EGLN1 抗体
(Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1))
The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3). [provided by RefSeq, Nov 2009].
recommended
recommended
KO Validated EGLN1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
recommended
EGLN1 抗体 by Grade
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EGLN1 抗体 by 适用
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EGLN1 抗体 by 克隆形成能力
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Popular EGLN1 抗体
Product
Reactivity
Application
Validations
Cat. No.
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Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC
Validations
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Cat. No.
ABIN3021560
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IHC, IF
Validations
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Cat. No.
ABIN7266909
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC
Validations
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Cat. No.
ABIN7255273
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IF, IP, ICC
Validations
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Cat. No.
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Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, FACS
Validations
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Cat. No.
ABIN5577118
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (2)
Cat. No.
ABIN702640
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IHC, ELISA
Validations
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Cat. No.
ABIN7151443
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA
Validations
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- (1)
Cat. No.
ABIN565755
Quantity
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Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (2)
Cat. No.
ABIN6261464
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IHC, IP
Validations
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- (1)
Cat. No.
ABIN540735
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF, IC
Validations
- (3)
Cat. No.
ABIN7305930
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC, ELISA
Validations
- (1)
Cat. No.
ABIN7151442
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, StM
Validations
- (1)
Cat. No.
ABIN6940360
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Chicken, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN202496
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF, IF (cc), IHC (p)
Validations
Cat. No.
ABIN6989779
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our EGLN1 抗体
: "Loss of Phd2 cooperates with BRAFV600E to drive melanomagenesis. ..." in: Nature communications, Vol. 9, Issue 1, pp. 5426, (2019) (PubMed).: "Inducing cancer indolence by targeting mitochondrial Complex I is potentiated by blocking macrophage-mediated adaptive responses. ..." in: Nature communications, Vol. 10, Issue 1, pp. 903, (2019) (PubMed).
: "Metallothionein 3 Controls the Phenotype and Metabolic Programming of Alternatively Activated Macrophages." in: Cell reports, Vol. 27, Issue 13, pp. 3873-3886.e7, (2019) (PubMed).
: "A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension." in: Nature communications, Vol. 10, Issue 1, pp. 2130, (2019) (PubMed).
: "Systemic silencing of PHD2 causes reversible immune regulatory dysfunction. ..." in: The Journal of clinical investigation, Vol. 130, pp. 3640-3656, (2019) (PubMed).
: "The Factor Inhibiting HIF Asparaginyl Hydroxylase Regulates Oxidative Metabolism and Accelerates Metabolic Adaptation to Hypoxia." in: Cell metabolism, Vol. 27, Issue 4, pp. 898-913.e7, (2018) (PubMed).
: "Intermittent hypoxia induces beneficial cardiovascular remodeling in left ventricular function of type 1 diabetic rat." in: Anatolian journal of cardiology, Vol. 19, Issue 4, pp. 259-266, (2018) (PubMed).
: "Redox regulation of EGFR steers migration of hypoxic mammary cells towards oxygen." in: Nature communications, Vol. 9, Issue 1, pp. 4545, (2018) (PubMed).
: "The vacuolar-ATPase complex and assembly factors, TMEM199 and CCDC115, control HIF1α prolyl hydroxylation by regulating cellular iron levels." in: eLife, Vol. 6, (2017) (PubMed).
: "Ablation of endothelial prolyl hydroxylase domain protein-2 promotes renal vascular remodelling and fibrosis in mice." in: Journal of cellular and molecular medicine, (2017) (PubMed).
Aliases for EGLN1 抗体
egl nine homolog 1 (C. elegans) (EGLN1) 抗体egl-9 family hypoxia inducible factor 1 (EGLN1) 抗体
egl-9 family hypoxia-inducible factor 1 S homeolog (egln1.S) 抗体
egl-9 family hypoxia-inducible factor 1b (egln1b) 抗体
egl-9 family hypoxia-inducible factor 1 (Egln1) 抗体
AI503754 抗体
C1orf12 抗体
ECYT3 抗体
EGLN1 抗体
egln2 抗体
Hif-p4h-2 抗体
HIF-PH2 抗体
HIFPH2 抗体
HPH-2 抗体
HPH2 抗体
ORF13 抗体
PHD-2 抗体
phd2 抗体
Phd2 抗体
PHD2 抗体
SM-20 抗体
SM20 抗体
zgc:92314 抗体
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