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DRAP1 蛋白

(DR1-Associated Protein 1 (Negative Cofactor 2 Alpha) (DRAP1))

Transcriptional repression is a general mechanism for regulating transcriptional initiation in organisms ranging from yeast to humans. Accurate initiation of transcription from eukaryotic protein-encoding genes requires the assembly of a large multiprotein complex consisting of RNA polymerase II and general transcription factors such as TFIIA, TFIIB, and TFIID. DR1 is a repressor that interacts with the TATA-binding protein (TBP) of TFIID and prevents the formation of an active transcription complex by precluding the entry of TFIIA and/or TFIIB into the preinitiation complex. The protein encoded by this gene is a corepressor of transcription that interacts with DR1 to enhance DR1-mediated repression. The interaction between this corepressor and DR1 is required for corepressor function and appears to stabilize the TBP-DR1-DNA complex. [provided by RefSeq, Jul 2008].

recommended

DRAP1 Protein (AA 1-205) (GST tag) (ABIN1352006)

DRAP1 宿主: 人宿主: 小麦胚 Recombinant ELISA, WB, AA, AP

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recommended

DRAP1 Protein (AA 2-105) (GST tag) (ABIN1352008)

DRAP1 宿主: 人宿主: 小麦胚 Recombinant ELISA, WB, AA, AP

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recommended

DRAP1 Protein (AA 2-205) (His tag) (ABIN3084282)

Crystallography grade DRAP1 宿主: 人宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys

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DRAP1 蛋白 by Grade

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DRAP1 蛋白 by Origin

Find DRAP1 蛋白 for a variety of species such as anti-Human DRAP1, anti-Cow DRAP1, anti-Mouse DRAP1. The species listed below are among those available. Click on a link to go to the corresponding products.

DRAP1 蛋白 by Source

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DRAP1 蛋白 by 蛋白类型

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DRAP1 蛋白 by 应用范围

Find DRAP1 蛋白 validated for a specific application such as ELISA, WB, AP, AA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular DRAP1 蛋白

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

DRAP1 Protein (AA 1-205) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1352006

Quantity 10 μg

Datasheet Datasheet

DRAP1 Protein (AA 2-105) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1352008

Quantity 10 μg

Datasheet Datasheet

DRAP1 Protein (AA 2-205) (His tag)

Reactivity Human

Source Insect Cells

Validations

Cat. No. ABIN3084282

Quantity 1 mg

Datasheet Datasheet

DRAP1 Protein (AA 2-205) (His tag)

Reactivity Mouse

Source Insect Cells

Validations

Cat. No. ABIN3129167

Quantity 1 mg

Datasheet Datasheet

DRAP1 Protein (AA 4-198, partial) (GST tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN1046948

Quantity 100 μg

Datasheet Datasheet

DRAP1 Protein (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2719758

Quantity 20 μg

Datasheet Datasheet

DRAP1 Protein (AA 2-205) (His tag)

Reactivity Rat

Source Yeast

Validations

Cat. No. ABIN1475249

Quantity 1 mg

Datasheet Datasheet

DRAP1 Protein (AA 2-205) (His tag)

Reactivity Cow

Source Yeast

Validations

Cat. No. ABIN1625796

Quantity 1 mg

Datasheet Datasheet

Latest Publications for our DRAP1 蛋白

Burkard, Planyavsky, Kaupe, Breitwieser, Bürckstümmer, Bennett, Superti-Furga, Colinge: "Initial characterization of the human central proteome." in: BMC systems biology, Vol. 5, pp. 17, (2011) (PubMed).

Klejman, Pereira, van Zeeburg, Gilfillan, Meisterernst, Timmers: "NC2alpha interacts with BTAF1 and stimulates its ATP-dependent association with TATA-binding protein." in: Molecular and cellular biology, Vol. 24, Issue 22, pp. 10072-82, (2004) (PubMed).

Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).

Goppelt, Stelzer, Lottspeich, Meisterernst: "A mechanism for repression of class II gene transcription through specific binding of NC2 to TBP-promoter complexes via heterodimeric histone fold domains." in: The EMBO journal, Vol. 15, Issue 12, pp. 3105-16, (1996) (PubMed).

Mermelstein, Yeung, Cao, Inostroza, Erdjument-Bromage, Eagelson, Landsman, Levitt, Tempst, Reinberg: "Requirement of a corepressor for Dr1-mediated repression of transcription." in: Genes & development, Vol. 10, Issue 8, pp. 1033-48, (1996) (PubMed).

Aliases for DRAP1 蛋白

DR1-associated protein 1 (negative cofactor 2 alpha) (drap1) 蛋白
DR1 associated protein 1 (DRAP1) 蛋白
Dr1 associated protein 1 (negative cofactor 2 alpha) (Drap1) 蛋白
Dr1 associated protein 1 (Drap1) 蛋白
2310074H19Rik 蛋白
DRAP1 蛋白
fb26e10 蛋白
NC2-alpha 蛋白
wu:fb26e10 蛋白
zgc:56003 蛋白
zgc:77337 蛋白

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Popular DRAP1 蛋白

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Aliases for DRAP1 蛋白

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