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anti-Dual Specificity Phosphatase 1 (DUSP1) 抗体

The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. 再加上,我们可以发DUSP1 试剂盒 (27)DUSP1 蛋白 (5)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
DUSP1 1843 P28562
DUSP1 19252 P28563
DUSP1 114856 Q64623

antibodies-online.cn销售最多的anti-DUSP1 抗体

Showing 10 out of 109 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 山羊 非结合性 IHC (p), WB 0.1 mg Log in to see 29至35个工作日
¥3,632.23
详细
山羊 非结合性 IHC, ELISA, WB ABIN184638 (3.8µg/ml) staining of paraffin embedded Human Prostate. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. ABIN184638 (0.3µg/ml) staining of HeLa lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 24至29个工作日
¥9,230.97
详细
非结合性 IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human lung carcinoma, using MKP1 (Phospho-Ser359) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 24至29个工作日
¥3,026.87
详细
非结合性 EIA, WB 0.4 mL Log in to see 29至35个工作日
¥4,086.26
详细
非结合性 IHC, ELISA, WB Western blot analysis of extracts from Jurkat cells, using MKP1 (Ab-359) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using MKP1 (Ab-359) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 24至29个工作日
¥3,026.87
详细
非结合性 IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse lymphoma tissue labeled with Anti-DUSP1/MKP-1 Polyclonal Antibody, Unconjugated (ABIN735368) at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 5至7个工作日
¥2,709.56
详细
山羊 非结合性 EIA, IHC (p), WB 50 μg Log in to see 29至35个工作日
¥5,095.23
详细
非结合性 IF, WB The anti-DUSP1 Pab (ABIN392905) is used in Western blot to detect DUSP1 in 293 cell lysate. 400 μL Log in to see 5至8个工作日
¥2,325.14
详细
山羊 非结合性 IHC (p), IHC, ELISA, WB ABIN257653 staining (2µg/ml) of HeLa lysate (RIPA buffer, 35µg total protein per lane). Western Blot: MKP-1/DUSP1 Antibody [ABIN257653] - (0.3ug/ml) staining of HeLa lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 25至31个工作日
¥3,333.96
详细
Alexa Fluor 488 IF (p)   100 μL Log in to see 14至17个工作日
¥3,655.30
详细

通过反应活性、应用领域、克隆类型和共轭标记 DUSP1 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-DUSP1 抗体

  1. Human Polyclonal DUSP1 Primary Antibody for EIA, WB - ABIN360822 : Wu, Pew, Zou, Pang, Conzen: Glucocorticoid receptor-induced MAPK phosphatase-1 (MPK-1) expression inhibits paclitaxel-associated MAPK activation and contributes to breast cancer cell survival. in The Journal of biological chemistry 2005 (PubMed)
    Show all 5 references for ABIN360822

  2. Human Polyclonal DUSP1 Primary Antibody for IF (p), IHC (p) - ABIN735368 : Kato, Naiki-Ito, Naiki, Suzuki, Yamashita, Sato, Sagawa, Kato, Kuno, Takahashi: Connexin 32 dysfunction promotes ethanol-related hepatocarcinogenesis via activation of Dusp1-Erk axis. in Oncotarget 2016 (PubMed)
    Show all 2 references for ABIN735368

  3. Human Polyclonal DUSP1 Primary Antibody for IF (p) - ABIN894519 : Khadir, Tiss, Abubaker, Abufarha, Al-Khairi, Cherian, John, Kavalakatt, Warsame, Al-Madhoun, Al-Ghimlas, Elkum, Behbehani, Dermime, Dehbi: MAP kinase phosphatase DUSP1 is overexpressed in human obese and modulated by physical activity. in American journal of physiology. Endocrinology and metabolism 2014 (PubMed)

