anti-GTP Cyclohydrolase I Feedback Regulator (GCHFR) 抗体

GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. 再加上,我们可以发GCHFR 蛋白 (8)GCHFR 试剂盒 (4)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
GCHFR 2644 P30047
GCHFR 320415 P99025
GCHFR 171128 P70552

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Showing 10 out of 57 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB 100 μL Log in to see 24至29个工作日
¥3,074.65
详细
非结合性 IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using GCHFR Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 24至29个工作日
¥3,026.87
详细
非结合性 WB GCHFR Antibody (C-term)  western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the GCHFR antibody detected the GCHFR protein (arrow). 400 μL Log in to see 5至8个工作日
¥2,325.14
详细
非结合性 WB 50 μg Log in to see 29至35个工作日
¥5,538.93
详细
非结合性 WB Western Blot analysis of GCHFR expression in transfected 293T cell line by GCHFR MaxPab polyclonal antibody.Lane 1: GCHFR transfected lysate(9.70 KDa).Lane 2: Non-transfected lysate. 100 μg Log in to see 29至34个工作日
¥3,073.67
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非结合性 ELISA, WB 50 μg Log in to see 24至29个工作日
¥4,312.06
详细
非结合性 IHC (p), ELISA 100 μL Log in to see 29至35个工作日
¥4,852.60
详细
Alexa Fluor 350 IF (p)   100 μL Log in to see 14至17个工作日
¥3,555.98
详细
Alexa Fluor 488 IF (p)   100 μL Log in to see 14至17个工作日
¥3,555.98
详细
Alexa Fluor 555 IF (p)   100 μL Log in to see 14至17个工作日
¥3,555.98
详细

通过反应活性、应用领域、克隆类型和共轭标记 GCHFR 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-GCHFR 抗体

  1. Cow (Bovine) Polyclonal GCHFR Primary Antibody for WB - ABIN2781329 : Ohta, Funayama, Ichinose, Toyoshima, Urano, Matsuo, Tomoko, Yukihiko, Yoshino, Yokoyama, Shimazu, Maeda, Hasegawa, Obata: Novel mutations in the guanosine triphosphate cyclohydrolase 1 gene associated with DYT5 dystonia. in Archives of neurology 2006 (PubMed)

  2. Human Polyclonal GCHFR Primary Antibody for WB - ABIN515984 : Du, Teng, Lawrence, Guan, Xu, Ge, Shi: The protein partners of GTP cyclohydrolase I in rat organs. in PLoS ONE 2012 (PubMed)

  3. Human Polyclonal GCHFR Primary Antibody for IHC, ELISA - ABIN1534956 : Hochstrasser, Frutiger, Paquet, Bairoch, Ravier, Pasquali, Sanchez, Tissot, Bjellqvist, Vargas: Human liver protein map: a reference database established by microsequencing and gel comparison. in Electrophoresis 1993 (PubMed)

更多抗GCHFR的相互作用对抗体

Human GTP Cyclohydrolase I Feedback Regulator (GCHFR) interaction partners

  1. homozygous individuals for the TT haplotype were less likely to respond to the SSRI fluoxetine than to the nortriptyline suggesting a biological process through which GCHFR promoter variants might influence antidepressant response.

  2. Studies provide a new mechanism for regulation of endothelial GTPCH-1 (显示 GCH1 抗体) by its phosphorylation and interplay with GFRP.

  3. Bacterial lipopolysaccharide down-regulates expression of GTP cyclohydrolase I feedback regulatory protein

  4. allosteric regulation of GTPCH-I activity in the cardiovascular system maybe an important mechanism regulating BH4 levels through GTPCH-I feedback regulatory protein signaling

  5. GFRP/GTPCHI (显示 GCH1 抗体) axis functions in epidermal keratinocytes and melanocytes in the cytosol and nucleus.

  6. GCH1 (显示 GCH1 抗体) mutations in Japanese patients with DYT5 (显示 GCH1 抗体) dystonia. In some of them, the GCH1 (显示 GCH1 抗体) enzyme activity was proved to be impaired.

  7. The co-expression of GTP cyclohydrolase I (显示 GCH1 抗体) (GCHI) with tyrosine hydroxylase (TH (显示 TH 抗体)) indicates that TH is indeed active in human neurosecretory neurons.

  8. Demonstrate role for GFRP in regulating iNOS (显示 NOS2 抗体)-mediated NO synthesis and suggest that the allosteric regulation of GTP (显示 AK3 抗体)-CH1 activity by GFRP may be an important mechanism regulating BH(4) and NO levels in vivo.

  9. 6BH(4) de novo synthesis is controlled by H(2)O(2) in a concentration-dependent manner, but H(2)O(2)-mediated oxidation does not affect the functionality of the GTPCHI (显示 GCH1 抗体)/GFRP complex.

Mouse (Murine) GTP Cyclohydrolase I Feedback Regulator (GCHFR) interaction partners

  1. Studies provide a new mechanism for regulation of endothelial GTPCH-1 (显示 GCH1 抗体) by its phosphorylation and interplay with GFRP (显示 NR4A1 抗体).

  2. GTPCH (显示 GCH1 抗体) expression is the primary regulator of BH4 levels, and changes in GTPCH (显示 GCH1 抗体) or BH4 are not necessarily accompanied by changes in GFRP (显示 NR4A1 抗体) expression.

GCHFR 抗原简介

蛋白简介

GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide.

Gene names and symbols associated with GCHFR

  • GTP cyclohydrolase I feedback regulator (LOC100220034) 抗体
  • GTP cyclohydrolase I feedback regulator (GCHFR) 抗体
  • GTP cyclohydrolase I feedback regulator (Gchfr) 抗体
  • 2010323F13Rik 抗体
  • GFRP 抗体
  • HsT16933 抗体
  • P35 抗体

Protein level used designations for GCHFR

GTP cyclohydrolase I feedback regulator , GTP cyclohydrolase 1 feedback regulatory protein , GTP cyclohydrolase I feedback regulatory protein , GFRP , p35

GENE ID SPECIES
100220034 Taeniopygia guttata
2644 Homo sapiens
617650 Bos taurus
320415 Mus musculus
171128 Rattus norvegicus
423003 Gallus gallus
100153745 Sus scrofa
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