anti-GTPase IMAP Family Member 3 (GIMAP3) 抗体

GIMAP3 encodes a mitochondrial membrane protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins.

列出全部抗体 基因 基因ID UniProt
GIMAP3 83408 Q99MI6
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通过反应活性、应用领域、克隆类型和共轭标记 GIMAP3 抗体

特性 应用范围 宿主 克隆类型
Mouse (Murine)


更多抗GTPase IMAP Family Member 3的相互作用对抗体

Mouse (Murine) GTPase IMAP Family Member 3 (GIMAP3) interaction partners

  1. quantitative changes in expression of Gimap3 and the paralogue Gimap5 affect mtDNA segregation in hematopoietic tissues. Gimap3 localizes to the endoplasmic reticulum and not mitochondria.

  2. The defects in T-cell cellularity were more severe in mice lacking both Gimap3 and Gimap5.

  3. Data shsow that Gimap3 is important for T cell development and survival, suggesting that leukocyte survival may be a key factor in the genetic regulation of mtDNA sequence variants and in modulating human mitochondrial diseases.

GTPase IMAP Family Member 3 (GIMAP3) 抗原简介

蛋白简介

This gene encodes a mitochondrial membrane protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. The expression of this gene is induced in BCR\\/ABL-expressing cells. The encoded protein lacks an N-terminal mitochondrial signal sequence. Experimental studies showed that mitochondrial localization relies on the C-terminal transmembrane domain. In humans, the IAN subfamily genes are located in a cluster at 7q36.1

Gene names and symbols associated with GIMAP3

  • GTPase, IMAP family member 3 (Gimap3) 抗体
  • 2010110D23Rik 抗体
  • Gimap5 抗体
  • Ian4 抗体

Protein level used designations for GIMAP3

GTPase IMAP family member 3 , IAN-4 , immune associated nucleotide 4 , immunity-associated nucleotide 4 protein

GENE ID SPECIES
83408 Mus musculus
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