anti-Deoxyribonuclease II, Lysosomal (DNASE2) 抗体

The protein encoded by DNASE2 shares considerable sequence similarity to, and is structurally related to DNase II. 再加上,我们可以发Deoxyribonuclease II, Lysosomal 蛋白 (10)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
DNASE2 13423 P56542
DNASE2 1777 O00115
DNASE2 171575 Q9QZK8

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Showing 10 out of 53 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 IHC (p), WB 0.1 mg Log in to see 29至35个工作日
¥3,884.46
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非结合性 IHC (p), WB 0.1 mg Log in to see 26至31个工作日
¥3,105.26
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非结合性 IF (p), IHC (p) Formalin-fixed and paraffin embedded human laryngocarcinoma labeled with Anti-DNase II Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining. Formalin-fixed and paraffin embedded human laryngocarcinoma labeled with Anti-DNase II Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 5至7个工作日
¥2,610.23
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非结合性 ELISA, ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: DNase II Antibody [NBP1-76971] - Human spleen tissue with DNaseII antibody at 5 ug/ml. Western Blot: DNase II Antibody [NBP1-76971] - Analysis of Dnase II using NBP1-76971 at 2 ug/ml against 10 ug/lane of human spleen tissue lysate in the absence (lane 1) or presence (lane 2) of blocking peptide with DNase II at 1:500 dilution. 0.1 mg Log in to see 26至33个工作日
¥3,655.56
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非结合性 IHC (p), WB Human Thymus (formalin-fixed, paraffin-embedded) stained with DNASE2 antibody ABIN214485 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with DNASE2 antibody ABIN214485 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 29至35个工作日
¥4,324.07
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非结合性 IHC (p), WB 50 μg Log in to see 29至35个工作日
¥5,095.23
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Alexa Fluor 594 IF (p)   100 μL Log in to see 14至17个工作日
¥3,555.98
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Alexa Fluor 350 IF (p)   100 μL Log in to see 14至17个工作日
¥3,555.98
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Alexa Fluor 488 IF (p)   100 μL Log in to see 14至17个工作日
¥3,555.98
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Alexa Fluor 555 IF (p)   100 μL Log in to see 14至17个工作日
¥3,555.98
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通过反应活性、应用领域、克隆类型和共轭标记 DNASE2 抗体

特性 应用范围 宿主 克隆类型 标记
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Rat (Rattus) , ,


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引用最多的anti-Deoxyribonuclease II, Lysosomal 抗体

  1. Human Polyclonal DNASE2 Primary Antibody for IHC (p), WB - ABIN2473351 : Yasuda, Takeshita, Iida, Nakajima, Hosomi, Nakashima, Kishi: Molecular cloning of the cDNA encoding human deoxyribonuclease II. in The Journal of biological chemistry 1998 (PubMed)
    Show all 4 references for 2473351

  2. Human Polyclonal DNASE2 Primary Antibody for IHC (p), WB - ABIN318974 : Krieser, Eastman: The cloning and expression of human deoxyribonuclease II. A possible role in apoptosis. in The Journal of biological chemistry 1998 (PubMed)
    Show all 3 references for 318974

更多抗Deoxyribonuclease II, Lysosomal的相互作用对抗体

Fruit Fly (Drosophila melanogaster) Deoxyribonuclease II, Lysosomal (DNASE2) interaction partners

  1. These results confirm that DNase II and the ability to clear macromolecular DNA is essential for maintaining proper immune function in Drosophila.

  2. findings indicate that DNaseII can act cell autonomously to degrade DNA during nonapoptotic cell death.

Mouse (Murine) Deoxyribonuclease II, Lysosomal (DNASE2) interaction partners

  1. holocrine secretion is a DNase2-mediated form of programmed cell death and suggest that autophagy-dependent metabolism, DNA degradation

  2. Data show that Klf1 (显示 KLF1 抗体) is expressed in central macrophagse of erythroblastic islands and that it binds and activates the promoter of Dnase2a.

