anti-Cytoskeleton Associated Protein 2 (CKAP2) 抗体

CKAP2 is a cytoskeleton-associated protein involved in mitotic progression (Seki and Fang, 2007. 再加上,我们可以发Cytoskeleton Associated Protein 2 蛋白 (5)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
CKAP2 26586 Q8WWK9
CKAP2 80986 Q3V1H1
CKAP2 306575  

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通过反应活性、应用领域、克隆类型和共轭标记 CKAP2 抗体

特性 应用范围 宿主 克隆类型 标记
Human , , , ,
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Mouse (Murine) , ,


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Rat (Rattus) , ,


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更多抗Cytoskeleton Associated Protein 2的相互作用对抗体

Human Cytoskeleton Associated Protein 2 (CKAP2) interaction partners

  1. Chromatin CKAP2 is an independent prognostic marker for relapse-free survival in early-stage breast cancer, and could potentially replace the mitotic activity index in clinical evaluation of proliferation activity.

  2. The transcriptional activity of RHOA (显示 RHOA 抗体), SEMA3B (显示 SEMA3B 抗体), and CKAP2 genes was assessed in blood samples of leukaemia patients and healthy donors.

  3. CKAP2 is involved in the maintenance of microtubule nucleation sites

  4. GC box was responsible for the cyclic activity of human CKAP2 promoter through the phosphorylation of Sp1 (显示 PSG1 抗体), possibly by Cyclin A (显示 CCNA2 抗体)/Cdk (显示 CDK4 抗体) complex.

  5. Findings suggest that the motif surrounding Ser627 ((625) RRSRRL (630)) is a critical for kinase-substrate recognition and for regulation of the subcellular localization of TMAP during mitosis.

  6. TMAP is limited to pre-anaphase stages and suggest that the multiple phosphorylation may not act in concert but serve diverse functions.

  7. CKAP2 comprises nine exons ranging 70-1442 bp and is about 22 kb in size (regulatory regions included). The CKAP2 promoter contains CCAAT (-39...-33) rather than the canonical TATA box, and harbors nine binding sites for six transcription factors

  8. Data show that degradation of TMAP/CKAP2 during mitotic exit is mediated by the anaphase-promoting complex bound to Cdh1 (显示 CDH1 抗体) and that the KEN (显示 PCNT 抗体) box motif near the N terminus is necessary for its destruction.

  9. CKAP2 is a physiological substrate of anaphase-promoting complex (显示 CDC26 抗体)/cyclosome during mitotic exit and that a tight regulation of the CKAP2 protein level is critical for the normal mitotic progression.

  10. Cdk1 (显示 CDK1 抗体)-cyclin B1 (显示 CCNB1 抗体)-mediated phosphorylation of TMAP is important for and contributes to proper regulation of microtubule dynamics and establishment of functional bipolar spindles during mitosis

Mouse (Murine) Cytoskeleton Associated Protein 2 (CKAP2) interaction partners

  1. we found that Lb1-null epicardial cells have a delayed nuclear morphology change in vivo, suggesting that Lb1 facilitates morphological changes associated with migration. These findings suggest that Lb1 contributes to nuclear shape maintenance and migration of epicardial cells

  2. These data suggest a physiological role of CKAP2 in the formation of spindle bipolarity, which is necessary for maintaining chromosomal stability.

  3. These findings suggest that CKAP2 is a new MAP with microtubule-stabilizing properties

  4. Data suggest the existence of a functional positive feedback loop in which Ckap2 activates the G1 tetraploidy checkpoint and prevents aneuploidy.

  5. The cellular functions of TMAP/CKAP2 might be regulated by timely phosphorylation and dephosphorylation during the course of mitosis.

  6. Our present findings demonstrate that TMAP/CKAP2 is essential for proper chromosome segregation and for maintaining genomic stability.

Cytoskeleton Associated Protein 2 (CKAP2) 抗原简介

蛋白简介

CKAP2 is a cytoskeleton-associated protein involved in mitotic progression (Seki and Fang, 2007

Gene names and symbols associated with CKAP2

  • cytoskeleton associated protein 2 (CKAP2) 抗体
  • cytoskeleton associated protein 2 (Ckap2) 抗体
  • AI461656 抗体
  • AW228814 抗体
  • LB1 抗体
  • se20-10 抗体
  • TMAP 抗体

Protein level used designations for CKAP2

cytoskeleton-associated protein 2 , intracellular protein , cytoskeleton associated protein 2 , cytoskeleton-associated protein 2-like , CTCL tumor antigen se20-10 , tumor- and microtubule-associated protein , tumor-associated microtubule-associated protein

GENE ID SPECIES
100052303 Equus caballus
418882 Gallus gallus
100515274 Sus scrofa
26586 Homo sapiens
80986 Mus musculus
306575 Rattus norvegicus
515249 Bos taurus
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