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anti-FK506 Binding Protein 8, 38kDa (FKBP8) 抗体

The protein encoded by FKBP8 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. 再加上,我们可以发FK506 Binding Protein 8, 38kDa 蛋白 (7)FK506 Binding Protein 8, 38kDa 试剂盒 (5)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
FKBP8 14232 O35465
FKBP8 290652 Q3B7U9
FKBP8 23770 Q14318

antibodies-online.cn销售最多的anti-FK506 Binding Protein 8, 38kDa 抗体

Showing 10 out of 113 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-FKBP8 Antibody Titration: 0.2-1 ug/mlPositive Control: Hela cell lysate 100 μL Log in to see 24至29个工作日
¥3,074.65
详细
非结合性 EIA, WB 0.1 mg Log in to see 29至35个工作日
¥3,632.23
详细
Cow 非结合性 WB   100 μL Log in to see 24至29个工作日
¥3,074.65
详细
非结合性 WB FKBP8 Antibody (Center) (ABIN652170) western blot analysis in CEM cell line lysates (35 µg/lane). This demonstrates the FKBP8 antibody detected the FKBP8 protein (arrow). 400 μL Log in to see 9至13个工作日
¥2,325.14
详细
非结合性 ELISA, WB Western blot using protein A purified anti-FKBP8 antibody shows detection of exogenous FKBP8 in 50 µg of HEK293T whole cell lysate (lane 1). The results of peptide competition are shown in lane 2 where no specific staining is noted after the antibody is first incubated for 1h with the immunizing peptide in 5% BLOTTO prior to reaction with the membrane. The membrane was probed with the primary antibody at a 1:1,000 dilution in 5% BLOTTO at 4° C, overnight. 25 μL Log in to see 23至28个工作日
¥3,357.01
详细
Bat 非结合性 WB 50 μg Log in to see 29至35个工作日
¥5,538.93
详细
Bat 非结合性 WB 50 μg Log in to see 29至35个工作日
¥5,538.93
详细
非结合性 WB Western blot analysis of FKBP-38 with mouse intestine tissue lysate (left lane) and Jurkat cell lysate (Right lane). 100 μg Log in to see 24至29个工作日
¥3,240.37
详细
非结合性 WB 0.1 mg Log in to see 29至35个工作日
¥3,632.23
详细
非结合性 ELISA, WB Western blot using protein A purified anti-FKBP8 antibody shows detection of exogenous FKBP8 in 50 µg of HEK293T whole cell lysate (lane 1). The results of peptide competition are shown in lane 2 where no specific staining is noted after the antibody is first incubated for 1h with the immunizing peptide in 5% BLOTTO prior to reaction with the membrane. The membrane was probed with the primary antibody at a 1:1,000 dilution in 5% BLOTTO at 4° C, overnight. 100 μg Log in to see 23至28个工作日
¥9,424.48
详细

通过反应活性、应用领域、克隆类型和共轭标记 FKBP8 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-FK506 Binding Protein 8, 38kDa 抗体

  1. Cow (Bovine) Polyclonal FKBP8 Primary Antibody for WB - ABIN2782773 : Okamoto, Omori, Kaname, Abe, Nishimura, Suzuki, Miyamura, Yoshimori, Moriishi, Matsuura: A single-amino-acid mutation in hepatitis C virus NS5A disrupting FKBP8 interaction impairs viral replication. in Journal of virology 2008 (PubMed)

  2. Human Polyclonal FKBP8 Primary Antibody for EIA, WB - ABIN401051 : Portier, Taglialatela: Bcl-2 localized at the nuclear compartment induces apoptosis after transient overexpression. in The Journal of biological chemistry 2006 (PubMed)

更多抗FK506 Binding Protein 8, 38kDa的相互作用对抗体

Mouse (Murine) FK506 Binding Protein 8, 38kDa (FKBP8) interaction partners

  1. Our findings thus indicate that the FKBP38-ANKMY2 (显示 ANKMY2 抗体) axis plays a key role in regulation of Shh (显示 SHH 抗体) signaling in vivo.

  2. In pre-hearing time Fkbp8-specific signal was also observed in the tectorial membrane, whose alpha- and beta-Tectorin (显示 TECTB 抗体) components show similar time-dependent expression of mRNA as Fkbp8.

  3. used systemic gene transfer in tumor-bearing mice to identify novel antiinvasive and antimetastatic functions for Fkbp8, and subsequently for Fkbp1a (显示 FKBP1A 抗体).

  4. Results show that FKBP8 is an essential antagonist of sonic hedgehog (显示 SHH 抗体) signaling in central nervous system development.

  5. FKBP38 functions to anchor the 26S proteasome (显示 Psmd4 抗体) at the organellar membrane

  6. Gene expression analysis of Fkbp8 mutants revealed a perturbation of expression of neural tube patterning genes, suggesting that endogenous FKBP8 activity establishes dorso-ventral patterning of the neural tube.

