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DPH5 encodes a component of the diphthamide synthesis pathway. 再加上，我们可以发DPH5 蛋白 (9) 和 DPH5 抗体 (5)和数多这个蛋白质的别的产品。
The yeast and Chinese hamster homologs of human DPH5 catalyze the trimethylation step in the biosynthesis of diphthamide
Misfolded AR protein in the cytosol thus initiates a cascade of events beginning with JNK (显示 MAPK8 ELISA试剂盒) and culminating in Bax (显示 BAX ELISA试剂盒)-dependent, intrinsic pathway activation, mediated in part by DP5/Hrk (显示 HRK ELISA试剂盒).
This gene encodes a component of the diphthamide synthesis pathway. Diphthamide is a post-translationally modified histidine residue found only on translation elongation factor 2. It is conserved from archaebacteria to humans, and is targeted by diphtheria toxin and Pseudomonas exotoxin A to halt cellular protein synthesis. The yeast and Chinese hamster homologs of this protein catalyze the trimethylation of the histidine residue on elongation factor 2, resulting in a diphthine moiety that is subsequently amidated to yield diphthamide. Multiple transcript variants encoding different isoforms have been found for this gene.
, diphthamide biosynthesis methyltransferase
, diphthine synthase
, protein x 0011