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Doublecortin 抗体

(Doublecortin (DCX))
This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex, leading to epilepsy, mental retardation, subcortical band heterotopia ('double cortex' syndrome) in females and lissencephaly ('smooth brain' syndrome) in males. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010].
Doublecortin 抗体  (AA 362-411) Doublecortin 抗体  (AA 362-411) Doublecortin 抗体 (AA 362-411) (ABIN969513)

DCX 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 2G5 unconjugated

Doublecortin 抗体  (AA 232-242) Doublecortin 抗体  (AA 232-242) Doublecortin 抗体 (AA 232-242) (ABIN625829)

Verified DCX 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated

Doublecortin 抗体  (AA 362-411) Doublecortin 抗体  (AA 362-411) Doublecortin 抗体 (AA 362-411) (ABIN1844030)

DCX 适用: 人 WB, ELISA, IHC, FACS, IF/ICC 宿主: 小鼠 Monoclonal unconjugated

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Find Doublecortin 抗体 for a variety of species such as anti-Human Doublecortin, anti-Mouse Doublecortin, anti-Rat Doublecortin. The species listed below are among those available. Click on a link to go to the corresponding products.

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Popular Doublecortin 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, ICC, FACS
Validations
  • (1)
  • (7)
Cat. No. ABIN969513
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF
Validations
  • (5)
Cat. No. ABIN625829
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS, IF/ICC
Validations
  • (8)
Cat. No. ABIN1844030
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (1)
  • (3)
Cat. No. ABIN560579
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF, FACS
Validations
  • (4)
Cat. No. ABIN6391364
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7161378
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7248044
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN3021510
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IHC
Validations
  • (2)
Cat. No. ABIN7249670
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN3184352
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN6256273
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN7266839
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, ICC
Validations
  • (2)
Cat. No. ABIN2856489
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN6254069
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p), FACS
Validations
  • (3)
Cat. No. ABIN5533177
Quantity 400 μL
Datasheet Datasheet

Latest Publications for our Doublecortin 抗体

Zhang, Zhao, Zhang, Xu, Lian, Wu, He, Sun, Li: "Regulation of the p75 neurotrophin receptor attenuates neuroinflammation and stimulates hippocampal neurogenesis in experimental Streptococcus pneumoniae meningitis." in: Journal of neuroinflammation, Vol. 18, Issue 1, pp. 253, (2022) (PubMed).

Jiang, Brackeva, Stangé, Verhaeghen, Costa, Couillard-Després, Rotheneichner, Aigner, Van Schravendijk, Pipeleers, Ling, Gorus, Martens: "LC-MS/MS identification of doublecortin as abundant beta cell-selective protein discharged by damaged beta cells in vitro." in: Journal of proteomics, Vol. 80, pp. 268-80, (2013) (PubMed).

Klempin, Kronenberg, Cheung, Kettenmann, Kempermann: "Properties of doublecortin-(DCX)-expressing cells in the piriform cortex compared to the neurogenic dentate gyrus of adult mice." in: PLoS ONE, Vol. 6, Issue 10, pp. e25760, (2011) (PubMed).

Zhang, Du, Yang, Wang, Yu, Huang, Hu, Liu, Fu: "Granulocyte colony-stimulating factor increases the therapeutic efficacy of bone marrow mononuclear cell transplantation in cerebral ischemia in mice." in: BMC neuroscience, Vol. 12, pp. 61, (2011) (PubMed).

Evangelisti, Florian, Massimi, Dominici, Giannini, Galardi, Buè, Massalini, McDowell, Messi, Gulino, Farace, Ciafrè: "MiR-128 up-regulation inhibits Reelin and DCX expression and reduces neuroblastoma cell motility and invasiveness." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 23, Issue 12, pp. 4276-87, (2009) (PubMed).

Leger, Souville, Boddaert, Elie, Pinard, Plouin, Moutard, des Portes, Van Esch, Joriot, Renard, Chelly, Francis, Beldjord, Bahi-Buisson: "The location of DCX mutations predicts malformation severity in X-linked lissencephaly." in: Neurogenetics, Vol. 9, Issue 4, pp. 277-85, (2008) (PubMed).

Zhang, Ryan, Di Cesare, Liu, Walsh, You: "Doublecortin is expressed in articular chondrocytes." in: Biochemical and biophysical research communications, Vol. 363, Issue 3, pp. 694-700, (2007) (PubMed).

Magavi, Leavitt, Macklis: "Induction of neurogenesis in the neocortex of adult mice." in: Nature, Vol. 405, Issue 6789, pp. 951-5, (2000) (PubMed).

des Portes, Pinard, Billuart, Vinet, Koulakoff, Carrié, Gelot, Dupuis, Motte, Berwald-Netter, Catala, Kahn, Beldjord, Chelly: "A novel CNS gene required for neuronal migration and involved in X-linked subcortical laminar heterotopia and lissencephaly syndrome." in: Cell, Vol. 92, Issue 1, pp. 51-61, (1998) (PubMed).

Gleeson, Allen, Fox, Lamperti, Berkovic, Scheffer, Cooper, Dobyns, Minnerath, Ross, Walsh: "Doublecortin, a brain-specific gene mutated in human X-linked lissencephaly and double cortex syndrome, encodes a putative signaling protein." in: Cell, Vol. 92, Issue 1, pp. 63-72, (1998) (PubMed).

Aliases for Doublecortin 抗体

doublecortin (DCX) 抗体
doublecortin (Dcx) 抗体
18C15.5 抗体
DBCN 抗体
Dbct 抗体
DC 抗体
DCX 抗体
LISX 抗体
SCLH 抗体
XLIS 抗体
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