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FBXL19 encodes a member of the Skp1-Cullin-F-box family of E3 ubiquitin ligases. 再加上，我们可以发FBXL19 试剂盒 (12) 和 FBXL19 蛋白 (3)和数多这个蛋白质的别的产品。
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Human Polyclonal FBXL19 Primary Antibody for WB - ABIN1537454
Wei, Mialki, Dong, Khoo, Mallampalli, Zhao, Zhao: A new mechanism of RhoA ubiquitination and degradation: Roles of SCF(FBXL19) E3 ligase and Erk2. in Biochimica et biophysica acta 2013
Show all 3 Pubmed References
Collectively these data unveil that FBXL19 functions as an antagonist of Rac3 (显示 RAC3 抗体) by regulating its stability and regulates the TGFbeta1 (显示 TGFB1 抗体)-induced E-cadherin (显示 CDH1 抗体) down-regulation.
The results demonstrate that Fbxl19 recruitment to CpG islands is required for Rnf20-mediated H2B monoubiquitination.
SCF (显示 KITLG 抗体)(FBXL19) targets RhoA (显示 RHOA 抗体) for its disposal, a process regulated by Erk2 (显示 MAPK1 抗体).
Data indicate that overexpression of FBXL19 decreased both Rac1 active and inactive forms and significantly reduced cellular migration.
The fundamental observation was that FBXL19 attenuated IL-33 (显示 IL33 抗体)-mediated activity by removing ST2L (显示 TMED1 抗体), but not sST2 (显示 SSTR2 抗体) or IL-1R1, on the cell surface.
This gene encodes a member of the Skp1-Cullin-F-box family of E3 ubiquitin ligases. The encoded protein binds to the transmembrane receptor ST2L and regulates its ubiquination and degradation. This protein has been linked to the regulation of pulmonary inflammation and psoriasis. Alternative splicing results in multiple transcript variants.
F-box/LRR-repeat protein 19
, F-box and leucine-rich repeat protein 19
, f-box/LRR-repeat protein 19-like
, jumonji C domain-containing histone demethylase 1C