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Dystrophin 抗体

(Dystrophin (DMD))
The dystrophin gene is the largest gene found in nature, measuring 2.4 Mb. The gene was identified through a positional cloning approach, targeted at the isolation of the gene responsible for Duchenne (DMD) and Becker (BMD) Muscular Dystrophies. DMD is a recessive, fatal, X-linked disorder occurring at a frequency of about 1 in 3,500 new-born males. BMD is a milder allelic form. In general, DMD patients carry mutations which cause premature translation termination (nonsense or frame shift mutations), while in BMD patients dystrophin is reduced either in molecular weight (derived from in-frame deletions) or in expression level. The dystrophin gene is highly complex, containing at least eight independent, tissue-specific promoters and two polyA-addition sites. Furthermore, dystrophin RNA is differentially spliced, producing a range of different transcripts, encoding a large set of protein isoforms. Dystrophin (as encoded by the Dp427 transcripts) is a large, rod-like cytoskeletal protein which is found at the inner surface of muscle fibers. Dystrophin is part of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton (F-actin) and the extra-cellular matrix. [provided by RefSeq, Jul 2008].
Dystrophin 抗体  (AA 346-635) Dystrophin 抗体  (AA 346-635) Dystrophin 抗体 (AA 346-635) (ABIN1679546)

DMD 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

Dystrophin 抗体 Dystrophin 抗体 Dystrophin 抗体 (ABIN7008615)

DMD 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

Dystrophin 抗体  (AA 1-635) Dystrophin 抗体  (AA 1-635) Dystrophin 抗体 (AA 1-635) (ABIN515027)

DMD 适用: 人 WB, IP, ELISA 宿主: 小鼠 Monoclonal 3A11 unconjugated

Dystrophin 抗体 by 适用

Find Dystrophin 抗体 for a variety of species such as anti-Human Dystrophin, anti-Mouse Dystrophin, anti-Rat Dystrophin. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find Dystrophin 抗体 validated for a specific application such as IHC, WB, ELISA, IP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

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Find Dystrophin 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

Dystrophin 抗体 by 克隆形成能力

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Find Dystrophin 抗体 with a specific conjugate such as Alexa Fluor 488, Alexa Fluor 555, Alexa Fluor 594. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular Dystrophin 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN1679546
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (4)
Cat. No. ABIN7008615
Quantity 60 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP, ELISA
Validations
  • (4)
Cat. No. ABIN515027
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA, Coat, StM
Validations
  • (4)
Cat. No. ABIN6939242
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC, IF
Validations
  • (4)
Cat. No. ABIN7266871
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (5)
Cat. No. ABIN3043317
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7433717
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA, Coat, StM
Validations
  • (3)
Cat. No. ABIN6939241
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA, Coat, StM
Validations
  • (3)
Cat. No. ABIN6939245
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7445825
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7150930
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7127460
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (1)
Cat. No. ABIN7433720
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (1)
Cat. No. ABIN7426295
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, ICC, IF
Validations
  • (1)
Cat. No. ABIN6261406
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our Dystrophin 抗体

Stay, Miterko, Arancillo, Lin, Sillitoe: "In vivo cerebellar circuit function is disrupted in an mdx mouse model of Duchenne muscular dystrophy." in: Disease models & mechanisms, Vol. 13, Issue 2, (2019) (PubMed).

Mondello, Cardia, Bartoloni, Asmundo, Ventura Spagnolo: "Immunohistochemical study on dystrophin expression in CAD-related sudden cardiac death: a marker of early myocardial ischaemia." in: International journal of legal medicine, Vol. 132, Issue 5, pp. 1333-1339, (2018) (PubMed).

Aoyama, Kawase, Bando, Monji, Murohara et al.: "Dipeptidyl Peptidase 4 Inhibition Alleviates Shortage of Circulating Glucagon-Like Peptide-1 in Heart Failure and Mitigates Myocardial Remodeling and Apoptosis via the Exchange Protein Directly ..." in: Circulation. Heart failure, Vol. 9, Issue 1, pp. e002081, (2016) (PubMed).

Annese, Corsi, Ruggieri, Tamma, Marinaccio, Picocci, Errede, Specchia, De Luca, Frassanito, Desantis, Vacca, Ribatti, Nico: "Isolation and characterization of neural stem cells from dystrophic mdx mouse." in: Experimental cell research, Vol. 343, Issue 2, pp. 190-207, (2016) (PubMed).

Puchert, Adams, Linke, Engele: "Evidence for the involvement of the CXCL12 system in the adaptation of skeletal muscles to physical exercise." in: Cellular signalling, Vol. 28, Issue 9, pp. 1205-15, (2016) (PubMed).

Kawase, Bando, Nishimura, Aoyama, Monji, Murohara: "A dipeptidyl peptidase-4 inhibitor ameliorates hypertensive cardiac remodeling via angiotensin-II/sodium-proton pump exchanger-1 axis." in: Journal of molecular and cellular cardiology, Vol. 98, pp. 37-47, (2016) (PubMed).

Hosur, Kavirayani, Riefler, Carney, Lyons, Gott, Cox, Shultz: "Dystrophin and dysferlin double mutant mice: a novel model for rhabdomyosarcoma." in: Cancer genetics, Vol. 205, Issue 5, pp. 232-41, (2012) (PubMed).

Nguyen, Ginjaar, van Ommen, Morris: "Monoclonal antibodies for dystrophin analysis. Epitope mapping and improved binding to SDS-treated muscle sections." in: The Biochemical journal, Vol. 288 ( Pt 2), pp. 663-8, (1993) (PubMed).

Morris, Ellis, Nguyen: "A quantitative ELISA for dystrophin." in: Journal of immunological methods, Vol. 161, Issue 1, pp. 23-8, (1993) (PubMed).

Aliases for Dystrophin 抗体

dystrophin (DMD) 抗体
dystrophin (LOC708073) 抗体
dystrophin, gene 1 L homeolog (dmd.1.L) 抗体
dystrophin (LOC465557) 抗体
dystrophin, gene 1 (dmd.1) 抗体
dystrophin (dmd) 抗体
dystrophin, muscular dystrophy (Dmd) 抗体
dystrophin (Dmd) 抗体
Dystrophin (Dys) 抗体
BMD 抗体
cb664 抗体
CG7240 抗体
CG7243 抗体
CG7344 抗体
CG17750 抗体
CG31175 抗体
CG34157 抗体
CMD3B 抗体
det 抗体
DKFZp459C1629 抗体
DKFZp468A1620 抗体
DLP 抗体
DLP1 抗体
DLP2 抗体
DLP3 抗体
DLP186 抗体
DMD 抗体
Dmd 抗体
dmd 抗体
DmDLP 抗体
dmDLP 抗体
dmDp186 抗体
DmDYS 抗体
dmDys 抗体
Dmel\\CG34157 抗体
DNADMD1 抗体
Dp71 抗体
Dp117 抗体
Dp186 抗体
Dp205 抗体
Dp427 抗体
DXS142 抗体
DXS164 抗体
DXS206 抗体
DXS230 抗体
DXS239 抗体
DXS268 抗体
DXS269 抗体
DXS270 抗体
DXS272 抗体
DXSmh7 抗体
DXSmh9 抗体
dys 抗体
GI3046716 抗体
IDLP 抗体
im:6911785 抗体
mdx 抗体
MGC79631 抗体
MGC83347 抗体
pke 抗体
RATDMD 抗体
zfDYS 抗体
zgc:110165 抗体
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