电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

FANCD2 抗体

(Fanconi Anemia, Complementation Group D2 (FANCD2))
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity\; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
FANCD2 抗体  (N-Term) FANCD2 抗体  (N-Term) FANCD2 抗体 (N-Term) (ABIN540721)

FANCD2 适用: 人 WB, IHC, IF, IHC (p), IP 宿主: 兔 Polyclonal unconjugated

FANCD2 抗体  (N-Term) FANCD2 抗体  (N-Term) FANCD2 抗体 (N-Term) (ABIN363390)

FANCD2 适用: 人, 小鼠 WB, IHC, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated

FANCD2 抗体  (AA 1-230) FANCD2 抗体  (AA 1-230) FANCD2 抗体 (AA 1-230) (ABIN3022849)

FANCD2 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated

FANCD2 抗体 by Grade

Find FANCD2 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

FANCD2 抗体 by 适用

Find FANCD2 抗体 for a variety of species such as anti-Human FANCD2, anti-Mouse FANCD2, anti-Rat FANCD2. The species listed below are among those available. Click on a link to go to the corresponding products.

FANCD2 抗体 by 应用范围

Find FANCD2 抗体 validated for a specific application such as WB, IF (cc), IF (p), ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

FANCD2 抗体 by 抗体来源

Find FANCD2 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

FANCD2 抗体 by 抗原表位

Find FANCD2 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

FANCD2 抗体 by 克隆形成能力

Find available monoclonal or polyclonal FANCD2 抗体. Click on a link to go to the corresponding products.

FANCD2 抗体 by 克隆

Find FANCD2 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

FANCD2 抗体 by 标记

Find FANCD2 抗体 with a specific conjugate such as Biotin, Alexa Fluor 488, Alexa Fluor 555. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular FANCD2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF, IHC (p), IP
Validations
  • (5)
  • (4)
Cat. No. ABIN540721
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, IF, IP, ICC
Validations
  • (6)
Cat. No. ABIN363390
Quantity 0.05 mL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IP
Validations
  • (4)
Cat. No. ABIN3022849
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (3)
Cat. No. ABIN6261674
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (3)
Cat. No. ABIN6255106
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
  • (2)
Cat. No. ABIN540832
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7152548
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IF
Validations
  • (2)
Cat. No. ABIN7260125
Quantity 200 μL
Datasheet Datasheet
Reactivity
Application WB, IP, ChIP
Validations
  • (4)
  • (1)
Cat. No. ABIN534121
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN7267126
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (1)
Cat. No. ABIN682918
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6243659
Quantity 80 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN7009743
Quantity 60 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7138489
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA
Validations
  • (1)
Cat. No. ABIN3184593
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our FANCD2 抗体

Ramanagoudr-Bhojappa, Carrington, Ramaswami, Bishop, Robbins, Jones, Harper, Frederickson, Kimble, Sood, Chandrasekharappa: "Multiplexed CRISPR/Cas9-mediated knockout of 19 Fanconi anemia pathway genes in zebrafish revealed their roles in growth, sexual development and fertility." in: PLoS genetics, Vol. 14, Issue 12, pp. e1007821, (2019) (PubMed).

Balcerek, Jiang, Li, Jiang, Holdreith, Singh, Chandra, Lv, Ren, Rozenova, Li, Greenberg, Tong: "Lnk/Sh2b3 deficiency restores hematopoietic stem cell function and genome integrity in Fancd2 deficient Fanconi anemia." in: Nature communications, Vol. 9, Issue 1, pp. 3915, (2019) (PubMed).

Andreev, Hristova, Asparuhova, Danovski, Stoynov, Gospodinov: "Mammalian INO80 chromatin remodeler cooperates with FANCM to mediate DNA interstrand crosslink-induced checkpoint activation and repair." in: DNA repair, Vol. 74, pp. 38-50, (2019) (PubMed).

Pladevall-Morera, Munk, Ingham, Garribba, Albers, Liu, Olsen, Lopez-Contreras: "Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability." in: Nucleic acids research, (2019) (PubMed).

Tacconi, Badie, De Gregoriis, Reisländer, Lai, Porru, Folio, Moore, Kopp, Baguña Torres, Sneddon, Green, Dedic, Lee, Batra, Rueda, Bruna, Leonetti, Caldas, Cornelissen, Brino, Ryan, Biroccio et al.: "Chlorambucil targets BRCA1/2-deficient tumours and counteracts PARP inhibitor resistance. ..." in: EMBO molecular medicine, (2019) (PubMed).

Huang, Zhang, Bellani, Pokharel, Gichimu, James, Gali, Ling, Yan, Xu, Chen, Meetei, Li, Wang, Seidman: "Remodeling of Interstrand Crosslink Proximal Replisomes Is Dependent on ATR, FANCM, and FANCD2." in: Cell reports, Vol. 27, Issue 6, pp. 1794-1808.e5, (2019) (PubMed).

Fragkos, Barra, Egger, Bordignon, Lemacon, Naim, Coquelle: "Dicer prevents genome instability in response to replication stress." in: Oncotarget, Vol. 10, Issue 43, pp. 4407-4423, (2019) (PubMed).

Porro, Berti, Pizzolato, Bologna, Kaden, Saxer, Ma, Nagasawa, Sartori, Jiricny: "FAN1 interaction with ubiquitylated PCNA alleviates replication stress and preserves genomic integrity independently of BRCA2." in: Nature communications, Vol. 8, Issue 1, pp. 1073, (2018) (PubMed).

Tremblay, Huang, Lévesque, Carreau: "Fanconi anemia core complex-dependent HES1 mono-ubiquitination regulates its transcriptional activity." in: BMC research notes, Vol. 11, Issue 1, pp. 138, (2018) (PubMed).

Higgs, Sato, Reynolds, Begum, Bayley, Goula, Vernet, Paquin, Skalnik, Kobayashi, Takata, Howlett, Kurumizaka, Kimura, Stewart: "Histone Methylation by SETD1A Protects Nascent DNA through the Nucleosome Chaperone Activity of FANCD2." in: Molecular cell, Vol. 71, Issue 1, pp. 25-41.e6, (2018) (PubMed).

Aliases for FANCD2 抗体

Fanconi anemia complementation group D2 (FANCD2) 抗体
CG17269 gene product from transcript CG17269-RA (Fancd2) 抗体
Fanconi anemia group D2 protein (LOC100455970) 抗体
Fanconi anemia complementation group D2 (fancd2) 抗体
Fanconi anemia, complementation group D2 (fancd2) 抗体
Fanconi anemia complementation group D2 L homeolog (fancd2.L) 抗体
Fanconi anemia, complementation group D2 (FANCD2) 抗体
Fanconi anemia, complementation group D2 (Fancd2) 抗体
2410150O07Rik 抗体
AU015151 抗体
BB137857 抗体
CG17269 抗体
CG31192 抗体
CG31194 抗体
Dmel\\CG17269 抗体
dmFANCD2 抗体
FA-D2 抗体
FA4 抗体
FACD 抗体
FAD 抗体
FAD2 抗体
FANCD 抗体
FANCD2 抗体
xfancd2 抗体
You are here:
客服