Human Deoxyribonuclease II, Lysosomal (DNASE2) interaction partners

  1. Single nucleotide polymorphisms producing a loss-of-function variant of the enzymes in DNASE1 (显示 DNASE1 抗体), DNASE1L3 (显示 DNASE1L3 抗体), and DNASE2, possibly serving as a genetic risk factor for autoimmune diseases, were confirmed.

  2. 15 nonsynonymous human DNase II SNPs were genotyped in three ethnic groups including 16 different populations using the PCR-restriction fragment length polymorphism technique.

  3. study demonstrated the relationship of genotypes/haplotypes with the in vivo DNase II and promoter activities; significant correlations between genotype in each rheumatoid arthritis (RA)-related SNP and enzymatic activity levels were found; alleles associated with RA exhibited a reduction in serum DNase II activity.

  4. upregulation of expression during myelomonocytic differentiation of HL-60 and THP-1 (显示 GLI2 抗体) cells

  5. Sp1 (显示 PSG1 抗体) and Sp3 (显示 SP3 抗体) are involved in up-regulation of this enzyme's transcriptoin during cell differentiation of hl-60 cells.

  6. the enzyme is a monomeric phospholipase D (显示 PLD 抗体)-family member with a pseudodimeric protein fold

  7. The association of SNPs in the 5'-regulatory region of the DNA degrading enzyme DNASE2 with Rheumatoid Arthritis implies a role for this enzyme in the pathogenesis of this autoimmune disease.

Pig (Porcine) Deoxyribonuclease II, Lysosomal (DNASE2) interaction partners

  1. Proteolytic processing of porcine deoxyribonuclease II occurs in lysosomes but is not required for enzyme activation

  2. Data showed an association between PARP-1 and LEI/L-DNase II.

Deoxyribonuclease II, Lysosomal (DNASE2) 抗原简介

蛋白简介

This gene encodes a member of the DNase family. The protein, located in the lysosome, hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized, DNASE2*L (low activity) and DNASE2*H (high activity), that differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record.

Gene names and symbols associated with DNASE2

  • Deoxyribonuclease II (DNaseII) 抗体
  • deoxyribonuclease II, lysosomal (dnase2) 抗体
  • deoxyribonuclease II, lysosomal (DNASE2) 抗体
  • deoxyribonuclease II, lysosomal (LOC733868) 抗体
  • deoxyribonuclease II (dnase2) 抗体
  • deoxyribonuclease II alpha (Dnase2a) 抗体
  • deoxyribonuclease II, lysosomal (Dnase2) 抗体
  • CG7780 抗体
  • DDBDRAFT_0188966 抗体
  • DDBDRAFT_0252883 抗体
  • DDB_0188966 抗体
  • DDB_0252883 抗体
  • dDNase II 抗体
  • Dmel\\CG7780 抗体
  • DNase 抗体
  • DNase-1 抗体
  • DNase1 抗体
  • DNase 1 抗体
  • Dnase2 抗体
  • Dnase2a 抗体
  • DNL 抗体
  • DNL2 抗体
  • fa92d01 抗体
  • LOC733868 抗体
  • MGC80103 抗体
  • wu:fa56d08 抗体
  • wu:fa92d01 抗体

Protein level used designations for DNASE2

deoxyribonuclease II , CG7780-PA , DNaseII-PA , acid DNase , deoxyribonuclease 1 , deoxyribonuclease II, lysosomal , deoxyribonuclease-2-alpha , fa56d08 , DNase II alpha , lysosomal DNase II , DNase II, lysosomal , R31240_2 , deoxyribonuclease II alpha

GENE ID SPECIES
48228 Drosophila melanogaster
446506 Xenopus laevis
476697 Canis lupus familiaris
733868 Xenopus (Silurana) tropicalis
747576 Pan troglodytes
100000399 Danio rerio
100171654 Pongo abelii
100599185 Nomascus leucogenys
8627734 Dictyostelium discoideum AX4
13423 Mus musculus
1777 Homo sapiens
171575 Rattus norvegicus
282218 Bos taurus
397398 Sus scrofa
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