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The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. 再加上，我们可以发Golgi Membrane Protein 1 抗体 (169) 和 Golgi Membrane Protein 1 蛋白 (36)和数多这个蛋白质的别的产品。
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Human GOLM1 ELISA Kit for Sandwich ELISA - ABIN414786
Kosanam, Prassas, Chrystoja, Soleas, Chan, Dimitromanolakis, Blasutig, Rückert, Gruetzmann, Pilarsky, Maekawa, Brand, Diamandis: Laminin, gamma 2 (LAMC2): a promising new putative pancreatic cancer biomarker identified by proteomic analysis of pancreatic adenocarcinoma tissues. in Molecular & cellular proteomics : MCP 2013
Both gain- and loss-of-function studies determine that GOLM1 acts as a key oncogene (显示 RAB1A ELISA试剂盒) by promoting HCC (显示 FAM126A ELISA试剂盒) growth and metastasis.
A cytokine QTL at the NAA35 (显示 MAK10 ELISA试剂盒)-GOLM1 locus markedly modulated interleukin (IL)-6 (显示 IL6 ELISA试剂盒) production in response to multiple pathogens and was associated with susceptibility to candidemia.
knock-down of GP73 down-regulates HCV infection and replication in Huh7-MAVSR cells and primary human hepatocytes
Studies indicate that golgi membrane protein 1 (GOLM1) may promote HCC (显示 FAM126A ELISA试剂盒) by regulation of epidermal growth factor receptor (EGFR (显示 EGFR ELISA试剂盒)) recycling, and suggest that therapeutic targeting of GOLM1 may be a potential strategy for combating hepatocellular carcinoma (HCC (显示 FAM126A ELISA试剂盒)) metastasis.
these studies revealed that GP73 promotes hepatitis C virus (HCV) secretion by directly mediating the interaction of ApoE (显示 APOE ELISA试剂盒) with HCV replication complex through binding with HCV NS5A.
Significantly higher serum levels of GP-73 and PIVKA-II were detected in the hepatocellular carcinoma patients than in controls.
The critical role of GP73 in hepatocellular carcinoma invasion, epithelial-mesenchymal transition and metastasis
Results show that overexpression of GP73 in hepatocellular carcinoma cell (HCC (显示 FAM126A ELISA试剂盒)) line retrieved the expression of epithelial-mesenchymal transition (EMT (显示 ITK ELISA试剂盒)) markers, and promoted cell motility and invasion. High expression of GP73 was also found in HCC (显示 FAM126A ELISA试剂盒) tissues with metastasis providing evidence for an important role of GP73 in HCC (显示 FAM126A ELISA试剂盒) metastasis.
Serum GP73 had limited diagnostic value for HBV-related liver cancer. The combined use of serum GP73 and AFP (显示 AFP ELISA试剂盒) levels improved the diagnostic efficacy.
GP73 enhances MMP-13 (显示 MMP13 ELISA试剂盒) expression through cAMP responsive element binding protein (CREB (显示 CREB1 ELISA试剂盒))-mediated transcription activation. Levels of GP73 and MMP-13 (显示 MMP13 ELISA试剂盒) are increased and positively correlated in human HCC (显示 FAM126A ELISA试剂盒) tissues. Augmented MMP-13 (显示 MMP13 ELISA试剂盒) potentiates HCC (显示 FAM126A ELISA试剂盒) cell metastasis.
Gorasp2 (显示 GORASP2 ELISA试剂盒)-/- mice suffered from spermatogenesis defects. Golgi morphology of spermatocytes was disturbed in Gorasp2 (显示 GORASP2 ELISA试剂盒)-/- mice. GRASP55 (显示 GORASP2 ELISA试剂盒) interacted via PDZ (显示 INADL ELISA试剂盒)-mediated interactions with JAMs.
GRASP55 (显示 GORASP2 ELISA试剂盒) responds to inflammasome stimulation,controls autophagy initiation and important for secretion of IL-1b (显示 IL1B ELISA试剂盒) and IL-18 (显示 IL18 ELISA试剂盒)
In Atp7b (显示 ATP7B ELISA试剂盒)(-/-) mice, GP73 mRNA was significantly elevated at 20-46 weeks of age, coincident with extensive hepatic inflammation and fibrosis.
The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a type II Golgi transmembrane protein. It processes proteins synthesized in the rough endoplasmic reticulum and assists in the transport of protein cargo through the Golgi apparatus. The expression of this gene has been observed to be upregulated in response to viral infection. Alternatively spliced transcript variants encoding the same protein have been described for this gene.
golgi membrane protein 1
, golgi phosphoprotein 2
, Golgi membrane protein 1
, golgi membrane protein GP73
, golgi protein, 73-kD
, Golgi reassembly-stacking protein 2
, golgi reassembly-stacking protein of 55 kDa