GTP Binding Protein 3 (Mitochondrial) (GTPBP3) ELISA试剂盒

This locus encodes a GTP-binding protein. 再加上,我们可以发GTPBP3 抗体 (33)GTPBP3 蛋白 (5)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
GTPBP3 290633 Q5PQQ1
GTPBP3 70359 Q923K4
GTPBP3 84705 Q969Y2

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Mouse (Murine) GTP Binding Protein 3 (Mitochondrial) (GTPBP3) interaction partners

  1. These observations suggest that the mouse Gtpbp3 is an evolutionarily conserved mitochondrial GTP-binding protein involved in the tRNA modification.

Human GTP Binding Protein 3 (Mitochondrial) (GTPBP3) interaction partners

  1. GTPBP3 defective expression is associated with an mitochondrial-tRNA hypomodification status.GTPBP3 plays a role in the regulation of UCP2 (显示 UCP2 ELISA试剂盒) and MCP1 (显示 CCL2 ELISA试剂盒) proteins through AMPK (显示 PRKAA1 ELISA试剂盒) signaling.

  2. Results show that post-transcriptional expression of GTPBP3, MTO1 and TRMU (显示 TRMU ELISA试剂盒) genes is down-regulated, leading to mt-tRNA hypomodification and contributing to mitochondrial dysfunction in MELAS cybrids.

  3. Most individuals with GTPBP3 mutations developed neurological symptoms and MRI (显示 C7ORF49 ELISA试剂盒) involvement of thalamus, putamen, and brainstem resembling Leigh syndrome.

  4. GTPBP3 localizes in the mitochondria and is a deafness-associated homolog of yeast MSS1.

  5. Phenotype of non-syndromic deafness associated with the mitochondrial A1555G mutation is modulated by mitochondrial RNA modifying enzymes MTO1 and GTPBP3.

  6. Data show that the two most abundant GTPBP3 isoforms exhibit moderate affinity for guanine nucleotides like their bacterial homologue, MnmE, although they hydrolyze GTP (显示 AK3 ELISA试剂盒) at a 100-fold lower rate.

GTPBP3 抗原简介

Antigen Summary

This locus encodes a GTP-binding protein. The encoded protein is localized to the mitochondria and may play a role in mitochondrial tRNA modification. Polymorphisms at this locus may be associated with severity of aminoglycoside-induced deafness, a disease associated with a mutation in the 12S rRNA. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene names and symbols associated with GTPBP3

  • GTP binding protein 3 (mitochondrial) (GTPBP3) 抗体
  • GTP binding protein 3 (Gtpbp3) 抗体
  • GTP binding protein 3 (gtpbp3) 抗体
  • 2410009F13Rik 抗体
  • AI607903 抗体
  • GTPBG3 抗体
  • GTPBP3 抗体
  • MSS1 抗体
  • MTGP1 抗体
  • THDF1 抗体
  • zgc:112394 抗体

Protein level used designations for GTPBP3

GTP binding protein 3 (mitochondrial) , tRNA modification GTPase GTPBP3, mitochondrial , tRNA modification GTPase GTPBP3, mitochondrial-like , GTP-binding protein 3 , mitochondrial GTP-binding protein 1

GENE ID SPECIES
484838 Canis lupus familiaris
539656 Bos taurus
100070158 Equus caballus
100392904 Callithrix jacchus
100474937 Ailuropoda melanoleuca
290633 Rattus norvegicus
553807 Danio rerio
70359 Mus musculus
84705 Homo sapiens
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