  7. Findings suggest that FKBP38 is required for neuroectodermal organization during neural tube formation as a result of its anti-apoptotic activity and regulation of neurite extension

  8. Disruption of FKBP8 function activates the Shh (显示 SHH 抗体) signaling pathway cell-autonomously dependent on the Gli2 (显示 GLI2 抗体) transcription factor and kinesin-2 (显示 KIF2A 抗体) subunit Kif3a (显示 KIF3A 抗体), a component of the intraflagellar transport machinery used to generate cilia.

  9. Data indicate that PHD2 (显示 EGLN1 抗体) protein stability is regulated by a ubiquitin-independent proteasomal pathway involving FKBP38 as adaptor protein that mediates proteasomal interaction.

Human FK506 Binding Protein 8, 38kDa (FKBP8) interaction partners

  1. The information presented here provides important clues for understanding the catalytic activity of FKBP38, its regulation by the unique N-terminal extension, and the potential calcium- and calmodulin (显示 CALM1 抗体)-mediated activation of FKBP38.

  2. Overexpression of permanently active S100P (显示 S100P 抗体) in Huh-7 cells inhibited the interaction of FKBP38 with Bcl-2 (显示 BCL2 抗体), resulting in the suppression of Bcl-2 (显示 BCL2 抗体) stability

  3. FK506 binding protein 8 peptidylprolyl isomerase activity manages a late stage of cystic fibrosis transmembrane conductance regulator (CFTR (显示 CFTR 抗体)) folding and stability

  4. The derived structure model of the complex between Bcl-2 (显示 BCL2 抗体) and the FKBP38 catalytic domain features both electrostatic and hydrophobic intermolecular contacts and provides a rationale for the regulation of the FKBP38/Bcl-2 (显示 BCL2 抗体) interaction by Ca(2 (显示 CA2 抗体)+).

  5. Data support a dual role for FKBP38 in regulating CFTR (显示 CFTR 抗体) synthesis and post-translational folding.

  6. a dual mechanism for PA activation of mTORC1: PA displaces FKBP38 from mTOR (显示 FRAP1 抗体) and allosterically stimulates the catalytic activity of mTORC1.

  7. this charge-sensitive site in the FKBP (显示 FKBP7 抗体) domain participates in the regulation of FKBP38 function by enabling electrostatic interactions with ligand proteins and/or salt ions such as Ca(2 (显示 CA2 抗体)+)

  8. These results demonstrate that FKBP38 is a novel regulator of the oncogenic protein PRL-3 abundance and that alteration in the stability of PRL-3 can have a dramatic impact on cell proliferation.

  9. novel insights into the structural arrangement of FKBP38/calmodulin (显示 CALM1 抗体) complex

  10. FKBP38 is a key player in regulating the function of Bcl-2 (显示 BCL2 抗体) by antagonizing caspase (显示 CASP3 抗体)-dependent degradation through the direct interaction with the flexible loop domain of Bcl-2 (显示 BCL2 抗体), which contains the caspase (显示 CASP3 抗体) cleavage site

FK506 Binding Protein 8, 38kDa (FKBP8) 抗原简介

蛋白简介

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. Unlike the other members of the family, this encoded protein does not seem to have PPIase/rotamase activity. It may have a role in neurons associated with memory function.

Gene names and symbols associated with FKBP8

  • FK506 binding protein 8, 38kDa (FKBP8) 抗体
  • FK506 binding protein 8, 38kDa (fkbp8) 抗体
  • FK506-binding protein 8 (fkbp8) 抗体
  • FK506 binding protein 8 (Fkbp8) 抗体
  • FK506 binding protein 8 (fkbp8) 抗体
  • 38kDa 抗体
  • FKBP-8 抗体
  • FKBP-38 抗体
  • fkbp8 抗体
  • FKBP38 抗体
  • FKBPr38 抗体
  • zgc:77672 抗体

Protein level used designations for FKBP8

peptidyl-prolyl cis-trans isomerase FKBP8 , FK506 binding protein 8, 38kDa , peptidyl-prolyl cis-trans isomerase FKBP8-like , FK506-binding protein 8 , 38 kDa FK506-binding protein , 38 kDa FKBP , FK506-binding protein 38 , FKBPR38 , PPIase FKBP8 , mFKBP38 , rotamase , FK506-binding protein 8 (38kD) , FKBP-38 , FKBP-8 , hFKBP38

GENE ID SPECIES
420123 Gallus gallus
455862 Pan troglodytes
100145724 Xenopus (Silurana) tropicalis
100443356 Pongo abelii
100194916 Salmo salar
14232 Mus musculus
290652 Rattus norvegicus
393858 Danio rerio
23770 Homo sapiens
484819 Canis lupus familiaris
512356 Bos taurus
495188 Xenopus laevis
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