  4. Human Polyclonal DUSP1 Primary Antibody for IHC (p), IHC - ABIN257653 : Alessi, Smythe, Keyse: The human CL100 gene encodes a Tyr/Thr-protein phosphatase which potently and specifically inactivates MAP kinase and suppresses its activation by oncogenic ras in Xenopus oocyte extracts. in Oncogene 1993 (PubMed)

  5. Human Polyclonal DUSP1 Primary Antibody for IHC, ELISA - ABIN1532716 : Keyse, Emslie: Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase. in Nature 1992 (PubMed)

更多抗DUSP1的相互作用对抗体

Human Dual Specificity Phosphatase 1 (DUSP1) interaction partners

  1. Our results emphasize the importance of MKP-1 as a potential predictive biomarker for a subset of breast cancer patients with worse outcome and less susceptibility to treatment.

  2. Collectively, these data indicated that DUSP1 may induce the resistance against paclitaxel through the p38 MAPK (显示 MAPK14 抗体)-mediated overexpression of p-glycoprotein in human ovarian cancer cells.

  3. silencing of IL1B (显示 IL1B 抗体) plus dexamethasone-induced DUSP1 significantly reduced IRF1 (显示 IRF1 抗体) expression. IL1B (显示 IL1B 抗体)-induced expression of CXCL10 (显示 CXCL10 抗体) was largely insensitive to dexamethasone, whereas other DUSP1-enhanced, IRF1 (显示 IRF1 抗体)-dependent mRNAs showed various degrees of repression.

  4. dexamethasone-induced DUSP1 acts via p38 MAPK (显示 MAPK14 抗体) to switch on the mRNA destabilizing function of protein-tristetraprolin (显示 ZFP36 抗体) to repress pro-inflammatory cytokine secretion from ASM (显示 SMPD1 抗体) cells

  5. LPS (显示 IRF6 抗体) tolerance interferes with TLR4 (显示 TLR4 抗体) signaling by inhibiting Lyn (显示 LYN 抗体) and c-Src (显示 SRC 抗体) phosphorylation and their recruitment to TLR4 (显示 TLR4 抗体), while increasing the phosphatase activity and expression of PP2A (显示 PPP2R4 抗体), PTPN22 (显示 PTPN22 抗体), PTP1B (显示 PTPN1 抗体) and MKP1.

  6. This study shows that RIG-I (显示 DDX58 抗体) activation results in MKP-1-mediated inhibition of cell proliferation in melanoma cells via controlling the p38 (显示 CRK 抗体)-HSP27 (显示 HSPB1 抗体), c-Jun (显示 JUN 抗体) and rpS6 (显示 RPS6 抗体) pathways

  7. In E1a (显示 BCKDHA 抗体) expressing non-small cell lung carcinoma cells, upregulation of MKP1 and the subsequent p38MAPK (显示 MAPK14 抗体) inhibition is required for the induction of chemosensitivity to cisplatin.

  8. The heparin effects on TNFalpha (显示 TNF 抗体)-induced stress fiber formation and Map kinase (显示 MAPK1 抗体) signaling depend on increased DUSP1 expression.

  9. evidence of association between depressive symptom severity and increasing serum MKP-1 levels in women, and decreasing T levels in perimenopausal women.

  10. MKP-1 can attenuate tamoxifen-induced cell death through inhibiting the JNK (显示 MAPK8 抗体) signal pathway.

Mouse (Murine) Dual Specificity Phosphatase 1 (DUSP1) interaction partners

  1. PTHrP (显示 PTHLH 抗体) counteracts the pro-apoptotic actions of reactive oxygen species by a mechanism dependent on MKP1-induced dephosphorylation.

  2. A2AR (显示 ADORA2A 抗体) signaling regulates both basal and LPS (显示 TLR4 抗体)-induced DUSP1 levels in macrophages via activating the adenylate cyclase pathway.

  3. these data suggest an important role for DUSPs in regulating MAPK (显示 MAPK1 抗体) dephosphorylation, with an emphasis on DUSP1, during early adipogenesis

  4. Loss of DUSP1 does not cause changes in cartilage degeneration and gait in a mouse model of spontaneous osteoarthritis at 21 months of age.

