COX10 蛋白
(Cytochrome C Oxidase Assembly Homolog 10 (COX10))
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes heme A:farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. This protein is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation, which results in the substitution of a lysine for an asparagine (N204K), is identified to be responsible for cytochrome c oxidase deficiency. In addition, this gene is disrupted in patients with CMT1A (Charcot-Marie-Tooth type 1A) duplication and with HNPP (hereditary neuropathy with liability to pressure palsies) deletion. [provided by RefSeq, Jul 2008].
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COX10 蛋白 by Origin
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Popular COX10 蛋白
Aliases for COX10 蛋白
cytochrome c oxidase assembly protein 10 (Cox10) 蛋白COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor (cox10) 蛋白
COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor L homeolog (cox10.L) 蛋白
COX10, heme A:farnesyltransferase cytochrome c oxidase assembly factor (COX10) 蛋白
cytochrome c oxidase 10 (COX10) 蛋白
protoheme IX farnesyltransferase, mitochondrial (LOC100732273) 蛋白
COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor (Cox10) 蛋白
2410004F01Rik 蛋白
AU042636 蛋白
Cox10 蛋白
cytochrome c oxidase 10 蛋白
F4I1.50 蛋白
F4I1_50 蛋白
im:7145568 蛋白
im:7157205 蛋白
wu:fb18a03 蛋白
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