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GCM1 encodes a DNA-binding protein with a gcm-motif (glial cell missing motif). 再加上，我们可以发GCM1 抗体 (46) 和 GCM1 蛋白 (3)和数多这个蛋白质的别的产品。
chromosomal localization of the porcine GCM1 gene and the identification and characterization of a GCM1 associated microsatellite marker [GCM1]
results suggest that p45 NF-E2 (显示 NFE2 ELISA试剂盒) negatively regulates differentiation and apoptosis activation of human syncytiotrophoblast by modulating GCM1 acetylation and sumoylation.
Identify a novel cis (显示 CISH ELISA试剂盒)-acting sequence (-369 to -320) at the placental growth factor (显示 PGF ELISA试剂盒) promoter, which was critical for mediating the basal and DLX3 (显示 DLX3 ELISA试剂盒)/GCM1-dependent PGF (显示 PGF ELISA试剂盒) promoter activities.
Twist1 (显示 TWIST1 ELISA试剂盒) may promote trophoblast syncytialization by regulating the expression of GCM1.
GATA3 (显示 GATA3 ELISA试剂盒) knockdown elevated HtrA4 (显示 HTRA4 ELISA试剂盒) expression in BeWo and JEG-3 trophoblast cell lines and enhanced the invasion activities of both lines. This study uncovered a new GATA3 (显示 GATA3 ELISA试剂盒) function in placenta as a negative regulator of GCM1 activity and trophoblastic invasion.
GLI2 (显示 GLI2 ELISA试剂盒) stabilized glial cell missing-a, a pivotal transcriptional factor for trophoblastic syncytialization.
Gcm1 and Fzd5 function in an evolutionary conserved positive feedback loop that regulates trophoblast differentiation and sites of chorionic branching morphogenesis.
Results suggest that caspase-14 (显示 CASP14 ELISA试剂盒) may interact with GCM1 to participate in syncytiotrophoblast differentiation during placental development.
study reveals a novel function for RACK1 (显示 GNB2L1 ELISA试剂盒) to regulate GCM1 activity and placental cell migration and invasion
GCM1-directed villous trophoblast differentiation is repressed by DREAM
c-Myc (显示 MYC ELISA试剂盒)-regulated members of the miR-17~92 and miR (显示 MLXIP ELISA试剂盒)-106a~363 clusters inhibit trophoblast differentiation by repressing GCM1 and CYP19A1 (显示 CYP19A1 ELISA试剂盒).
Data show that the GCM1/syncytin-B pathway is significantly downregulated in the placenta of BCL9L (显示 BCL9L ELISA试剂盒)-deficient mice and that the fusion and differentiation of ST-II cells are blocked.
as in mice, fetoplacental vascularity increased when GCM1 protein expression decreased (R(2)=-0.45; P<0.05).
Gcm1 (glial cells missing 1) are involved in the epigenetic regulation of Hes5 (显示 HES5 ELISA试剂盒) transcription by DNA demethylation independently of DNA replication.
studies identify a novel function of p45NF-E2 (显示 NFE2 ELISA试剂盒) during placental development: in trophoblast cells, p45NF-E2 (显示 NFE2 ELISA试剂盒) represses Gcm1 and syncytiotrophoblast formation via acetylation
Gcm1 expression defines three stages of chorio-allantoic interaction during placental development
Brief ectopic expression of Gcm1 in mouse embryonic tail bud induces failure of the neural tube to close (spina bifida) and multiple neural tubes (diastematomyelia).
GCM domain as a new type of Zn-coordinating, sequence-specific DNA-binding domain.
mGCMa expression is primarily postnatal, arguing for a role in organ function rather than organ development
the shaping of the maternal blood spaces within the labyrinth was dependent on chorioallantoic morphogenesis and therefore disrupted in Gcm1 mutants
This gene encodes a DNA-binding protein with a gcm-motif (glial cell missing motif). The encoded protein is a homolog of the Drosophila glial cells missing gene (gcm). This protein binds to the GCM-motif (A/G)CCCGCAT, a novel sequence among known targets of DNA-binding proteins. The N-terminal DNA-binding domain confers the unique DNA-binding activity of this protein.
glial cells missing homolog 1 (Drosophila)
, chorion-specific transcription factor GCMa
, glial cells missing-like protein 1
, glial cells missing homolog a
, chorion-specific transcription factor GCMa-like
, GCM motif protein 1
, Gcm 1
, Gcm a
, glial cell deficient