  5. Nr4a1 (显示 NR4A1 抗体) induction is dependent on ERK1/2 (显示 MAPK1/3 抗体) and that MKP-1 negatively regulates this induction.

  6. MKP-1 negatively regulates chemokine (显示 CCL1 抗体)-driven osteoclast formation and subsequent bone resorption in response to LPS (显示 TLR4 抗体) stimulation

  7. results suggest that the p38alpha (显示 MAPK14 抗体)-MKP-1 signaling axis links IL-17R signaling in tissue-resident cells to autoimmune inflammation dependent on infiltrating T(H)17 cells.

  8. DUSP1 and tristetraprolin (显示 ZFP36 抗体) cooperate to regulate macrophage responses to lipopolysaccharide.

  9. MKP-1 regulated the expression of MMP-12 (显示 MMP12 抗体).

  10. CYLD (显示 CYLD 抗体) negatively regulates nontypeable Haemophilus influenzae-induced IL-8 (显示 IL8 抗体) expression via MKP-1-dependent inhibition of ERK (显示 EPHB2 抗体).

Cow (Bovine) Dual Specificity Phosphatase 1 (DUSP1) interaction partners

  1. MKP-1 is the specific phosphatase induced by AngII and involved in the negative feedback mechanism ensuring adequate ERK1/2 (显示 MAPK1/3 抗体)-mediated aldosterone production in response to the hormone.

Pig (Porcine) Dual Specificity Phosphatase 1 (DUSP1) interaction partners

  1. Agonist stimulation of vascular smooth muscle increases PKC (显示 FYN 抗体) activity, which, in turn, increases MKP-1 activity and maintains MAPK1 (显示 MAPK1 抗体) activity at submaximal values.

DUSP1 抗原简介

蛋白简介

The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes. Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation.

Gene names and symbols associated with DUSP1

  • dual specificity phosphatase 1 (DUSP1) 抗体
  • dual specificity phosphatase 1 (dusp1) 抗体
  • dual specificity phosphatase 1 (Dusp1) 抗体
  • 3CH134 抗体
  • cb269 抗体
  • CL100 抗体
  • DUSP1 抗体
  • erp 抗体
  • HVH1 抗体
  • id:ibd2586 抗体
  • mkp-1 抗体
  • Mkp1 抗体
  • PTPN10 抗体
  • Ptpn16 抗体
  • sb:cb269 抗体
  • U19515 抗体
  • wu:fd19g02 抗体
  • wu:fe50g09 抗体
  • zgc:55920 抗体

Protein level used designations for DUSP1

dual specificity protein phosphatase 1 , dual specificity phosphatase 1 , mkp-1 , MAP kinase phosphatase 1 , dual specificity protein phosphatase hVH1 , mitogen-activated protein kinase phosphatase 1 , protein-tyrosine phosphatase CL100 , serine/threonine specific protein phosphatase , mitogen-activated protein kinase phosphatase-1 , protein tyrosine phosphatase, non-receptor type 16 , protein-tyrosine phosphatase 3CH134 , protein-tyrosine phosphatase ERP , 3CH134/CL100 PTPase , MAP kinase phosphatase-1 , mitogen-activated protein (MAP) kinase phosphatase-1 , oxidative stress-inducible protein tyrosine phosphatase , protein tyrosine phosphatase non-receptor type 16 , protein-tyrosine phosphatase non-receptor type 16 , MAPK phosphatase 1

GENE ID SPECIES
374192 Gallus gallus
471742 Pan troglodytes
100219518 Taeniopygia guttata
100340993 Oryctolagus cuniculus
406340 Danio rerio
1843 Homo sapiens
19252 Mus musculus
114856 Rattus norvegicus
489117 Canis lupus familiaris
539175 Bos taurus
100522469 Sus scrofa
anti-DUSP1 (DUSP1) 抗体 精选生产商
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