
Mouse (Murine)


Human , ,
,
,
Rat (Rattus)


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引用最多的anti-GAMT 抗体

  1. Human Polyclonal GAMT Primary Antibody for IHC, WB - ABIN2775546 : Borini, Staiano, Rocchia, Rossi, Rossi, DAuria: Advanced nanotechnological approaches for designing protein-based "lab-on-chips" sensors on porous silicon wafer. in Recent patents on DNA & gene sequences 2008 (PubMed)
    Show all 2 references for 2775546

  2. Cow (Bovine) Polyclonal GAMT Primary Antibody for WB - ABIN2776937 : Komoto, Huang, Hu, Takata, Konishi, Ogawa, Gomi, Fujioka, Takusagawa: Crystallization and preliminary x-ray diffraction studies of guanidinoacetate methyltransferase from rat liver. in Acta crystallographica. Section D, Biological crystallography 2000 (PubMed)

更多抗GAMT的相互作用对抗体

Mouse (Murine) Guanidinoacetate N-Methyltransferase (GAMT) interaction partners

  1. Inactivation of the creatine kinase system by GAMT deficiency does not alter mitochondrial organization and intracellular compartmentation in relaxed cardiomyocytes.

  2. GAMT was expressed highly in oligodendrocytes and olfactory ensheathing glia and moderately in astrocytes, whereas GAMT was very low in neurons and microglia.

  3. despite the absence of Cr, GAMT-/- mice can cope with mild ischaemic stress by using phosphorylated guanidinoacetate for high energy phosphoryl transfer

  4. GAMT(Cr)-/- mice showed differences in maximal rates of force rise and relaxation times during the isometric protocol as well as in force during the dynamic protocol.

  5. Our results can provide the basis for additional experiments to optimize Cr supplementation in GAMT deficiency, as increases in brain Cr are slow in patients after Cr supplementation.

  6. GAMT and AGAT (显示 GATM 抗体) mRNA are up-regulated 5.4- and 1.9-fold respectively in adult mdx (显示 DMD 抗体) muscle compared to C57

  7. In the fetal brain, mRNA expression of GAMT was relatively low until 34 days gestation (term is 38-39 days). In the fetal kidney and liver, GAMT mRNA and protein expression were also relatively low until 34-37 days gestation.

Human Guanidinoacetate N-Methyltransferase (GAMT) interaction partners

  1. Data suggest that creatine is provided equally by diet and by endogenous synthesis from arginine and glycine with successive involvement of arginine glycine amidinotransferase [AGAT (显示 GATM 抗体)] and guanidinoacetate methyl transferase [GAMT]. [REVIEW]

  2. As early diagnosis results in normal neurodevelopmental outcome, GAMT deficiency should be included in newborn screening programs to diagnose individuals at the asymptomatic stage of the disease

  3. The estimated incidence of GAMT deficiency is 1:250,000 newborns based on our pilot study.

  4. Study reports six novel pathogenic mutations in GAMT gene in patients with Guanidinoacetate methyltransferase deficiency.

  5. Two novel heterozygous variants with sequence deletion and sequence insertion in the GAMT gene have been identified in newborns with guanidinoacetate methyltransferase deficiency.

  6. impact of creatine deficiency syndrome mutations, CRTR (显示 SLC6A8 抗体) and GAMT on metabolic stress was analyzed in patient fibroblast cultures

  7. GAMT genes may not be directly involved in human male infertility

  8. Mutations in the GAMT gene are responsible for GAMT deficiency, since overexpression of the GAMT open reading frame restores GAMT activity in GAMT-deficient fibroblasts.

  9. compound heterozygous mutations in the GAMT gene may be causitive in guanidinoacetate methyltransferase deficiency masquerading as a mitochondrial encephalopathy [case report]

  10. the carrier rate of the c.59G>C; p.Trp20Ser mutation in GAMT is relatively high in these islands, as well as in other parts of Portugal.

Zebrafish Guanidinoacetate N-Methyltransferase (GAMT) interaction partners

  1. The spatiotemporal expression pattern of gamt during zebrafish embryogenesis was revealed.

GAMT 抗原简介

蛋白简介

The protein encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene. Pseudogenes of this gene are found on chromosomes 2 and 13.

Gene names and symbols associated with GAMT

  • guanidinoacetate N-methyltransferase (gamt) 抗体
  • guanidinoacetate N-methyltransferase (GAMT) 抗体
  • Guanidinoacetate N-methyltransferase (gamt) 抗体
  • guanidinoacetate methyltransferase (Gamt) 抗体
  • guanidinoacetate N-methyltransferase (Gamt) 抗体
  • AA571402 抗体
  • CCDS2 抗体
  • GAMT 抗体
  • GMT 抗体
  • MGC75698 抗体
  • PIG2 抗体
  • Spintz1 抗体
  • TP53I2 抗体
  • zgc:123136 抗体

Protein level used designations for GAMT

guanidinoacetate N-methyltransferase , Guanidinoacetate N-methyltransferase , guanidinoacetate methyltransferase

GENE ID SPECIES
394491 Xenopus (Silurana) tropicalis
485085 Canis lupus familiaris
749982 Pan troglodytes
770737 Gallus gallus
100196494 Salmo salar
100528342 Ictalurus punctatus
14431 Mus musculus
2593 Homo sapiens
515270 Bos taurus
25257 Rattus norvegicus
796865 Danio rerio
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